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Laparoscopic Splenectomy

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Laparoscopic Surgery of the Abdomen
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Conclusion

Laparoscopic splenectomy should be considered the standard of care for patients who require splenectomy for ITP, hemolytic anemia, and other hematological disorders with primary splenic manifestations. Relative to open splenectomy, laparoscopic splenectomy appears to have equivalent clinical outcomes in terms of cure of the underlying disorder. However, LS results in less patient disability, shorter hospitalization, and probably less perioperative morbidity, although there are no prospective, randomized comparisons of the open and laparoscopic procedures. The cost of laparoscopic splenectomy to the health care institution may initially be higher, but medical cost differences will likely evolve in favor of the laparoscopic over the open procedure with increasing surgical experience. The indirect savings to society from reduced disability are significant but difficult to calculate.

Indications for LS are expanding based on the accrued experience of laparoscopic surgeons and the excellent outcomes to date. With continued advances in techniques and instrumentation, even patients with splenic trauma or massive splenomegaly may some day be managed laparoscopically.

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References

  1. Delaitre B, Maignien B, Icard P. Laparoscopic splenectomy. Br J Surg 1992;79:1334.

    PubMed  CAS  Google Scholar 

  2. Schwartz SI. Spleen. In: Schwartz SI, Shires GT, Spencer FC (eds) Spleen, 5th Ed. St. Louis: McGraw-Hill, 1989:1441–1457.

    Google Scholar 

  3. Katkhouda N, Hurwitz MB, Rivera RT, et al. Laparoscopic splenectomy: outcome and efficacy in 103 consecutive patients. Ann Surg 1998;228:568–578.

    Article  PubMed  CAS  Google Scholar 

  4. Michels N. The variational anatomy of the spleen and splenic artery. Am J Anat 1942;70:21–72.

    Article  Google Scholar 

  5. George J, El-Harake M, Raskob G. Chronic idiopathic thrombocytopenic purpura. N Engl J Med 1994;331:1207–1211.

    Article  PubMed  CAS  Google Scholar 

  6. Harold KL, Schlinkert RT, Mann DK, et al. Long-term results of laparoscopic splenectomy for immune thrombocytopenic purpura. Mayo Clin Proc 1999;74:37–39.

    Article  PubMed  CAS  Google Scholar 

  7. Meyer G, Wichmann MW, Rau HG, Hiller E, Schildberg FW. Laparoscopic splenectomy for idiopathic thrombocytopenic purpura. Surg Endosc 1998;12:1348–1352.

    Article  PubMed  CAS  Google Scholar 

  8. Tanoue K, Hashizume M, Morita M, et al. Results of laparoscopic splenectomy for immune thrombocytopenia purpura. Am J Surg 1999;177:222–226.

    Article  PubMed  CAS  Google Scholar 

  9. Lord R, Coleman M, Milliken S. Splenectomy for HIV-related immune thrombocytopenia. Arch Surg 1998;133: 205–210.

    Article  PubMed  CAS  Google Scholar 

  10. Tefferi A. Myelofibrosis with myeloid metaplasia. N Engl J Med 2000;342:1255–1265.

    Article  PubMed  CAS  Google Scholar 

  11. Rattner D, Ellman L, Warshaw A. Portal vein thrombosis after elective splenectomy. Arch Surg 1993;128:565–570.

    PubMed  CAS  Google Scholar 

  12. Emmermann A, Sornig C, Peiper M, Weh JH, Broelsch CE. Laparoscopic splenectomy: technique and results in a series of 27 cases. Surg Endosc 1995;9:924–927.

    PubMed  CAS  Google Scholar 

  13. Gigot JF, Legrand M, Cadiere GB. Is laparoscopic splenectomy a justified approach in hematologic disorders? Int Surg 1995;80:299–303.

    PubMed  CAS  Google Scholar 

  14. Bove T, Delvaux G, Van Eijkelenburg P, De Backer A, Willems G. Laparoscopic assisted surgery of the spleen: clinical experience in expanding indications. J Laparoendosc Surg 1996;6:213–217.

    PubMed  CAS  Google Scholar 

  15. Flowers JL, Lefor AT, Steers J, Heyman M, Graham SM, Imbembo A. Laparoscopic splenectomy in patients with hematologic diseases. Ann Surg 1996;224:19–28.

    Article  PubMed  CAS  Google Scholar 

  16. Tsiotos G, Schlinkert RT. Laparoscopic splenectomy for immune thrombocytopenic purpura. Arch Surg 1997;132: 642–646.

    PubMed  CAS  Google Scholar 

  17. Szold A, Sagi B, Merhav H, Klausner MM. Optimizing laparoscopic splenectomy: technical details and experience in 59 patients. Surg Endsoc 1998;12:1078–1081.

