Skip to main content
  • 512 Accesses

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 159.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

Adenocarcinoma General

  • Hammar S, Bockus D, Remington F: Metastatic tumors of unknown origin: An ultrastructural analysis of 265 cases. Ultrastruct Pathol 11:209–250, 1987.

    CAS  PubMed  Google Scholar 

  • McDowell EM, Hess FG Jr, Trump BF: Epidermoid metaplasia, carcinoma in situ and carcinomas of the lung. In Trump BF, Jones RT, eds: Diagnostic Electron Microscopy, Vol 3. John Wiley and Sons, New York, 1980, 37–96.

    Google Scholar 

Thyroid

  • Dickersin GR, Vickery AL, Smith SB: Papillary carcinoma of the thyroid, oxyphil cell type, “cell type” variant: A light-and electron-microscopic study. Am J Surg Pathol 4:501–509, 1980.

    CAS  PubMed  Google Scholar 

  • Johannessen JV, Sobrinho-Simoes M: The fine structure of follicular thyroid adenomas. Am J Clin Pathol 78:299–310, 1982.

    CAS  PubMed  Google Scholar 

  • Klinck GH, Oertel JE, Winship T: Ultrastructure of normal human thyroid. Lab Invest 22:2–22, 1970.

    CAS  PubMed  Google Scholar 

  • Olson JL, Penney DP, Averill KA: Fine structural studies of a human thyroid adenoma, with special reference to psammoma bodies. Hum Pathol 8:103–111, 1977.

    CAS  PubMed  Google Scholar 

  • Sobrinho-Simoes MA, Nesland JM, Holm R, et al: Transmission electron microscopy and immunocytochemistry in the diagnosis of thyroid tumors. Ultrastruct Pathol 9:255–275, 1985.

    CAS  PubMed  Google Scholar 

Breast

  • Ahmed A: Atlas of the Ultrastructure of Human Breast Disease. Churchill Livingstone, Edinburgh, 1978.

    Google Scholar 

  • Battifora H: Intracytoplasmic lumina in breast carcinoma. Arch Pathol Lab Med 99:614–617, 1975.

    CAS  Google Scholar 

  • Fisher ER: Ultrastructure of the human breast and its disorders. Am J Clin Pathol 66:291–375, 1976.

    CAS  PubMed  Google Scholar 

  • Gould VE, Jao W, Battifora H: Ultrastructural analysis in the differential diagnosis of breast tumors. Pathol Res Pract 167:45–70, 1980.

    CAS  PubMed  Google Scholar 

  • Nesland JM, Holm R: Diagnostic problems in breast pathology: The benefit of ultrastructural and immunocytochemical analysis. Ultrastruct Pathol 11:293–311, 1987.

    CAS  PubMed  Google Scholar 

  • Ozzello L: Breast. In Johannessen JV, ed: Electron Microscopy in Human Medicine, Urogenital System and Breast, vol 9. McGraw-Hill, London, 1979, 409–456.

    Google Scholar 

  • Ozello L: Ultrastructure of the human mammary gland. In Sommers SC, ed: Pathology Annual 1971. Appleton-Century-Crofts, New York, 1971, pp 1–59.

    Google Scholar 

  • Sobrinho-Simoes M, Johannessen JV, Gould VE: The diagnostic significance of intracytoplasmic lumina in metastatic neoplasms. Ultrastruct Pathol 2:327–335, 1981.

    CAS  PubMed  Google Scholar 

Lung

  • Bedrossian CWM, Weilbaecher DG, Bentinck DC, et al: Ultrastructure of human bronchioloalveolar cell carcinoma. Cancer 36:1399–1413, 1975.

    CAS  PubMed  Google Scholar 

  • Bolen JW, Thorning D: Histogenetic classification of pulmonary carcinomas. Peripheral adenocarcinomas studied by light microscopy, histochemistry and electron microscopy. Pathol Annu 17:77–100, 1982.

    PubMed  Google Scholar 

  • Coalson JJ, Mohr JA, Pirtle JK, et al: Electron microscopy of neoplasms of the lung with special emphasis on the alveolar cell carcinoma. Am Rev Respir Dis 101:181–197, 1970.

    CAS  PubMed  Google Scholar 

  • Eimoto T, Teshima K, Shirakusa T, et al: Ultrastructure of well-differentiated adenocarcinomas of the lung with special reference to bronchioloalveolar carcinoma. Ultrastruct Pathol 8:177–190, 1985.

    CAS  PubMed  Google Scholar 

  • Greenberg SD, Smith MN, Spjut HJ: Bronchiolo-alveolar carcinoma—cell of origin. Am J Clin Pathol 63:153–167, 1975.

    CAS  PubMed  Google Scholar 

  • Hammar SP: Adenocarcinoma and large cell carcinoma of the lung. Ultrastruct Pathol 11:263–291, 1987.

    CAS  PubMed  Google Scholar 

  • Hammar SP, Bolen JW, Bockus D, et al: Ultrastructural and immunohistochemical features of common lung tumors: An overview. Ultrastruct Pathol 9:283–318, 1985.

    CAS  PubMed  Google Scholar 

  • Kuhn C: Fine ultrastructure of bronchiolo-alveolar cell carcinoma. Cancer 30:1107–1118, 1972.

    CAS  PubMed  Google Scholar 

  • McDowell EM, Barrett LA, Glavin F, et al: The respiratory epithelium. 1. Human bronchus. J Natl Cancer Inst 61:539–549, 1978.

    CAS  PubMed  Google Scholar 

  • McDowell EM, Hess FG Jr, Trump BF: Epidermoid metaplasia, carcinoma in situ and carcinomas of the lung. In Trump BF, Jones RT, eds: Diagnostic Electron Microscopy, vol 3. John Wiley and Sons, New York, 1980, 37–96.

    Google Scholar 

  • Sidhu GS: The ultrastructure of malignant epithelial neoplasms of the lung. Pathol Annu 17:235–266, 1982.

    PubMed  Google Scholar 

Gastrointestinal and Sinonasal Region

  • Barnes L: Intestinal-type adenocarcinoma of the nasal cavity and paranasal sinuses. Am J Surg Pathol 10:192–202, 1986.

    CAS  PubMed  Google Scholar 

  • Batsakis JG, Mackay B, Ordonez NG: Enteric-type adenocarcinoma of the nasal cavity. An electron microscopic and immunocytochemical study. Cancer 54:855–860, 1984.

    CAS  PubMed  Google Scholar 

  • Cooper PH, Warkel RL: Ultrastructure of the goblet cell type of adenocarcinoid of the appendix. Cancer 42:2687–2695, 1978.

    CAS  PubMed  Google Scholar 

  • Hickey WF, Seiler MW: Ultrastructural markers of colonic adenocarcinoma. Cancer 47:140–145, 1981.

    CAS  PubMed  Google Scholar 

  • Kaye GI, Fenoglio CM, Pascal RR, et al: Comparative electron microscopic features of normal, hyperplastic and adenomatous human colonic epithelium. Variations in cellular structure relative to the process of epithelial differentiation. Gastroenterology 64:926–945, 1973.

    CAS  PubMed  Google Scholar 

  • Mills SE, Fechner RE, Cantrell RW: Aggressive sinonasal lesion resembling normal intestinal mucosa. Am J Surg Pathol 6:803–809, 1982.

    CAS  PubMed  Google Scholar 

  • Nevalainen TV, Jarvi OH: Ultrastructure of intestinal and diffuse type gastric carcinoma. J Pathol 122:129–136, 1977.

    Article  CAS  PubMed  Google Scholar 

  • Schmid KO, Aubock L, Albegger K: Endocrine amphicrine enteric carcinoma of the nasal mucosa. Virchows Arch [A] 383:329–343, 1979.

    Article  CAS  Google Scholar 

  • Yamashiro K, Suzuki H, Nagayo T: Electron microscopic study of signet-ring cells in diffuse carcinoma of the stomach. Virchows Arch [A] 374:275–284, 1977.

    Article  CAS  Google Scholar 

Liver

  • Alpert LI, Zak FG, Werthamer S, et al: Cholangiocarcinoma: A clinicopathologic study of five cases with ultrastructural observations. Hum Pathol 5:709–728, 1974.

    CAS  PubMed  Google Scholar 

  • Becker FF: Hepatoma—Nature’s model tumor. Am J Pathol 74:179–210, 1974.

    CAS  PubMed  Google Scholar 

  • Denk H, Franke WW, Dragosics B, et al: Pathology of cytoskeleton of liver cells: Demonstration of Mallory bodies (alcoholic hyalin) in murine and human hepatocytes by immunofluorescence microscopy using antibodies to cytokeratin polypeptides from hepatocytes. Hepatology 1:9–20, 1981.

    CAS  PubMed  Google Scholar 

  • Franke WW, Denk H, Schmid E, et al: Ultrastructural, biochemical, and immunologic characterization of Mallory bodies in livers of griseofulvin-treated mice. Fimbriated rods of filaments containing prekeratin-like polypeptides. Lab Invest 40:207–220, 1979.

