1. Abstract
Many important physiological processes involve changes in cell volume, e.g., the transport of salt and water in epithelial cells and the contraction of muscle cells. These cells respond to swelling with a so-called regulatory volume decrease which involves the activation of K+ channels. However, the molecular identity of the involved K+ channels has not been clear, and in particular, the mechanism for activation has been obscure.
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2. References
M. Grunnet, T. Jespersen, N. MacAulay, N.K. Jorgensen, N. Schmitt, O. Pongs, S.P. Olesen and D.A. Klaerke, KCNQ1 channels sense small changes in cell volume, J. Physiol., 2003, published online.
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© 2004 Springer Science+Business Media, Inc.
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Grunnet, M. et al. (2004). KCNQ Channels are Sensors of Cell Volume. In: Lauf, P.K., Adragna, N.C. (eds) Cell Volume and Signaling. Advances in Experimental Medicine and Biology, vol 559. Springer, Boston, MA. https://doi.org/10.1007/0-387-23752-6_38
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DOI: https://doi.org/10.1007/0-387-23752-6_38
Publisher Name: Springer, Boston, MA
Print ISBN: 978-0-387-23299-7
Online ISBN: 978-0-387-23752-7
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