    Article  CAS  Google Scholar 

  18. Decker G, Millat B, Guillon F, Atger J, Linon M. Laparoscopic splenectomy for benign and malignant diseases: 35 consecutive cases. World J Surg 1998;22:62–68.

    Article  PubMed  CAS  Google Scholar 

  19. Walsh R, Heniford B. Laparoscopic splenectomy for non-Hodgkin’s lymphoma. J Surg Oncol 1999;70:116–121.

    Article  PubMed  CAS  Google Scholar 

  20. Brody FJ, Chekan EG, Pappas TN. Conversion factors for laparoscopic splenectomy for immune thrombocytopenic purpura. Surg Endosc 1999;13:789–791.

    Article  PubMed  CAS  Google Scholar 

  21. Stanton C. Laparoscopic splenectomy for idiopathic thrombocytopenic purpura. Surg Endosc 1999;13:1083–1086.

    Article  PubMed  CAS  Google Scholar 

  22. Gossot D, Fritsch S, Celerier M. Laparoscopic splenectomy: optimal vascular control using the lateral approach and ultrasonic dissection. Surg Endosc 1999;13:21–25.

    Article  PubMed  CAS  Google Scholar 

  23. Trias M, Targarona E, Espert J, et al. Impact of hematological diagnosis on early and late outcome after laparoscopic splenectomy. Surg Endosc 2000;14:556–560.

    Article  PubMed  CAS  Google Scholar 

  24. Baccarani U, Carroll BJ, Hiatt JR, et al. Comparison of laparoscopic and open staging in Hodgkin disease. Arch Surg 1998;133:517–522.

    Article  PubMed  CAS  Google Scholar 

  25. Berman RS, Yahanda AM, Mansfield PF, et al. Laparoscopic splenectomy in patients with hematologic malignancies. Am J Surg 1999;178:530–536.

    Article  PubMed  CAS  Google Scholar 

  26. Targarona E, Trias M. Laparoscopic treatment of splenic injuries. Semin Laparosc Surg 1996;3:44–49.

    PubMed  Google Scholar 

  27. Park AE, Birgisson G, Mastrangelo MJ, Marcaccio MM, Witzke DB. Laparoscopic splenectomy: outcomes and lessons learned from over 200 cases. Surgery (St. Louis) 2000;128:660–667.

    Article  CAS  Google Scholar 

  28. Targarona EM, Espert JJ, Cerdain G. Effect of spleen size on splenectomy outcome: a comparison of open and laparoscopic surgery. Surg Endosc 1999;13:559–562.

    Article  PubMed  CAS  Google Scholar 

  29. Schlachta CM, Poulin EC, Mamazza J. Laparoscopic splenectomy for hematologic malignancies. Ann Surg 1998; 228:35–39.

    Article  Google Scholar 

  30. Friedman RL, Fallas MJ, Carroll BJ, Hiatt JR, Phillips EH. Laparoscopic splenectomy for ITP: the gold standard. Surg Endosc 1996;10:991–995.

    Article  PubMed  CAS  Google Scholar 

  31. Watson DI, Coventry BJ, Chin T, Gil PG, Malycha P. Laparoscopic versus open splenectomy for immune thrombocytopenic purpura. Surgery (St. Louis) 1997;121:18–22.

    Article  CAS  Google Scholar 

  32. Marassi A, Vignali A, Zuliani W, Biguzi E, Bergamo CGL, Di Carlo V. Splenectomy for idiopathic thrombocytopenic purpura. Surg Endosc 1999;13:17–20.

    Article  PubMed  CAS  Google Scholar 

  33. Shimomatsuya T, Horiuchi T. Laparoscopic splenectomy for treatment of patients with idiopathic thrombocytopenic purpura. Comparison with open splenectomy. Surg Endosc 1999;13:563–566.

    Article  PubMed  CAS  Google Scholar 

  34. Trias M, Targarona EM, Espert JJ, Balague C. Laparoscopic surgery for splenic disorders. Surg Endosc 1998;12:66–72.

    Article  PubMed  CAS  Google Scholar 

  35. Glasgow RE, Yee LF, Mulvihill SJ. Laparoscopic splenectomy: the emerging standard. Surg Endosc 1997;11:108–112.

    Article  PubMed  CAS  Google Scholar 

  36. Rhodes M, Rudd M, O’Rourke N, Nathanson L, Fielding G. Laparoscopic splenectomy in patients with hematologic disorders. Ann Surg 1995;222:43–46.

