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Retroperitoneal Sarcomas

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Surgical Oncology
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Conclusions

Retroperitoneal sarcomas comprise a rare, heterogeneous group of neoplasms. Routine workup should include the medical history, a physical examination, and helical CT of the abdomen and pelvis with selective use of MRI and preoperative tissue sampling. The primary treatment is complete surgical resection with a rim of normal tissue. The role of adjuvant therapy is evolving and at present should not be used outside the investigational setting.

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References

  1. Clark JA, Tepper JE. Role of radiation therapy in retroperitoneal sarcomas. Oncology 1996;10:1867–1872.

    CAS  PubMed  Google Scholar 

  2. Boring CC, Squires TS, Tong T, Montgomery S. Cancer statistics, 1994. CA Cancer J Clin 1994;44:7–26.

    CAS  PubMed  Google Scholar 

  3. James T, Adams M. Abdominal wall, omentum, mesentery and retroperitoneum. In: Schwartz SI (ed) Principles of Surgery. New York: McGraw-Hill, 1994;1511–1516.

    Google Scholar 

  4. Conlon KC, Brennan MF. Soft tissue sarcoma. In: Murphy, Lawrence, Lenhard (eds) Clinical Oncology. Atlanta: American Cancer Society, 1996; 436–450.

    Google Scholar 

  5. Lewis JJ, Leung D, Woodruff JM, Brennan MF. Retroperitoneal sarcoma: analysis of 500 patients treated and followed at a single institution. Ann Surg 1998;228:355–365.

    Article  CAS  PubMed  Google Scholar 

  6. Cody HS, Turnbull AD, Fortner JG, Hajdu SI. The continuing challenge of retroperitoneal sarcomas. Cancer 1981;47:2148–2152.

    Google Scholar 

  7. Storm FK, Eilber FR, Mira J, Morton DL. Retroperitoneal sarcoma: a reappraisal of treatment. J Surg Oncol 1981;17:1–17.

    CAS  PubMed  Google Scholar 

  8. Kilkenny JW, Bland KI, Copeland EM. Retroperitoneal sarcoma: the University of Florida experience. J Am Coll Surg 1996;182:329–339.

    PubMed  Google Scholar 

  9. Singer S, Corson J, Demetri GD, et al. Prognostic factors predictive of survival for truncal and retroperitoneal soft tissue sarcoma. Ann Surg 1995;221:185–195.

    CAS  Google Scholar 

  10. Alvarenga JC, Ball ABS, Fisher C, et al. Limitations of surgery in the treatment of retroperitoneal sarcoma. Br J Surg 1991;78:912–916.

    CAS  PubMed  Google Scholar 

  11. Karakousis CD, Gerstenbluth R, Kontzoglou K, Driscoll D. Retroperitoneal sarcomas and their management. Arch Surg 1995;130:1105–1109.

    Google Scholar 

  12. Brennan MF, Casper EF, Harrison LB. Soft tissue sarcoma. In: Devita VT, Hellman S, Rosenberg RA (eds) Cancer: Principles and Practice of Oncology. Philadelphia: Lippincott-Raven, 1997;1769–1788.

    Google Scholar 

  13. Varma DG, Jackson EF, Pollock RE, Benjamin RS. Soft tissue sarcoma of the extremities: MR appearance of post treatment changes and local recurrences. Magn Reson Imaging Clin N Am 1995;3:695–712.

    CAS  PubMed  Google Scholar 

  14. Kole AC, Nieweg OE, Van Ginkel RJ, et al. Detection of local recurrence of soft tissue sarcoma with positron emission tomography using [10F]fluorodeoxyglucose. Ann Surg Oncol 1997;4:57–63.

    Article  CAS  PubMed  Google Scholar 

  15. Miraldi F, Adler LP, Faulhaber P. PET imaging in soft tissue sarcomas. Cancer Treat Res 1997;91:51–64.

    CAS  PubMed  Google Scholar 

  16. Beahrs OH, Henson DE, Hutter RVP, Kennedy BJ (eds) American Joint Committee on Cancer Manual for Staging of Cancer, 5th ed. Philadelphia: Lippincott, 1997;149–156.

    Google Scholar 

  17. Gaynor JJ, Tan CC, Casper ES, et al. Refinement of clinicopathologic staging for localized soft tissue sarcoma of the extremity: a study of 423 adults. J Clin Oncol 1992;10:1317–1329.

    CAS  PubMed  Google Scholar 

  18. Jaques DP, Coit DG, Hajdu SI, Brennan AF. Management of primary and recurrent soft tissue sarcoma of the retroperitoneum. Ann Surg 1990;212:51–59.

    Article  CAS  PubMed  Google Scholar 

  19. McGrath PC, Neifeld JP, Lawrence W Jr, et al. Improved survival following complete excision of retroperitoneal sarcomas. Ann Surg 1984;200:200–204.

    CAS  PubMed  Google Scholar 

  20. Dalton RR, Donohue JH, Mucha P Jr, et al. Management of retroperitoneal sarcomas. Surgery 1989;106:725–733.

    CAS  PubMed  Google Scholar 

  21. Senio G, Tenchini P, Nifosi F, Jacono C. Surgical strategy for primary retroperitoneal tumors. Br J Surg 1989;76:385–389.