    CAS  PubMed  Google Scholar 

  • French SW: The Mallory body: Structure, composition and pathogenesis. Hepatology 1:76–83, 1981.

    CAS  PubMed  Google Scholar 

  • Ghadially FN, Parry EW: Ultrastructure of a human hepatocellular carcinoma and surrounding non-neoplastic liver. Cancer 19:1989–2004, 1966.

    CAS  PubMed  Google Scholar 

  • Ghadially FN: Mallory’s bodies. In Ultrastructural Pathology of the Cell and Matrix. A Text and Atlas of Physiological and Pathological Alterations in the Fine Structure of Cellular and Extracellular Components, 3rd ed, vol 2. Butterworths, London, 1988, 902–905.

    Google Scholar 

  • Horie A, Kotoo Y, Hayashi I: Ultrastructural comparison of hepatoblastoma and hepatocellular carcinoma. Cancer 44:2184–2193.

    Google Scholar 

  • Keeley AF, Iseri OA, Gottlieb LS: Ultrastructure of hyaline cytoplasmic inclusions in a human hepatoma: Relationship to Mallory’s alcoholic hyalin. Gastroenterology 62:280–293, 1972.

    CAS  PubMed  Google Scholar 

  • Lapis K, Johannesson JV: Pathology of primary liver cancer. J Toxicol Environ Health 5:315–355, 1979.

    CAS  PubMed  Google Scholar 

  • Ordonez NG, Mackay B: Ultrastructure of liver cell and bile duct carcinomas. Ultrastruct Pathol 5:201–241, 1983.

    CAS  PubMed  Google Scholar 

  • Phillips MJ: Mallory bodies and the liver [editorial]. Lab Invest 47:311–313, 1982.

    CAS  PubMed  Google Scholar 

  • Phillips MJ, Poucell S, Patterson J, et al: Liver tumors and tumor-like conditions. In The Liver. An Atlas and Text of Ultrastructural Pathology. Raven Press, New York, 1987, 447–517.

    Google Scholar 

  • Schaff Z, Lapis K, Safrany L: The ultrastructure of primary hepatocellular cancer in man. Virchows Arch [A] 352:340–358, 1971.

    CAS  Google Scholar 

  • Smuckler EA: The ultrastructure of human alcoholic hyalin. Am J Clin Pathol 49:790–797, 1968.

    CAS  PubMed  Google Scholar 

  • Tanikawa K: Ultrastructural Aspects of the Liver and Its Disorders, 2nd ed. Igaku-Shoin, Tokyo, 1979, 338–348.

    Google Scholar 

  • Toker C, Trevino N: Ultrastructure of human primary hepatic carcinoma. Cancer 19:1594–1606, 1966.

    CAS  PubMed  Google Scholar 

Pancreas

  • Albores-Saavedra J, Angeles-Angeles A, Nadji M, et al: Mucinous cystadenocarcinoma of the pancreas. Morphologic and immunocytochemical observations. Am J Surg Pathol 11:11–20, 1987.

    CAS  PubMed  Google Scholar 

  • Albores-Saavedra J, Gould EW, Angeles-Angeles A, et al: Cystic tumors of the pancreas. Pathol Annu 25:19–50, 1990.

    PubMed  Google Scholar 

  • Alpert LC, Truong LD, Bossart MI, et al: Microcystic adenoma (serous cystadenoma) of the pancreas. Am J Surg Pathol 12:251–263, 1988.

    CAS  PubMed  Google Scholar 

  • Bombi JA, Milla A, Badal JM, et al: Papillary-cystic neoplasms of the pancreas. Report of two cases and review of the literature. Cancer 54:780–784, 1984.

    CAS  PubMed  Google Scholar 

  • Boor PJ, Swanson MR: Papillary-cystic neoplasm of the pancreas. Am J Surg Pathol 3:69–75, 1979.

    CAS  PubMed  Google Scholar 

  • Chaudhry AP, Cutler LS, Leifer C, et al: Histogenesis of acinic cell carcinoma of the major and minor salivary glands. An ultrastructural study. J Pathol 148:307–320, 1986.

    CAS  PubMed  Google Scholar 

  • Compagno J, Oertel JE: Microcystic adenomas of the pancreas (glycogen-rich cystadenomas). A clinicopathologic study of 34 cases. Am J Clin Pathol 69:289–298, 1978.

    CAS  PubMed  Google Scholar 

  • Echevarria RA: Ultrastructure of the acinic cell carcinoma and clear cell carcinoma of the parotid gland. Cancer 20:563–571, 1967.

    CAS  PubMed  Google Scholar 

  • Erlandson RA, Tandler B: Ultrastructure of acinic cell carcinoma of the parotid gland. Arch Pathol 93:130–140, 1972.

    CAS  PubMed  Google Scholar 

  • Gustafsson H, Carlsoo B, Henriksson R: Ultrastructural morphology and secretory behavior of acinic cell carcinoma. Cancer 55:1706–1710, 1985.

    CAS  PubMed  Google Scholar 

  • Jorgensen LJ, Hansen AB, Burcharth F, et al: Solid and papillary neoplasm of the pancreas. Ultrastruct Pathol 16:659–666, 1992.

    CAS  PubMed  Google Scholar 

  • Kay S, Schatzki PF: Ultrastructure of acinic cell carcinoma of the parotid salivary gland. Cancer 29:235–244, 1972.

    CAS  PubMed  Google Scholar 

  • Kim YI, Seo JW, Suh JS, et al: Microcystic adenomas of the pancreas. Am J Clin Pathol 94:150–156, 1990.

    CAS  PubMed  Google Scholar 

  • Klimstra DS, Heffess CS, Oertel JE, et al: Acinar cell carcinoma of the pancreas. A clinicopathologic study of 28 cases. Am J Surg Pathol 16:815–837, 1992.

    CAS  PubMed  Google Scholar 

  • Lack EE: Primary tumors of the exocrine pancreas. Classification, overview, and recent contributions by immunohistochemistry and electron microscopy [review]. Am J Surg Pathol 13:66–88, 1989.

    PubMed  Google Scholar 

  • Laitio M, Lev R, Orlic D: The developing human fetal pancreas: An ultrastructural and histochemical study with special reference to exocrine cells. J Anat 117:619–634, 1974.

    CAS  PubMed  Google Scholar 

  • Lewandrowski K, Warshaw K, Compton C: Macrocystic serous cystadenoma of the pancreas: A morphologic variant differing from microcystic adenoma. Hum Pathol 23:871–875, 1992.

    Article  CAS  PubMed  Google Scholar 

  • Lieber MR, Lack EE, Roberts JR, et al: Solid and papillary epithelial neoplasm of the pancreas. An ultrastructural and immunocytochemical study of six cases. Am J Surg Pathol 11:85–93, 1987.

    CAS  PubMed  Google Scholar 

  • Lo JW, Fung CHK, Yonan TN, et al: Cystadenoma of the pancreas. An ultrastructural study. Cancer 39:2470–2474, 1977.

    CAS  PubMed  Google Scholar 

  • Miettinen M, Partanen S, Fraki O, et al: Papillary cystic tumor of the pancreas. An analysis of cellular differentiation by electron microscopy and immunohistochemistry Am J Surg Pathol 11:855–865, 1987.

    CAS  PubMed  Google Scholar 

  • Morrison DM, Jewell LD, McCaughey WTE, et al: Papillary cystic tumor of the pancreas. Arch Pathol Lab Med 108:723–727, 1984.

    CAS  PubMed  Google Scholar 

  • Munger BL: The ultrastructure of the exocrine pancreas. In Carey LC, ed: The Pancreas. C.V. Mosby, St Louis, 1973, 17–31.

    Google Scholar 

  • Nyongo A, Huntrakoon M: Microcystic adenoma of the pancreas with myoepithelial cells. A hitherto undescribed morphologic feature. Am J Clin Pathol 84:114–120, 1985.

    CAS  PubMed  Google Scholar 

  • Osborne BM, Culbert SJ, Cangir A, et al: Acinar cell carcinoma of the pancreas in a 9-year-old child: Case report with electron microscopic observations. South Med J 70:370–372, 1977.

    CAS  PubMed  Google Scholar 

  • Pettinato G, Manivel JC, Ravetto C, et al: Papillary cystic tumor of the pancreas. A clinicopathologic study of 20 cases with cytologic, immunohistochemical, ultrastructural, and flow cytometric observations, and a review of the literature. Am J Clin Pathol 98:478–488, 1992.

    CAS  PubMed  Google Scholar 

  • Schlosnagle DC, Campbell WG Jr: The papillary and solid neoplasm of the pancreas. A report of two cases with electron microscopy, one containing neurosecretory granules. Cancer 47:2603–2610, 1981.