    PubMed  CAS  Google Scholar 

  37. Brunt LM, Quasebarth MA, Whitman ED. Comparative analysis of laparoscopic versus open splenectomy. Am J Surg 1996;172:596–601.

    Article  PubMed  CAS  Google Scholar 

  38. Yee LF, Carvajal SH, de Lorimier AA, Mulvihill SJ. Laparoscopic splenectomy. The initial experience at University of California, San Francisco. Arch Surg 1995;130:874–879.

    CAS  Google Scholar 

  39. Diaz J, Eisenstat M, Chung R. A case-controlled study of laparoscopic splenectomy. Am J Surg 1997;173:348–350.

    Article  PubMed  CAS  Google Scholar 

  40. Friedman R, Hiatt J, Korman JFK, Cymerman J, Phillips E. Laparoscopic or open splenectomy for hematologic disease: which approach is superior? J Am Coll Surg 1997;185:49–54.

    Article  PubMed  CAS  Google Scholar 

  41. Donini A, Baccarani U, Terrosu G, et al. Laparoscopic vs open splenectomy in the management of hematologic diseases. Surg Endosc 1999;13:1220–1225.

    Article  PubMed  CAS  Google Scholar 

  42. Janu PG, Rogers DA, Love TE. A comparison of laparoscopic and traditional open splenectomy in childhood. J Pediatr Surg 1996;31:109–114.

    Article  PubMed  CAS  Google Scholar 

  43. Smith CD, Meyer TA, Goretsky MJ, Hyamus D, Michetle FA, Fegelman EJ. Laparoscopic splenectomy by the lateral approach: a safe and effective alternative approach to open splenectomy for hematologic diseases. Surgery (St. Louis) 1996;120:789–794.

    CAS  Google Scholar 

  44. Rescorla FJ, Breitfeld PP, West KW, Williams D, Engum SA, Grosfeld JL. A case controlled comparison of open and laparoscopic splenectomy in children. Surgery (St. Louis) 1998;124:670–676.

    Article  CAS  Google Scholar 

  45. Park A, Marcaccio M, Sternbach M, Witzke D, Fitzgerald P. Laparoscopic vs open splenectomy. Arch Surg 1999;134: 1263–1269.

    Article  PubMed  CAS  Google Scholar 

  46. Zamir O, Szold A, Matzner Y, et al. Laparoscopic splenectomy for immune thrombocytopenic purpura. J Laparoendosc Surg 1996;6:301–304.

    PubMed  CAS  Google Scholar 

  47. Katkhouda N, Waldrep DJ, Feinstein D, Soliman H, Stain SC, Artega AE. Unresolved issues in laparoscopic splenectomy. Am J Surg 1996;172:585–590.

    Article  PubMed  CAS  Google Scholar 

  48. Lozano-Salazar R.R., Herrera MF, Vargas-Vorachkova F, Lopez-Karpovitch X. Laparoscopic versus open splenectomy for immune thrombocytopenic purpura. Am J Surg 1998;176:366–369.

    Article  PubMed  CAS  Google Scholar 

  49. Schlinkert RT, Teotia SS. Laparoscopic splenectomy. Arch Surg 1999;134:99–103.

    Article  PubMed  CAS  Google Scholar 

  50. Park A, Gagner M, Pomp A. The lateral approach to laparoscopic splenectomy. Am J Surg 1997;173:126–130.

    Article  PubMed  CAS  Google Scholar 

  51. Hashizume M, Sugimachi K, Kitano S, et al. Laparoscopic splenectomy. Am J Surg 1994;167:611–614.

    Article  PubMed  CAS  Google Scholar 

  52. Trias M, Targarona EM, Balague C. Laparoscopic splenectomy: an evolving technique. A comparison between anterior and lateral approaches. Surg Endosc 1996;10:389–392.

    Article  PubMed  CAS  Google Scholar 

  53. Saldinger PF, Matthews JB, Mowschenson PM, Hodin RA. Stapled laparoscopic splenectomy: initial experience. J Am Coll Surg 1996;182:459–461.

    PubMed  CAS  Google Scholar 

  54. Delaitre B. Laparoscopic splenectomy: the “hanged spleen?technique. Surg Endosc 1995;9:528–529.

    Article  PubMed  CAS  Google Scholar 

  55. Lefor AT, Melvin WS, Bailey RW, Flowers JL. Laparoscopic splenectomy in the managment of immune thrombocytopenia purpura. Surgery (St. Louis) 1993;114:613–618.

    CAS  Google Scholar 

  56. Richardson WS, Smith CD, Branum GD, Hunter JG. Leaning spleen: a new approach to laparoscopic splenectomy. J Am Coll Surg 1997;185:412–415.

