Leptomeningeal Cancer in the Pediatric Patient

  • Kathleen A. Neville
  • Susan M. Blaney
Part of the Cancer Treatment and Research book series (CTAR, volume 125)


The treatment and prophylaxis of leptomeningeal leukemia and lymphoma in children has dramatically improved disease control and long-term survival. However, the treatment of other leptomeningeal cancers has been less successful and the neurologic morbidity associated with central nervous system-directed therapy has a significant long-term impact on quality of life. Further research is critical to identify new therapeutic strategies for children with or at high risk for leptomeningeal cancer.

Key words

Acute lymphoblastic leukemia neuroblastoma craniospinal irradiation prophylactic intrathecal therapy medulloblastoma 


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Copyright information

© Springer Science+Business Media, Inc. 2005

Authors and Affiliations

  • Kathleen A. Neville
    • 1
  • Susan M. Blaney
    • 1
  1. 1.Texas Children's Cancer CenterBaylor College of MedicineHouston

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