    CAS  PubMed  Google Scholar 

  • Shorten SD, Hart WR, Petras RE: Microcystic adenomas (serous cystadenomas) of pancreas. A clinicopathologic investigation of eight cases with immunohistochemical and ultrastructural studies. Am J Surg Pathol 10:365–372, 1986.

    CAS  PubMed  Google Scholar 

  • Toner PG, Carr KE, McLay ALC: The exocrine pancreas. In Johannessen JV, ed. Electron Microscopy in Human Medicine, Digestive System, vol 7. McGraw-Hill, London, 1980, 211–245.

    Google Scholar 

  • Webb JN: Acinar cell neoplasms of the exocrine pancreas. J Clin Pathol 30:103–112, 1977.

    CAS  PubMed  Google Scholar 

Kidney

  • Akhtar M, Kardar H, Linjawi T, et al: Chromophobe cell carcinoma of the kidney. A clinocopathologic study of 21 cases. Am J Surg Pathol 19:1245–1256, 1995.

    CAS  PubMed  Google Scholar 

  • Beckwith JB, Palmer NF: Histopathology and prognosis of Wilm’s tumor: Results from the First National Wilm’s Tumor Study. Cancer 41:1937–1948, 1978.

    CAS  PubMed  Google Scholar 

  • Bennington JL, Beckwith JB: Tumors of the kidney, renal pelvis, and ureter. In Firminger HI, ed: Atlas of Tumor Pathology, fasc 12. Armed Forces Institute of Pathology, Washington, DC, 1975, 156–159.

    Google Scholar 

  • Delong WH, Sakr W, Grignon DJ: Chromophobe renal cell carcinoma. A comparative histochemical and immunohistochemical study. J Urol Pathol 4:1–8, 1996.

    Google Scholar 

  • Dicker sin GR, Colvin RB: Pathology of renal tumors. In Skinner DG, Lieskovsky eds: Diagnosis and Management of Genitourinary Cancer, 2nd ed. WB Saunders, Philadelphia, 1988, 122–123.

    Google Scholar 

  • Fisher ER, Horvart B: Comparative ultrastructural study of so-called renal adenoma and carcinoma. J Urol 108:382–386, 1972.

    CAS  PubMed  Google Scholar 

  • Gerharz CD, Moll R, Storkel S, et al: Establishment and characterization of two divergent cell lines derived from a human chromophobe renal cell carcinoma. Am J Pathol 146:953–962, 1995.

    CAS  PubMed  Google Scholar 

  • Hirano A, Zimmerman HM: Fenestrated blood vessels in metastatic renal carcinoma in the brain. Lab Invest 26:465–468, 1972.

    CAS  PubMed  Google Scholar 

  • Oberling C, Riviere M, Haguenau F: Ultrastructure of the clear cells in renal carcinomas and its importance for the demonstration of their origin. Nature 186:402, 1960.

    CAS  PubMed  Google Scholar 

  • Sarjanen K, Hjelt L: Ultrastructural characteristics of human renal cell carcinoma in relation to the light microscopic grading. Scand J Urol Nephrol 12:57–65, 1978.

    Google Scholar 

  • Seljelid R, Ericsson JL: Electron microscopic observations on specialization of the cell surface in renal clear cell carcinoma. Lab Invest 14:435–447, 1965.

    CAS  PubMed  Google Scholar 

  • Storkel S, Steart PV, Drenckhahn D, et al: The human chromophobe cell renal carcinoma: Its probable relation to intercalated cells of the collecting duct. Virchows Arch [B] 56:237–245, 1989.

    CAS  Google Scholar 

  • Sun CN, Bissada NK, White HJ, et al: Spectrum of ultrastructural patterns of renal cell adenocarcinoma. Urology 9:159–200, 1977.

    Article  Google Scholar 

  • Tannenbaum M: Ultrastructural pathology of human renal cell tumors. Pathol Annu 6:249–277, 1971.

    CAS  PubMed  Google Scholar 

  • Thoenes W, Storkel S, Rumpelt H-J: Human chromophobe cell renal carcinoma. Virchows Arch [Cell Pathol] 48:207–217, 1985.

    CAS  Google Scholar 

Prostate

  • Brennick JB, O’Connell JX, Dickersin GR, et al: Lipofuscin pigmentation (so called “melanosis”) of the prostate. Am J Surg Pathol 18:446–454, 1994.

    CAS  PubMed  Google Scholar 

  • Fisher ER, Jeffrey W: Ultrastructure of human normal and neoplastic prostate. Am J Clin Pathol 44:119–134, 1965.

    CAS  PubMed  Google Scholar 

  • Mao P, Nakao K, Angrist A: Human prostatic carcinoma: An electron microscopic study. Cancer Res 26:955–973, 1966.

    CAS  PubMed  Google Scholar 

  • Mau P, Angrist A: The fine structure of the basal cell of human prostate. Lab Invest 15:1768–1782, 1966.

    Google Scholar 

  • Sinha AA, Blackard CE: Ultrastructure of prostatic benign hyperplasia and carcinoma. Urology 2:114–120, 1973.

    Article  CAS  PubMed  Google Scholar 

  • Srigley JR, Hartwick WJ, Edwards V, et al: Selected ultrastructural aspects of urothelial and prostatic tumors [review]. Ultrastruct Pathol 12:49–65, 1988.

    CAS  PubMed  Google Scholar 

  • Takayasu H, Yamaguchi Y: An electron microscopic study of the prostatic cancer cell. J Urol 87:935–940, 1962.

    CAS  PubMed  Google Scholar 

  • Tannenbaum M, Tannenbaum S: Ultrastructural pathology of human prostatic carcinoma. In Trump BF, Jones RT, eds: Diagnostic Electron Microscopy, vol 3. John Wiley and Sons, New York, 1980, 175–201.

    Google Scholar 

Adrenal Cortex

  • Case Records of the Massachusetts General Hospital (Case 17-1977). N Engl J Med 296:988–994, 1977.

    Google Scholar 

  • Case Records of the Massachusetts General Hospital (Case 23-1979). N Engl J Med 300:1322–1328, 1979.

    Google Scholar 

  • Drachenberg CB, Lee HK, Gann DS, et al: Adrenal cortical carcinoma with adenosquamous differentiation. Report of a case with immunohistochemical and ultrastructural studies. Arch Pathol Lab Med 119:260–265, 1995.

    CAS  PubMed  Google Scholar 

  • El-Naggar AK, Evans DB, Mackay B: Oncocytic adrenal cortical carcinoma. Ultrastruct Pathol 15:549–556, 1991.

    CAS  PubMed  Google Scholar 

  • Erlandson RA, Reuter VE: Oncocytic adrenal cortical adenoma. Ultrastruct Pathol 15:539–547, 1991.

    CAS  PubMed  Google Scholar 

  • Erlandson RA, Nesland JM: Tumors of the endocrine/neuroendocrine system: An overview [review]. Ultrastruct Pathol 18:149–170, 1994.

    CAS  PubMed  Google Scholar 

  • Fawcett DW: Adrenal glands. In Bloom and Fawcett: A Textbook of Histology, 12th ed. Chapman and Hall, New York, 1994, 503–515.

    Google Scholar 

  • Garret R, Ames RP: Black-pigmented adenoma of the adrenal gland. Report of three cases including electron microscopic study. Arch Pathol 95:349–353, 1973.

    CAS  PubMed  Google Scholar 

  • Jones EC, Pins M, Dickersin GR, et al: Metanephric adenoma of the kidney. A clinicopathological, immunohistochemical, flow cytometric, cytogenetic, and electron microscopic study of seven cases. Am J Surg Pathol 19:615–626, 1995.

    CAS  PubMed  Google Scholar 

  • Hogan TF, Gilchrist KW, Westring DW, et al: A clinical and pathological study of adrenocortical carcinoma. Therapeutic implications. Cancer 45:2880–2883, 1980.

    CAS  PubMed  Google Scholar 

  • King DR, Lack EE: Adrenal cortical carcinoma. A clinical and pathologic study of 49 cases. Cancer 44:239–244, 1979.

    CAS  PubMed  Google Scholar 

  • Long JA, Jones AL: Observations on the fine structure of the adrenal cortex of man. Lab Invest 17:355–369, 1967.

    CAS  PubMed  Google Scholar 

  • Mackay B, El-Naggar A, Ordonez NG: Ultrastructure of adrenal cortical carcinoma. Ultrastruct Pathol 18:181–190, 1994.

    CAS  PubMed  Google Scholar 

  • Molberg K, Vuitch F, Stewart D, et al: Adrenocortical blastoma. Hum Pathol 23:1187–1190, 1992.

    Article  CAS  PubMed  Google Scholar 

  • Nader S, Hickey RC, Sellin RV, et al: Adrenal cortical carcinoma. A study of 77 cases. Cancer 52:707–711, 1983.