    Article  PubMed  CAS  Google Scholar 

  57. Dexter SPL, Martin IG, Alao D, Norfolk DR, McMahon MJ. Laparoscopic splenectomy: the suspended pedicle technique. Surg Endosc 1996;10:393–396.

    Article  PubMed  CAS  Google Scholar 

  58. Gigot JF, Jamar F, Ferrant A, et al. Inadequate detection of accessory spleens and splenosis with laparoscopic splenectomy. Surg Endosc 1998;12:101–103.

    Article  PubMed  CAS  Google Scholar 

  59. Laycock WS, Hunter JG. New technology for the division of short gastric vessels during laparoscopic Nissen fundoplication: a prospective randomized trial. Surg Endosc 1996; 10:71–73.

    Article  PubMed  CAS  Google Scholar 

  60. Rothenberg SS. Laparoscopic splenectomy using the harmonic scalpel. J Laparendosc Surg 1996;6S:61–63.

    Google Scholar 

  61. Miles WFA, Greig JD, Wilson RG, Nixon SJ. Technique of laparoscopic splenectomy with a powered vascular linear stapler. Br J Surg 1996;83:1212–1214.

    Article  PubMed  CAS  Google Scholar 

  62. Horowitz J, Smith JL, Wever TK, Rodriguez-Bigas MA, Petrelli NJ. Postoperative complications after splenectomy for hematologic malignancies. Ann Surg 1996;223:290–296.

    Article  PubMed  CAS  Google Scholar 

  63. Nelson EW, Mone MC. Splenectomy in high-risk patients with splenomegaly. Am J Surg 1999;178:581–586.

    Article  PubMed  CAS  Google Scholar 

  64. Terrosu G, Donini A, Baccarani U, et al. Laparoscopic versus open splenectomy in the management of splenomegaly: our preliminary experience. Surgery (St. Louis) 1998;124:839–843.

    CAS  Google Scholar 

  65. Targarona E, Espert J, Balague C, et al. Residual splenic function after laparoscopic splenectomy. Arch Surg 1998; 133:56–60.

    Article  PubMed  CAS  Google Scholar 

  66. Morgenstern L, Skandalakis JE. Anatomy and embryology of the spleen. In: Hiatt JR, Phillips EH, Morgenstern L (eds) Surgical Diseases of the Spleen. Berlin: Springer, 1997: 15–24.

    Google Scholar 

  67. Southern Surgeons’ Club Study Group. Handoscopic surgery: a prospective multicenter trial of a minimally invasive technique for complex abdominal surgery. Arch Surg 1999;134:477–485.

    Article  Google Scholar 

  68. Pratt C, Anderson T, Demeure MJ. Hand-assisted laparoscopic splenectomy: retained benefits of laparoscopic splenectomy over open splenectomy. Presented at the SAGES 2000 meeting in Atlanta, GA.

    Google Scholar 

  69. Matthews BD, Backus CL, Walsh RM, Pratt BL, Greene FL, Heniford BT. Laparoscopic versus hand-assisted splenectomy in patients with massive splenomegaly. Presented at the SAGES 2000 meeting, Atlanta, GA.

    Google Scholar 

  70. Yood SM, Kelly J, Sandor A, Roll S, Cohen R, Litwin DEM. Hand-assisted laparoscopic splenectomy for splenomegaly. Presented at the SAGES 2000 meeting, Atlanta, GA.

    Google Scholar 

  71. Targarona E, Espert J, Bombuy E, et al. Complications of laparoscopic splenectomy. Arch Surg 2000;135:1137–1140.

    Article  PubMed  CAS  Google Scholar 

  72. Navarro R, Korman J, Phillips E. Complications of laparoscopic splenectomy. Semin Laparosc Surg 1997;4:182–189.

    Google Scholar 

  73. Szold A, Kamat M, Nadu A. Laparoscopic accessory splenectomy for recurrent idiopathic thrombocytopenic purpura and hemolytic anemia. Surg Endosc 2000;14:761–763.

    Article  PubMed  CAS  Google Scholar 

  74. Schilling RF. Estimating the risk of sepsis after splenectomy for hereditary spherocytosis. Ann Intern Med 1995;122: 187–188.

    PubMed  CAS  Google Scholar 

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Whitman, E.D., Brunt, L.M. (2004). Laparoscopic Splenectomy. In: MacFadyen, B.V., et al. Laparoscopic Surgery of the Abdomen. Springer, New York, NY. https://doi.org/10.1007/0-387-21780-0_27

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  • DOI: https://doi.org/10.1007/0-387-21780-0_27

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