Conclusions
Patients with SCC due to metastatic disease of the spine must be simultaneously evaluated with regard to neurologic impairment, stability of the spine, and tumor type. A multidisciplinary approach is required for these patients including an internist, medical oncologist, radiation oncologist, and spinal surgeon. Compressive tumor extension can be treated effectively by radiotherapy for lesions that are radiosensitive, but radiotherapy cannot reverse a neurologic deficit if the SCC is a result of instability, vertebral collapse, or kyphosis. Spinal lesions with impending instability or current instability require spinal stabilization. The goals of surgery are to maintain or restore neurologic function and spinal stability, relieve pain, and maintain an independent quality of life. If the patient is medically able to undergo spinal surgery and has a life expectancy of 3 months or more, surgical intervention should be strongly considered.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Similar content being viewed by others
References
DeVita VT, Mauch PM, Harris NL. Hodgkin’s disease. In: DeVita VT, Hellman S, Rosenberg SA (eds) Cancer: Principles and Practice of Oncology, 5th ed. Philadelphia: Lippincott-Raven, 1997:2242–2284.
Landis SH, Murray T, Bolden S, Wingo PA. Cancer statistics, 1998. CA Cancer J Clin 1998;48:6–29.
Brauninger A, Hansmann ML, Strickler JG, et al. Identification of common germinal-center B-cell precursors in two patients with both Hodgkin’s disease and non-Hodgkin’s lymphoma. N Engl J Med 1999;340:1239–1247.
Medeiros LJ, Greiner TC. Hodgkin’s disease. Cancer 1995;75:357–369.
Das DK, Gupta SK, Datta BN, Sharma SC. Fine needle aspiration cytodiagnosis of Hodgkin’s disease and its subtypes. I. Scope and limitations. Acta Cytol 1990;34:329–336.
Fulciniti F, Vetrani A, Zeppa P, et al. Hodgkin’s disease: diagnostic accuracy of fine needle aspiration; a report based on 62 consecutive cases. Cytopathology 1994;5:226–233.
Stewart CJ, Duncan JA, Farquharson M, Richmond J. Fine needle aspiration cytology diagnosis of malignant lymphoma and reactive lymphoid hyperplasia. J Clin Pathol 1998;51:197–203.
Das DK, Gupta SK. Fine needle aspiration cytodiagnosis of Hodgkin’s disease and its subtypes. II. Subtyping by differential cell counts. Acta Cytol 1990;34:337–341.
Pappa VI, Hussain HK, Reznek RH, et al. Role of image-guided core-needle biopsy in the management of patients with lymphoma. J Clin Oncol 1996;14:2427–2430.
Ben-Yehuda D, Polliack A, Okon E, et al. Image-guided core-needle biopsy in malignant lymphoma: experience with 100 patients that suggests the technique is reliable. J Clin Oncol 1996;14:2431–2434.
Mann GB, Conlon KC, LaQuaglia M, et al. Emerging role of laparoscopy in the diagnosis of lymphoma. J Clin Oncol 1998;16:1909–1915.
Lister TA, Crowther D, Sutcliffe SB, et al. Report of a committee convened to discuss the evaluation and staging of patients with Hodgkin’s disease: Cotswolds meeting. J Clin Oncol 1989;7:1630–1636. Erratum. J Clin Oncol 1990;8:1602.
AJCC. Hodgkin’s disease. In: AJCC Cancer Staging Handbook, 5th ed. Philadelphia: Lippincott Williams & Wilkins, 1998;259–261.
Breuer CK, Tarbell NJ, Mauch PM, et al. The importance of staging laparotomy in pediatric Hodgkin’s disease. J Pediatr Surg 1994;29:1085–1089.
Yahalom J, Straus D. Hodgkin’s disease. In: Pazdur R, Coia LR, Hoskins WJ, Wagman LD (eds) Cancer Management: A Multidisciplinary Approach, 3rd ed. Melville, NY: PRR, 1999.
Leibenhaut MH, Hoppe RT, Efron B, et al. Prognostic indicators of laparotomy findings in clinical stage I-II supradiaphragmatic Hodgkin’s disease. J Clin Oncol 1989;7:81–91.
Cosset JM, Henry-Amar M, Meerwaldt JH, et al. The EORTC trials for limited stage Hodgkin’s disease: the EORTC Lymphoma Cooperative Group. Eur J Cancer 1992;11:1847–1850.
Rock DB, Murray KJ, Schultz CJ, et al. Stage I and II Hodgkin’s disease in the pediatric population: long-term follow-up of patients staged predominantly clinically. Am J Clin Oncol 1996;19:174–178.
Jockovich M, Mendenhall NP, Sombeck MD, et al. Long-term complications of laparotomy in Hodgkin’s disease. Ann Surg 1994;219:615–621.
Baccarani U, Carroll BJ, Hiatt JR, et al. Comparison of laparoscopic and open staging in Hodgkin disease. Arch Surg 1998;133:517–521.
Lefor AT, Flowers JL, Heyman MR. Laparoscopic staging of Hodgkin’s disease. Surg Oncol 1993;2:217–220.
Mason MD, Law M, Ashley S, et al. Infradiaphragmatic Hodgkin’s disease. Eur J Cancer 1992;11:1851–1852.
Hoppe R, Winter J. Practice guidelines: Hodgkin’s disease. Presented at the National Comprehensive Cancer Network, 3rd Annual Conference, Ft. Lauderdale, FL, 1998.
Aragon de la Cruz G, Cardenes H, Otero J, et al. Individual risk of abdominal disease in patients with stages I and II supradiaphragmatic Hodgkin’s disease: a rule index based on 341 laparotomized patients. Cancer 1989;63:1799–1803.
Mauch P, Larson D, Osteen R, et al. Prognostic factors for positive surgical staging in patients with Hodgkin’s disease. J Clin Oncol 1990;8:257–265.
Bhatia S, Robison LL, Oberlin O, et al. Breast cancer and other second neoplasms after childhood Hodgkin’s disease. N Engl J Med 1996;334:745–751.
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2003 Springer-Verlag New York, Inc.
About this chapter
Cite this chapter
Lai, L.L., Schwarz, R.E. (2003). Hodgkin’s Disease. In: Saclarides, T.J., Millikan, K.W., Godellas, C.V. (eds) Surgical Oncology. Springer, New York, NY. https://doi.org/10.1007/0-387-21701-0_58
Download citation
DOI: https://doi.org/10.1007/0-387-21701-0_58
Publisher Name: Springer, New York, NY
Print ISBN: 978-0-387-95201-7
Online ISBN: 978-0-387-21701-7
eBook Packages: Springer Book Archive