    CAS  PubMed  Google Scholar 

  • Osanai T, Konta A, Chui D, et al: Electron microscopic findings in benign deoxycorticosterone and 11-deoxycortisol-producing adrenal tumor. Arch Pathol Lab Med 114:829–831, 1990.

    CAS  PubMed  Google Scholar 

  • Page DL, Hough AJ, Gray GF: Diagnosis and prognosis of adrenocortical neoplasms. Arch Pathol Lab Med 110:993–994, 1986.

    CAS  PubMed  Google Scholar 

  • Perez-Ordonez B, Hamed G, Campbell S, et al: Renal oncocytoma: A clinicopathologic study of 70 cases. Am J Surg Pathol 21:871–883, 1997.

    Article  CAS  PubMed  Google Scholar 

  • Rhodin JAG: Adrenal cortex. In An Atlas of Ultrastructure. WB Saunders, Philadelphia, 1963, 140–141.

    Google Scholar 

  • Sasano H, Suzuki T, Sano T, et al: Adrenocortical oncocytoma. A true nonfunctioning adrenocortical tumor. Am J Surg Pathol 15:949–956, 1991.

    CAS  PubMed  Google Scholar 

  • Silva EG, Mackay B, Samaan NA, et al: Adrenocortical carcinomas: An ultrastructural study of 22 cases. Ultrastruct Pathol 3:1–7, 1982.

    CAS  PubMed  Google Scholar 

  • Spark RF: Low renin hypertension and the adrenal cortex. Semin Med Beth Israel Hosp 287:343–350, 1972.

    CAS  Google Scholar 

  • Symington T: Summary of the ultrastructural features of cells found in the pathological human adrenal. In Functioning Pathology of the Human Adrenal Gland. E&S Livingstone Ltd, Edinburgh, 1969, pp 476–484.

    Google Scholar 

  • Weiss LM: Comparative histologic study of 43 metastasizing and nonmetastasizing adrenocortical tumors. Am J Surg Pathol 8:163–169, 1984.

    CAS  PubMed  Google Scholar 

  • Young RH, Dunn J, Dickersin GR: An unusual oncocytic renal tumor with sarcomatoid foci and osteogenic differentiation. Arch Pathol Lab Med 112:937–940, 1988.

    CAS  PubMed  Google Scholar 

Squamous Cell Carcinoma General

  • Chen SY, Harwick RD: Ultrastructure of oral squamous cell carcinoma. Oral Surg 44:744–753, 1977.

    CAS  PubMed  Google Scholar 

  • Inoue S, Dionne GP: Tonofilaments in normal human bronchial epithelium and in squamous cell carcinoma. Am J Pathol 88:345–354, 1977.

    CAS  PubMed  Google Scholar 

  • McDowell EM, Hess FG Jr, Trump BF: Epidermoid metaplasia, carcinoma in situ and carcinoma of the lung. In Trump BF, Jones RT, eds: Diagnostic Electron Microscopy, vol 3. John Wiley and Sons, New York, 1980, 37–96.

    Google Scholar 

Thymoma

  • Bearman RM, Levine GD, Bensch KG: The ultrastructure of the normal human thymus: A study of 36 cases. Anat Rec 190:755–782, 1978.

    Article  CAS  PubMed  Google Scholar 

  • Bloodworth JMB, Hiratsuka H, Hickey RC, et al: Ultrastructure of the human thymus, thymic tumors, and myasthenia gravis. Pathol Annu 10:329–391, 1975.

    PubMed  Google Scholar 

  • Eimoto T, Teshima K, Shirakusa T, et al: Heterogeneity of epithelial cells and reactive components in thymomas: An ultrastructural and immunohistochemical study. Ultrastruct Pathol 10:157–173, 1986.

    CAS  PubMed  Google Scholar 

  • Hammond EH, Flinner RL: The diagnosis of thymoma: A review. Ultrastruct Pathol 15:419–438, 1991.

    CAS  PubMed  Google Scholar 

  • Levine GD, Bensch KG: Epithelial nature of spindle-cell thymoma. An ultrastructural study. Cancer 30:500–511, 1972.

    CAS  PubMed  Google Scholar 

  • Levine GD, Med M, Rosai J, et al: The fine structure of thymoma, with emphasis on its differential diagnosis. Am J Pathol 81:49–86, 1975.

    CAS  PubMed  Google Scholar 

  • Levine GD, Rosai J: Thymic hyperplasia and neoplasia: A review of current concepts. Hum Pathol 9:495–515, 1978.

    CAS  PubMed  Google Scholar 

  • Lewis JE, Wick MR, Scheithauer BW, et al: Thymoma: A clinicopathologic review. Cancer 60:2727–2743, 1987.

    CAS  PubMed  Google Scholar 

  • Marino M, Muller-Hermelink HK: Thymoma and thymic carcinoma: Relation of thymoma epithelial cells to the cortical and medullary differentiation of the thymus. Virchows Arch [A] 407:119–149, 1985.

    CAS  Google Scholar 

  • Moran CA, Suster S: Current status of the histologic classification of thymoma. Int J Surg Pathol 3:67–72, 1995.

    Google Scholar 

  • Pascoe HR, Miner MS: An ultrastructural study of nine thymomas. Cancer 37:317–326, 1976.

    CAS  PubMed  Google Scholar 

  • Rosai J, Levine GD: Tumors of the thymus. In Firminger HI, ed: Atlas of Tumor Pathology, 2nd series, Fasc 13. Armed Forces Institute of Pathology, Washington, DC, 1976.

    Google Scholar 

  • Snover DC, Levine GD, Rosai J: Thymic carcinoma. Five distinctive histological variants. Am J Surg Pathol 6: 451–470, 1982.

    CAS  PubMed  Google Scholar 

  • Suster S, Rosai J: Histology of the normal thymus. Am J Surg Pathol 14:284–303, 1990.

    CAS  PubMed  Google Scholar 

  • Suster S, Rosai J: Thymic carcinoma: A clinicopathologic study of 60 cases. Cancer 67:1025–1032, 1991.

    CAS  PubMed  Google Scholar 

  • Truong LD, Mody DR, Cagle PT, et al: Thymic carcinoma: A clinicopathologic study of 13 cases. Am J Surg Pathol 14:151–166, 1990.

    CAS  PubMed  Google Scholar 

  • van de Wijngaert FP, Kendall MD, Schuurman H-J, et al: Heterogeneity of epithelial cells in the human thymus. An ultrastructural study. Cell Tissue Res 237:227–237, 1984.

    Article  PubMed  Google Scholar 

  • Walker AN, Mills SE, Fechner RE: Thymomas and thymic carcinomas. Semin Diagn Pathol 7:250–265, 1990.

    CAS  PubMed  Google Scholar 

  • Wick MR, Weiland LH, Scheithauer B, et al: Primary thymic carcinomas. Am J Surg Pathol 6:613–630, 1982.

    CAS  PubMed  Google Scholar 

Adamantinoma

  • Knapp RH, Wick MR, Scheithauer BW, et al: Adamantinoma of bone. An electron microscopic and immunohistochemical study. Virchows Arch [A] 398:75–86, 1982.

    CAS  Google Scholar 

  • Morai H, Yamamoto S, Hiramatsu K, et al: Adamantinoma of the tibia. Ultrastructural and immunohistochemic study with reference to histogenesis. Clin Orthop Rel Res 190:299–310, 1984.

    Google Scholar 

  • Pieterse AS, Smith PS, McClure J: Adamantinoma of long bones: Clinical, pathological and ultrastructural features. J Clin Pathol 35:780–786, 1982.

    CAS  PubMed  Google Scholar 

  • Perez-Atayde AR, Kozakewich HPW, Vawter GF: Adamantinoma of the tibia. An ultrastructural and immunohistochemical study. Cancer 55:1015–1023, 1985.

    CAS  PubMed  Google Scholar 

  • Povysil C, Matejovsky Z: Ultrastructure of adamantinoma of long bone. Virchows Arch [A] 393:233–244, 1981.

    CAS  Google Scholar 

  • Rosai J: Adamantinoma of the tibia. Electron microscopic evidence of its epithelial origin. Am J Clin Pathol 51:786–792, 1969.

    CAS  PubMed  Google Scholar 

  • Yoneyama T, Winter WG, Milsow L: Tibial adamantinoma: Its histogenesis from ultrastructural studies. Cancer 40:1138–1142, 1977.

    CAS  PubMed  Google Scholar 

Transitional Cell (Urothelial) Carcinoma

  • Battifore H, Eisenstein R, McDonald JH: The human urinary bladder mucosa. An electron microscopic study. Invest Urol 1:354–361, 1974.

    Google Scholar 

  • Fulker MJ, Cooper EH, Tanaka T: Proliferation and ultrastructure of papillary transitional cell carcinoma of the human bladder. Cancer 27:71–82, 1971.

    CAS  PubMed  Google Scholar 

  • Koss LG: Some ultrastructural aspects of experimental and human carcinoma of the bladder. Cancer Res 37:20–24, 1977.