    Google Scholar 

  22. Russo P, Kim Y, Ravindram S, et al. Nephrectomy during operative management of retroperitoneal sarcoma. Ann Surg Oncol 1997;4:421–424.

    Article  CAS  PubMed  Google Scholar 

  23. Mingoli A, Sapienza P, Cavallaro A, et al. The effect of extent of caval resection in the treatment of inferior vena cava leiomyosarcoma. Anticancer Res 1997;17:3877–3881.

    CAS  PubMed  Google Scholar 

  24. Barkley HT Jr, Martin RG, Romsdahl MM, et al. Treatment of soft tissue sarcoma by preoperative irradiation and conservative surgical resection. Int J Radiat Oncol Biol Phys 1988;14:693–700.

    PubMed  Google Scholar 

  25. Brant TA, Parsons JT, Marcus RB Jr, et al. Preoperative irradiation for soft tissue sarcomas of the trunk and extremities in adults. Int J Radiat Oncol Biol Phys 1990;19:899–906.

    CAS  PubMed  Google Scholar 

  26. Suit HD, Mankin HJ, Schiller AL. Results of treatment of sarcoma of soft tissue radiation and surgery at Massachusetts General Hospital. Cancer Treat Symp 1985;3:33–36.

    Google Scholar 

  27. Suit HD, Mankin HJ, Wood W, et al. Preoperative, intraoperative, and postoperative radiation in the treatment of primary soft tissue sarcoma. Cancer 1985;55:2659–2669.

    CAS  PubMed  Google Scholar 

  28. Bose B. Primary malignant retroperitoneal tumors: analysis of 30 cases. Can J Surg 1979;22:215–221.

    CAS  PubMed  Google Scholar 

  29. Harrison LB, Gutierrez E, Fisher JJ. Retroperitoneal sarcoma: the Yale experience and a review of the literature. J Surg Oncol 1986;32:159–165.

    CAS  PubMed  Google Scholar 

  30. Cody HS, Turnbull AD, Fortner JG, et al. The continuing challenge of retroperitoneal sarcomas. Cancer 1981;47:2147–2154.

    PubMed  Google Scholar 

  31. Sondak VK, Robertson JM, Sussman JJ, et al. Preoperative idoxuridine and radiation for large soft tissue sarcomas: clinical results with five year follow up. Ann Surg Oncol 1998;5:106–112.

    Article  CAS  PubMed  Google Scholar 

  32. Glenn J, Sindelar WF, Kinsella T. Results of multimodality therapy of resectable soft tissue sarcomas of the retroperitoneum. Surgery 1985;97:316–325.

    CAS  PubMed  Google Scholar 

  33. Sindelar WF, Kinsella TJ, Chen PW, et al. Intraoperative electron beam radiotherapy in retroperitoneal sarcomas: results of a prospective randomized clinical trial. Arch Surg 1993;128:402–407.

    CAS  PubMed  Google Scholar 

  34. Willet CG, Suit HD, Tepper JE, et al. Intraoperative electron beam radiation therapy for retroperitoneal soft tissue sarcoma. Cancer 1991;68:278–284.

    Google Scholar 

  35. Bui NB, Maree D, Coindree JM, et al. First results of a prospective randomized study of CYVADIC adjuvant chemotherapy in adults with operable high risk soft tissue sarcoma. Proc Am Soc Clin Oncol 1989;8:318.

    Google Scholar 

  36. Picci P, Bacci G, Gherlizoni F, et al. Results of randomized trial for the treatment of localized soft tissue tumors of the extremities in adult patients. In: Ryan JR, Baher LO (eds) Recent Concepts in Sarcoma Treatment. Amsterdom: Kluwer, 1988;144–148.

    Google Scholar 

  37. Sarcoma Meta-Analysis Collaboration. Adjuvant chemotherapy for localized resectable soft-tissue sarcoma of adults: meta-analysis of individual data. Lancet 1997;350:1647–1654.

    Article  Google Scholar 

  38. Karakousis CP, Velez AF, Gerstenbluth R, et al. Resectability and survival in retroperitoneal sarcomas. Ann Surg Oncol 1996;3:150–158.

    Article  CAS  PubMed  Google Scholar 

  39. Trojani M, Contesso G, Coindre JM, et al. Soft-tissue sarcomas of adults; study of pathological prognostic variables and definition of histopathological grading system. Int J Cancer 1984;33:37–42.

    CAS  PubMed  Google Scholar 

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Porter, G.A., Feig, B.W. (2003). Retroperitoneal Sarcomas. In: Saclarides, T.J., Millikan, K.W., Godellas, C.V. (eds) Surgical Oncology. Springer, New York, NY. https://doi.org/10.1007/0-387-21701-0_42

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  • DOI: https://doi.org/10.1007/0-387-21701-0_42

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-0-387-95201-7

  • Online ISBN: 978-0-387-21701-7

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