    Google Scholar 

  • Tannenbaum M: Light and electron microscopy of urothelial cancer. Carcinoma in situ. Urology 8:498–501, 1976.

    CAS  PubMed  Google Scholar 

Undifferentiated Carcinoma

  • de-Thé G, Vuillaume M, Giovanella BC, et al:: Epithelial characteristics of tumor cells in nasopharyngeal carcinoma passaged in nude mice: Ultrastructure. J Natl Cancer Inst 57:1101–1105, 1976.

    PubMed  Google Scholar 

  • Gazzolo L, de-Thé G, Vuillaume M, et al: Nasopharyngeal carcinoma. II. Ultrastructure of normal mucosa, tumor biopsies, and subsequent epithelial growth in vitro. JNCI 48:73–86, 1972.

    CAS  PubMed  Google Scholar 

  • Hammar S: Adenocarcinoma and large cell undifferentiated carcinoma of the lung. Ultrastruct Pathol 11:263–291, 1987.

    CAS  PubMed  Google Scholar 

  • Prasad U: Cells of origin of nasopharyngeal carcinoma: An electron microscopic study. J Laryngol Otol 88:1087–1094, 1974.

    CAS  PubMed  Google Scholar 

  • Svoboda DJ, Kirchner FR, Shanmugaratnam K: The fine structure of nasopharyngeal carcinomas. In Muir CS, Shanmugaratnam K, eds: UICC Monograph Series, vol 1. Munksgaard, Copenhagen, 1967, 163–171.

    Google Scholar 

  • Svoboda DJ, Kirchner FR, Shanmugaratnam K: Ultrastructure of nasopharyngeal carcinomas in American and Chinese patients: An application of electron microscopy to geographic pathology. Exp Mol Pathol 4:189–204, 1965.

    Article  Google Scholar 

Melanoma General

  • Carlson JA, Dickersin GR, Sober AJ, et al. Desmoplastic neurotropic melanoma. A clinicopathologic analysis of 28 cases. Cancer 75:478–494, 1995.

    CAS  PubMed  Google Scholar 

  • Clark WH, Bretton R: A comparative fine structural study of melanogenesis in normal human epidermal melanocytes and in certain human malignant melanoma cells. In Helwig E, Mostofi FK, eds: The Skin, International Academy of Pathology, monograph 10. Williams and Wilkins, Baltimore, 1971, 192–214.

    Google Scholar 

  • Curran RC, McCann BG: The ultrastructure of benign pigmented nevi and melanocarcinomas in man. J Pathol 119:135–146, 1976.

    Article  CAS  PubMed  Google Scholar 

  • Erlandson RA: Ultrastructural diagnosis of amelanotic malignant melanoma: Aberrant melanosomes, myelin figures or lysosomes? Ultrastruct Pathol 11:191–208, 1987

    CAS  PubMed  Google Scholar 

  • Hernandez FJ: Malignant blue nevus. A light and electron microscopic study. Arch Dermatol 107:741–744, 1973.

    Article  CAS  PubMed  Google Scholar 

  • Jimbow K, Miura S, Ito Y, et al: Characterization of melanogenesis and morphogenesis of melanosomes by physio-chemical properties of melanin and melanosomes in malignant melanoma. Cancer Res 44:1128–1134, 1984.

    CAS  PubMed  Google Scholar 

  • Klug H, Gunther JW: Ultrastructural differences in human malignant melanomata. An electron microscopical study. Br J Dermatol 86:395–407, 1972.

    CAS  PubMed  Google Scholar 

  • Mackay B, Ayala AG: Intracisternal tubules in human melanoma cells. Ultrastruct Pathol 1:1–6, 1980.

    CAS  PubMed  Google Scholar 

  • Mazur MT, Katzenstein A-LA: Metastatic melanoma: The spectrum of ultrastructural morphology. Ultrastruct Pathol 1:337–356, 1980.

    CAS  PubMed  Google Scholar 

Clear Cell Sarcoma

  • Argenyi ZB, Cain C, Bromley C, et al: S-100 protein-negative malignant melanoma: Fact or fiction? A light-microscopic and immunohistochemical study. Am J Dermatopathol 16:233–240, 1994.

    CAS  PubMed  Google Scholar 

  • Azumi N, Turner RR: Clear cell sarcoma of tendons and aponeuroses: Electron microscopic findings suggesting Schwann cell differentiation. Hum Pathol 14:1084–1089, 1983.

    CAS  PubMed  Google Scholar 

  • Benson JD, Kraemer BB, Mackay B: Malignant melanoma of soft parts: An ultrastructural study of four cases. Ultrastruct Pathol 8:57–70, 1985.

    CAS  PubMed  Google Scholar 

  • Boudreaux D, Waisman J: Clear cell sarcoma with melanogenesis. Cancer 41:1387–1394, 1978.

    CAS  PubMed  Google Scholar 

  • Chung EB, Enzinger FM: Malignant melanoma of soft parts. A reassessment of clear cell sarcoma. Am J Surg Pathol 7:405–413, 1983.

    CAS  PubMed  Google Scholar 

  • Hoffman GJ, Carter D: Clear cell sarcoma of tendons and aponeuroses with melanin. Arch Pathol 95:22–25, 1973.

    CAS  PubMed  Google Scholar 

  • Kindblom L-G, Lodding P, Angervall L: Clear-cell sarcoma of tendons and aponeuroses. An immunohistochemical and electron microscopic analysis indicating neural crest origin. Virchows Arch [A] 401:109–128, 1983.

    CAS  Google Scholar 

  • Kubo T: Clear cell sarcoma of patellar tendon studied by electron microscopy. Cancer 24:948–953, 1969.

    CAS  PubMed  Google Scholar 

  • Mukai M, Torikata C, Iri H, et al: Histogenesis of clear cell sarcoma of tendons and aponeuroses. An electronmicroscopic, biochemical, enzyme histochemical, and immunohistochemical study. Am J Pathol 114:264–272, 1984.

    CAS  PubMed  Google Scholar 

  • Ohno T, Park P, Utsunomiya Y, et al: Ultrastructural study of a clear cell sarcoma suggesting Schwannian differentiation. Ultrastruct Pathol 10:39–48, 1986.

    CAS  PubMed  Google Scholar 

  • Parker JB, Marcus PB, Martin JH: Spinal melanotic clear-cell sarcoma: A light and electron microscopic study. Cancer 46:718–724, 1980.

    CAS  PubMed  Google Scholar 

Ballon Cell Melanoma

  • Hashimoto K, Bale GF: An electron microscopic study of balloon cell nevus. Cancer 30:530–540, 1972.

    CAS  PubMed  Google Scholar 

  • Kao GF, Helwig EB, Graham JH: Balloon cell malignant melanoma of the skin. A clinicopathologic study of 34 cases with histochemical, immunohistochemical, and ultrastructural observations. Cancer 69:2942–2952, 1992.

    CAS  PubMed  Google Scholar 

  • Khalil MK: Balloon cell malignant melanoma of the choroid: Ultrastructural studies. Br J Ophthalmol 67:579–584, 1983.

    CAS  PubMed  Google Scholar 

  • Ranchod M: Metastatic melanoma with balloon cell changes. Cancer 30:1006–1013, 1972.

    CAS  PubMed  Google Scholar 

  • Sondergaard K, Henschel A, Hou-Jensen K: Metastatic melanoma with balloon cell changes: An electron microscopic study. Ultrastruct Pathol 1:357–360, 1980.

    CAS  PubMed  Google Scholar 

Mesothelioma (Epithelial Type)

  • Bedrosian CW, Bonsib S, Moran C: Differential diagnosis between mesothelioma and adenocarcinoma: A multimodal approach based on ultrastructure and immunocytochemistry. Semin Diagn Pathol 9:124–140, 1992.

    Google Scholar 

  • Bolen JW, Hammar SP, McNutt MA: Serosal tissue: Reactive tissue as a model for understanding mesotheliomas. Ultrastruct Pathol 11:251–262, 1987.

    CAS  PubMed  Google Scholar 

  • Burns TR, Greenberg SD; Mace ML, et al: Ultrastructural diagnosis of epithelial malignant mesothelioma. Cancer 56:2036–2040, 1985.

    CAS  PubMed  Google Scholar 

  • Burns TR, Johnson EH, Cartwright J, et al: Desmosomes of epithelial malignant mesothelioma. Ultrastruct Pathol 12:385–388, 1988.

    CAS  PubMed  Google Scholar 

  • Carstens PH: Contact between abluminal microvilli and collagen fibrils in metastatic adenocarcinoma and mesothelioma. J Pathol 166:179–182, 1992.

    Article  CAS  PubMed  Google Scholar 

  • Coleman M, Henderson DW, Mukherjee TM: The ultrastructural pathology of malignant pleural mesothelioma. Pathol Annu 24:303–353, 1989.

    PubMed  Google Scholar 

  • Dardick I, Al-Jabi M, McCaughey WTE, et al: Ultrastructure of poorly differentiated diffuse epithelial mesotheliomas. Ultrastruct Pathol 7:151–160, 1984.

    CAS  PubMed  Google Scholar 

  • Dardick I, Al-Jabi M, McCaughey WTE, et al: Diffuse epithelial mesothelioma: A review of the ultrastructural spectrum. Ultrastruct Pathol 11:503–533, 1987.

    CAS  PubMed  Google Scholar 

  • Davis JMG: Ultrastructure of human mesotheliomas. J Natl Cancer Inst 52:1715–1725, 1974.

    CAS  PubMed  Google Scholar 

  • Hammar SP: The pathology of benign and malignant pleural disease [review]. Chest Surg Clin North Am 4: 405–430, 1994.

    CAS  Google Scholar 

  • Katsube Y, Mukai K, Silverberg SG: Cystic mesothelioma of the peritoneum. A report of five cases and review of the literature. Cancer 50:1615–1622, 1982.

    CAS  PubMed  Google Scholar 

  • Legrand M, Pariente R: Ultrastructural study of pleural fluid in mesothelioma. Thorax 29:164–171, 1974.

    CAS  PubMed  Google Scholar 

  • Leong AS, Stevens MW, Mukherjee TM: Malignant mesothelioma: Cytologic diagnosis with histologic, immunohistochemical, and ultrastructural correlation. Semin Diagn Pathol 9:141–150, 1992.

    CAS  PubMed  Google Scholar 

  • Luse SA, Spjut HJ: An electron microscopic study of a solitary pleural mesothelioma. Cancer 17:1546–1554, 1964.

    CAS  PubMed  Google Scholar 

  • McCaughey WTE, Colby TV, Battifora H, et al: Diagnosis of diffuse malignant mesothelioma: Experience of a US/Canadian mesothelioma panel. Mod Pathol 4:342–353, 1991.

    CAS  PubMed  Google Scholar 

  • Mennemeyer R, Smith M: Multicystic, peritoneal mesothelioma. A report with electron microscopy of a case mimicking intra-abdominal cystic hygroma (lymphangioma). Cancer 44:692–698, 1979.

    CAS  PubMed  Google Scholar 

  • Suzuki Y, Chung J, Kannerstein M: Ultrastructure of human malignant diffuse mesothelioma. Am J Pathol 85:241–262, 1976.

    CAS  PubMed  Google Scholar 

  • Suzuki Y, Kannerstein M, Chung J: Ultrastructure of human mesothelioma [abstract]. Am J Pathol 70:7, 1973.

    Google Scholar 

  • Torikata C, Kawai T, Nakayama M: Confronting cisternae and ciliated cells in malignant pleural mesothelioma: An ultrastructural study. Ultrastruct Pathol 15:249–256, 1991.

    CAS  PubMed  Google Scholar 

  • Warhol MJ, Corson JM: An ultrastructural comparison of mesotheliomas with adenocarcinomas of the lung and breast. Hum Pathol 16:50–55, 1985.

    CAS  PubMed  Google Scholar 

  • Weidner N: Malignant mesothelioma of peritoneum. Ultrastruct Pathol 15:515–520, 1991.

    CAS  PubMed  Google Scholar 

  • Wick MR, Loy T, Mills SE, et al: Malignant epitheliod pleural mesothelioma versus peripheral pulmonary adeno-carcinoma: A histochemical, ultrastructural, and immunohistologic study of 103 cases. Hum Pathol 21: 759–766, 1990.

    Article  CAS  PubMed  Google Scholar 

Mesothelioma (Spindle Cell Type)

  • Benisch B, Peison B, Sobel HJ, et al: Fibrous mesotheliomas (pseudofibroma) of the scrotal sac: A light and ultrastructural study. Cancer 47:731–735, 1981.

    CAS  PubMed  Google Scholar 

  • Bolen JW, Hammar SP, McNutt MA: Reactive and neoplastic serosal tissue. A light-microscopic, ultrastructural, and immunocytochemical study. Am J Surg Pathol 10:34–47, 1986.

    CAS  PubMed  Google Scholar 

  • Briselli M, Mark EJ, Dickersin GR: Solitary fibrous tumors of the pleura: Eight new cases and review of 360 cases in the literature. Cancer 47:2678–2689, 1981.

    CAS  PubMed  Google Scholar 

  • Burrig KF, Kastendieck H: Ultrastructural observations on the histogenesis of localized fibrous tumors of the pleura (benign mesothelioma). Virchows Arch [A] 403:413–424, 1984.

    CAS  Google Scholar 

  • El-Naggar A, Ro JY, Ayala AG, et al: Localized fibrous tumor of the serosal cavities. Immunohistochemical, electron-microscopic, and flow-cytometric DNA study. Am J Clin Pathol 92:561–565, 1989.

    CAS  PubMed  Google Scholar 

  • Hammar SP, Bolen JW: Sarcomatoid pleural mesothelioma. Ultrastruct Pathol 9:337–343, 1985.

    CAS  PubMed  Google Scholar 

  • Kawai T, Mikata A, Torikata C, et al: Solitary (localized) pleural mesothelioma. A light and electron microscopic study. Am J Surg Pathol 2:365–375, 1978.

    CAS  PubMed  Google Scholar 

  • Kay S, Silverberg SG: Ultrastructural studies of a malignant fibrous mesothelioma of the pleura. Arch Pathol Lab Med 92:449–455, 1971.

    CAS  Google Scholar 

  • Osamura RY: Ultrastructure of localized fibrous mesothelioma of the pleura. Report of a case with histogenetic considerations. Cancer 39:139–142, 1977.

    CAS  PubMed  Google Scholar 

  • Said JW, Nash G, Banks-Shlegal S, et al: Localized fibrous mesothelioma: An immunohistochemical and electron microscopic study. Hum Pathol 15:440–443, 1984.

    CAS  PubMed  Google Scholar 

  • Steinetz C, Clarke R, Jacobs GH, et al: Localized fibrous tumors of the pleura: Correlation of histopathological, immunohistochemical and ultrastructural features. Pathol Res Pract 186:344–357, 1990.

    CAS  PubMed  Google Scholar 

  • Witkin GB, Rosai J: Solitary fibrous tumor of the mediastinum. A report of 14 cases. Am J Surg Pathol 13:547–557, 1989.

    CAS  PubMed  Google Scholar 

  • Yousem SA, Flynn SD: Intrapulmonary localized fibrous tumor. Intraparenchymal so-called localized fibrous mesothelioma. Am J Clin Pathol 89:365–369, 1988.

    CAS  PubMed  Google Scholar 

Large Cell Lymphoma

  • Azar HA, Jaffe ES, Berard CW, et al: Diffuse large cell lymphomas (reticulum cell sarcomas, histiocytic lymphomas). Correlation of morphologic features with functional markers. Cancer 46:1428–1441, 1980.

    CAS  PubMed  Google Scholar 

  • Azar HA, Espinoza CG, Richman AV, et al: “Undifferentiated” large cell malignancies: An ultrastructural and immunocytochemical study. Hum Pathol 13:323–333, 1982.

    CAS  PubMed  Google Scholar 

  • Bacchi MM, Bacchi CE, Gown AM, et al: Diversity of morphologic, immunocytochemical, and molecular biological findings in Ki-1 (CD30-positive) large cell lymphomas. IAP Abstract #393, 1991.

    Google Scholar 

  • Banks PM, Metter J, Allred DC: Anaplastic large cell (Ki-1) lymphoma with histiocytic phenotype simulating carcinoma. Am J Clin Pathol 94:445–452, 1990.

    CAS  PubMed  Google Scholar 

  • Bernier V, Azar HA: Filiform large-cell lymphomas: An ultrastructural and immunohistochemical study. Am J Surg Pathol 11:387–396, 1987.

    CAS  PubMed  Google Scholar 

  • Bitter MA, Franklin WA, Larson RA, et al: Morphology in Ki-(CD30)-positive non-Hodgkin’s lymphoma is correlated with clinical features and the presence of a unique chromosomal abnormality, t(2;5)(p23;q35). Am J Surg Pathol 14:305–316, 1990.

    CAS  PubMed  Google Scholar 

  • Burns BF, Cripps C, Dardick I: A case of Ki-1 large cell anaplastic lymphoma with ultrastructural features. Hum Pathol 20:393–396, 1989.

    Article  CAS  PubMed  Google Scholar 

  • Carstens HB: Anemone cell tumor revisited [editorial]. Ultrastruct Pathol 16:iii–v, 1992.

    CAS  PubMed  Google Scholar 

  • Chan JKC, Banks PM, Cleary ML, et al: A revised European-American classification of lymphoid neoplasms proposed by the International Lymphoma Study Group. A summary version. Am J Clin Pathol 103: 543–560, 1995.

    CAS  PubMed  Google Scholar 

  • Dardick I, Srinivasan R, Al-Jabi M: Signet-ring cell variant of large cell lymphoma. Ultrastruct Pathol 5:195–200, 1983.

    CAS  PubMed  Google Scholar 

  • Dardick I, Cavell S, Moher D, et al: Ultrastructural morphometric study of follicular center lymphocytes: I. Nuclear characteristics and the Lukes-Collins’ concept. Ultrastruct Pathol 13:373–391, 1989.

    CAS  PubMed  Google Scholar 

  • Dehner LP: Here we go again: A new classification of malignant lymphomas. A viewpoint from the trenches [editorial]. Am J Clin Pathol 103:539–540, 1995.

    CAS  PubMed  Google Scholar 

  • Dickersin GR: Electron microscopy of leukemias and lymphomas. Clin Lab Med 7(1):199–247, 1987.

    CAS  PubMed  Google Scholar 

  • Erlandson RA, Filippa DA: Unusual non-Hodgkin’s lymphomas and true histiocytic lymphomas. Ultrastruct Pathol 13:258–260, 1989.

    Google Scholar 

  • Gillespie JJ: The ultrastructural diagnosis of diffuse large cell (“histiocytic”) lymphoma: Fine structural study of 30 cases. Am J Surg Pathol 2:9–20, 1978.

    CAS  PubMed  Google Scholar 

  • Henry K: Electron microscopy in the non-Hodgkin’s lymphomata. Br J Cancer 31:73–93, 1975.

    PubMed  Google Scholar 

  • Glick AD, Leech JH, Waldron JA, et al: Malignant lymphomas of follicular center cell origin in man. II. Ultrastructure and cytochemical studies. J Natl Cancer Inst 54:23–36, 1975.

    CAS  PubMed  Google Scholar 

  • Iossifides I, Mackay B, Butler JJ: Signet-ring cell lymphoma. Ultrastruct Pathol 1:511–517, 1980.

    CAS  PubMed  Google Scholar 

  • Kinney MC, Glick AD, Stein H, et al: Comparison of anaplastic large cell Ki-1 lymphomas and microvillous lymphomas in their immunologic and ultrastructural features. Am J Surg Pathol 14:1047–1060, 1990.

    CAS  PubMed  Google Scholar 

  • Kinney MC, Collins RD, Greer JP, et al: A small-cell-predominant variant of primary Ki-1 (CD30)+ T-cell lymphoma. Am J Surg Pathol 17:859–868, 1993.

    CAS  PubMed  Google Scholar 

  • Levine GD, Dorfman RF: Nodular lymphoma: An ultrastructural of its relationship to germinal centers on a correlation of light and electron microscopic findings. Cancer 35:148–164, 1975.

    CAS  PubMed  Google Scholar 

  • Michel RP, Case BW, Moinuddin M: Immunoblastic lymphosarcoma: A light immunofluorescence, and electron microscopic study. Cancer 43:224–236, 1979.

    CAS  PubMed  Google Scholar 

  • Osborne BM, Mackay B, Butler JJ, et al. Large cell lymphoma with microvillus-like projections: An ultrastructural study. Am J Clin Pathol 79:443–450, 1983.

    CAS  PubMed  Google Scholar 

  • Rivas C, Piris MA, Gamallo C, et al: Ultrastructure of 26 cases of Ki-1 lymphomas: Morphoimmunologic correlation. Ultrastruct Pathol 14:381–397, 1990.

    CAS  PubMed  Google Scholar 

  • Said JW, Hargreaves HK, Pinkus GS: Non-Hodgkin’s lymphomas: An ultrastructural study correlating morphology with immunologic cell type. Cancer 44:504–528, 1979.

    CAS  PubMed  Google Scholar 

  • Sibley R, Rosai J, Froelich W, Battifora H: Comments by the panel. Ultrastruct Pathol 8:369–373, 1985.

    Google Scholar 

  • Stein H, Mason DY, Gerdes J, et al: The expression of the Hodgkin’s disease associated antigen Ki-1 in reactive and neoplastic lymphoid tissue: Evidence that Reed-Sternberg cells and histiocytic malignancies are derived from activated lymphoid cells. Blood 66:848–858, 1985.

    CAS  PubMed  Google Scholar 

  • Taccagani GL, Terreni MR, Rovere E, Villa E, Cantaboni A: Anaplastic large cell Ki-1 lymphoma of the stomach with villopodial projections: An immunocytochemical and ultrastructural study and review of the literature. Ultrastruct Pathol 16:291–302, 1992.

    Google Scholar 

  • Yowell R, Hammond E: Ki-1 lymphoma: A case report. Ultrastruct Pathol 16:11–16, 1992.

    CAS  PubMed  Google Scholar 

Hemophagocytic Syndrome and Histiocytic Sarcoma

  • Chen R-L, Su I-J, Lin K-H, et al: Fulminant childhood hemophagocytic syndrome mimicking histiocytic medullary reticulosis. An atypical form of Epstein-Barr virus infection. Am J Clin Pathol 96:171–176, 1991.

    CAS  PubMed  Google Scholar 

  • Chin NW, Gangi M, Fani K, et al: Colonic histiocytic neoplasm mimicking malignant histiocytosis and presenting as intussusception. Hum Pathol 26:682–687, 1995.

    Article  CAS  PubMed  Google Scholar 

  • Dickersin GR: Electron microscopy of leukemias and lymphomas. Clin Lab Med 7(1):199–247, 1987.

    CAS  PubMed  Google Scholar 

  • DiSant’Agnese P, Ettinger LJ, Ryan CK, et al: Histiomonocytic malignancy. A spectrum of disease in an 11-month-old infant. Cancer 52:1417–1422, 1983.

    CAS  Google Scholar 

  • Favara BE, Feller AC, Paulli M, et al: Contemporary classification of histiocytic disorders. The WHO Committee on Histiocytic/Reticulum Cell Proliferations. Reclassification Working Group of the Histiocytic Society. Med Pediatr Oncol 29(3):157–166, 1997.

    Article  CAS  PubMed  Google Scholar 

  • Ferster A, Corazza F, Heimann P, et al: Anaplastic large cell lymphoma of true histiocytic origin in an infant: Unusual clinical, hematological, and cytogenetic features. Med Pediatr Oncol 22:147–152, 1994.

    CAS  PubMed  Google Scholar 

  • Heustis DG, Bull BS, Hadley GG: Ultrastructure of the spleen in malignant histiocytosis. Arch Pathol Lab Med 101:239–242, 1977.

    CAS  PubMed  Google Scholar 

  • Huhn D, Meister P: Malignant histiocytosis. Morphologic and cytochemical findings. Cancer 42:1341–1349, 1978.

    CAS  PubMed  Google Scholar 

  • Isaacson P, Wright DH, Jones DB: Malignant lymphoma of true histiocytic (monocyte/macrophage) origin. Cancer 51:80–91, 1983.

    CAS  PubMed  Google Scholar 

  • Jaffe ES: Malignant histiocytosis and true histiocytic lymphoma. In Surgical Pathology of the Lymph Nodes and Related Organs, 2nd ed. Major Problems in Pathology, vol 16. WB Saunders, Philadelphia, 1995, 560–593.

    Google Scholar 

  • Koo CH, Reifel J, Kogut N, et al: True histiocytic malignancy associated with a malignant teratoma in a patient with 46XY gonadal dysgenesis. Am J Surg Pathol 16:175–183, 1992.

    CAS  PubMed  Google Scholar 

  • Lampert IA, Catovsky D, Bergier N: Malignant histiocytosis: A clinicopathologic study of 12 cases. Br J Haematol 40:65–77, 1978.

    CAS  PubMed  Google Scholar 

  • Lombardi L, Carbone A, Pilotti S, et al: Malignant histiocytosis: A histological and ultrastructural study of lymph nodes in six cases. Histopathology 2:315–328, 1978.

    CAS  PubMed  Google Scholar 

  • Salisbury JR, Hall PA, Williams HC, et al: Multicentric reticulohistiocytosis. Detailed immunophenotyping confirms macrophage origin. Am J Surg Pathol 14:687–693, 1990.

    CAS  PubMed  Google Scholar 

  • Salyer J, Craven CM: Malignant histiocytosis in a patient with acquired immunodeficiency syndrome-related complex. Arch Pathol Lab Med 114:376–378, 1990.

    CAS  PubMed  Google Scholar 

  • Schouten TJ, Hustinx TWJ, Scheres JMJC, et al: Malignant histiocytosis. Clinical and cytogenetic studies in a newborn and a child. Cancer 52:1229–1236, 1983.

    CAS  PubMed  Google Scholar 

  • Tubbs RR, Sheibani K, Sebek BA, et al: Malignant histiocytosis. Ultrastructural and imunocytochemical characterization. Arch Pathol Lab Med 104:26–29, 1980.

    CAS  PubMed  Google Scholar 

  • Vilpo JA, Klemi P, Lassila O, et al: Cytological and functional characterization of three cases of malignant histiocytosis. Cancer 46:1795–1801, 1980.

    CAS  PubMed  Google Scholar 

Langerhans’ Cell Histiocytosis (Histiocytosis X)

  • Bartosik J, Andersson A, Axelsson S, et al: Direct evidence for the cytomembrane derivation of Birbeck granules: The membrane-sandwich effect. Acta Derm Venereol (Stockh) 65:157–160, 1985.

    CAS  Google Scholar 

  • Basset F, Turiaf J: Identification par la microscopie electronique de particules de nature probablement virale dans le lesions granulomateuses d’une histiocytose “X” pulmonaire. CR Acad Sci [III] 261:3701, 1965.

    CAS  Google Scholar 

  • Birbeck MS, Breathnach AS, Everall JD: An electron microscopic study of basal melanocytes and high-level clear cells (Langerhans’ cells) in vitiligo. J Invest Dermatol 37:51–64, 1961.

    Google Scholar 

  • Bruno J, Tognetti A: Ultrastructural formation of Langerhans’ cell granules in a case of histiocytosis X [letter to the editor]. Ultrastruct Pathol 13:89–90, 1989.

    CAS  PubMed  Google Scholar 

  • Callihan TR: Langerhans’ cell histiocytosis (histiocytosis X). In Jaffe ES: Surgical Pathology of the Lymph Nodes and Related Organs, 2nd ed. Major Problems in Pathology, vol 16. WB Saunders, Philadelphia, 1995, 534–559.

    Google Scholar 

  • Case Records of the Massachusetts General Hospital, Case #40-1993. N Engl J Med 329:1108–1115, 1993.

    Google Scholar 

  • Dickersin GR: Electron microscopy of leukemias and lymphomas. Clin Lab Med 7(1):199–247, 1987.

    CAS  PubMed  Google Scholar 

  • Mierau GW, Favara BE, Brenman JM: Electron microscopy in histiocytosis X. Ultrastruct Pathol 3:137–142, 1982.

    CAS  PubMed  Google Scholar 

  • Lieberman PH, Jones CR, Steinman RM, et al: Langerhans cell (eosinophilic) granulomatosis. A clinicopathologic study encompassing 50 years. Am J Surg Pathol 20:519–552, 1996.

    Article  CAS  PubMed  Google Scholar 

  • Lukes RJ, Collins RD. Mononuclear phagocyte system neoplasms. In Hartman WH, ed: Atlas of Tumor Pathology. Tumors of the hematopoietic system, 2nd series, fasc 28. Washington, DC, Armed Forces Institute of Pathology, 1992, 273–304.

    Google Scholar 

  • Lukes RJ, Collins RD: Benign hematopoietic disorders that resemble neoplasms or may develop into neoplasms. In Atlas of Tumor Pathology. Tumors of the hematopoietic system, 2nd series, fasc 28. Washington, DC, Armed Forces Institute of Pathology, 1992, 396–399.

    Google Scholar 

  • Morales AR, Fine G, Horn RC, et al: Langerhans’ cells in a localized lesion of the eosinophilic granuloma type. Lab Invest 20:412–423, 1969.

    CAS  PubMed  Google Scholar 

  • Murphy GF, Harrist TJ, Bhan AK, et al: Distribution of cell surface antigens in histiocytosis X cells. Quantitative immuno-electron microscopy using monoclonal antibodies. Lab Invest 48:90–97, 1983.

    CAS  PubMed  Google Scholar 

  • Risdall RJ, Dehner LP, Duray P, et al: Histiocytosis X (Langerhans’ cell histiocytosis). Arch Pathol Lab Med 107:59–63, 1983.

    CAS  PubMed  Google Scholar 

  • Robb IA, Jimenez L, Carpenter BF: Birbeck granules or Birbeck junctions? Intercellular “zipperlike” lattice Junetions in eosinophilic granuloma of bone. Ultrastruct Pathol 16:423–428, 1992.

    CAS  PubMed  Google Scholar 

  • Sagebiel RW, Reed TH: Serial reconstruction of the characteristic granule of the Langerhans’ cell. J Cell Biol 36:595–602, 1968.

    Article  CAS  PubMed  Google Scholar 

  • Schuler G, Romani N, Stingl G, et al: Coated Langerhans’ cell granules in histiocytosis X cells. Ultrastruct Pathol 5:77–82, 1983.

    CAS  PubMed  Google Scholar 

  • Tornowski WM, Hashimoto K: Langerhans’ cell granules in histiocytosis X. The epidermal Langerhans’ cell as a macrophage. Arch Dermatol 96:298–304, 1967.

    Google Scholar 

Dendritic Cell Lesions

  • Chan JKC, Tsang WYW, Ng CS, et al: Follicular dendritic cell tumors of the oral cavity. Am J Surg Pathol 18:148–157, 1994.

    CAS  PubMed  Google Scholar 

  • Monda L, Warnke R, Rosai J: A primary lymph node malignancy with features suggestive of dendritic reticulum cell differentiation. A report of 4 cases. Am J Pathol 122:562–572, 1986.

    CAS  PubMed  Google Scholar 

  • Nakamura S, Hara K, Suchi T, et al: Interdigitating cell sarcoma. A morphologic, immunohistologic, and enzyme-histochemical study. Cancer 61:562–568, 1988.

    CAS  PubMed  Google Scholar 

  • Perez-Ordonez B, Erlandson RA, Rosai J: Follicular cell tumor. Report of 13 additional cases of a distinctive entity. Am J Surg Pathol 20:944–955, 1996.

    CAS  PubMed  Google Scholar 

  • Vasef MA, Zaatari GS, Chan WC, et al: Dendritic cell tumors associated with low-grade B-cell malignancies. Report of three cases. Am J Clin Pathol 104:696–701, 1995.

    CAS  PubMed  Google Scholar 

  • Weiss LM, Berry GJ, Dorfman RF, et al: Spindle cell neoplasms of lymph nodes of probable reticulum cell lineage. True reticulum cell carcinoma? Am J Surg Pathol 14:405–414, 1990.

    CAS  PubMed  Google Scholar 

Mastocytoma and Mastocytosis

  • Abraham EK, Augustine J, Amma S, et al: Malignant systemic mastocytosis. Ind J Cancer 29:192–197, 1992.

    CAS  Google Scholar 

  • Anstey A, Lowe DG, Kirby JD, et al: Familial mastocytosis: A clinical, immunophenotypic, light and electron microscopic study. Br J Dermatol 125:583–587, 1991.

    CAS  PubMed  Google Scholar 

  • Diebold J, Riviere O, Gosselin B, et al: Different patterns of spleen involvement in systemic and malignant mastocytosis. A histological and immunohistochemical study of three cases. Virchows Arch [A] 419:273–280, 1991.

    CAS  Google Scholar 

  • Galli SJ: New concepts about the mast cell. Semin Med Beth Israel Hosp 328:257–265, 1993.

    CAS  Google Scholar 

  • Horny HP, Rabenhorst G, Loffler H, et al: Solitary fibromastocytic tumor arising in an inguinal lymph node: The first description of a unique spindle cell tumor simulating mastocytosis. Mod Pathol 7:962–966, 1994.

    CAS  PubMed  Google Scholar 

  • Kawai S, Okamoto H: Giant mast cell granules in a solitary mastocytoma. Pediatr Dermatol 10:12–15, 1993.

    CAS  PubMed  Google Scholar 

  • Rottem M, Okada T, Goff JP, et al: Mast cells cultured from the peripheral blood of normal donors and patients with mastocytosis originate from a CD34+/Fc epsilon Rl-cell population. Blood 84:2489–2496, 1994.

    CAS  PubMed  Google Scholar 

  • Soter NA: The skin in mastocytosis [review]. J Invest Dermatol 96:32S–38S; discussion 38S–39S, 1991.

    Article  CAS  PubMed  Google Scholar 

  • Weidner N, Horan RF, Austen KF: Mast-cell phenotype in indolent forms of mastocytosis. Ultrastructural features, fluorescence detection of avidin binding, and immunofluorescent determination of chymase, tryptase, and carboxypeptidase. Am J Pathol 140:847–857, 1992.

    CAS  PubMed  Google Scholar 

  • Wood C, Sina B, Webster CG, et al: Fibrous mastocytoma in a patient with generalized cutaneous mastocytosis. J Cutan Pathol 19:128–133, 1992.

    CAS  PubMed  Google Scholar 

Download references

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2000 Springer-Verlag New York, Inc.

About this chapter

Cite this chapter

(2000). Large Cell Neoplasms. In: Dickersin, G.R. (eds) Diagnostic Electron Microscopy. Springer, New York, NY. https://doi.org/10.1007/0-387-21852-1_3

Download citation

  • DOI: https://doi.org/10.1007/0-387-21852-1_3

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-0-387-98388-2

  • Online ISBN: 978-0-387-21852-6

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics