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Surgical Oncology pp 162–175Cite as

Non-Small Cell Cancer of the Lung

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Conclusions

Resection is the accepted treatment for patients with stage I or II lung cancer; unfortunately, only 25% of patients fall into this category. Following resection, adjuvant therapy has no proven benefit for stage I or II patients. If stage IIIA (N2) disease is suspected on clinical grounds (CT scan, PET scan) and is confirmed histologically (needle biopsy or mediastinoscopy), initial surgery is generally contraindicated. Instead, chemotherapy and radiation are administered to downstage the lesion and potentially render it resectable. If unsuspected, pathologic stage IIIA (N2) disease is discovered following thoracotomy and lobectomy, postoperative irradiation and chemotherapy have proven benefit in terms of prolonging disease-free survival. Stage IIIB disease without N3 involvement may be treated first with chemotherapy and radiation followed by surgery, depending on tumor response. Most surgeons consider N3 disease a sign of inoperability.

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Authors
  1. William H. Warren
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  2. Timothy W. James
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Editor information

Editors and Affiliations

  1. Rush Medical College, Chicago, IL, 60612, USA

    Theodore J. Saclarides M.D. (Professor of Surgery, Head), Keith W. Millikan M.D. (Associate Professor of Surgery, Director of Undergraduate Surgical Education, Director) & Constantine V. Godellas M.D. (Associate Professor of Surgery, Academic Program Coordinator) (Professor of Surgery, Head),  (Associate Professor of Surgery, Director of Undergraduate Surgical Education, Director) &  (Associate Professor of Surgery, Academic Program Coordinator)

  2. Section of Colon and Rectal Surgery Department of General Surgery, Rush-Presbyterian-St. Luke’s Medical Center, Chicago, IL, 60612, USA

    Theodore J. Saclarides M.D. (Professor of Surgery, Head) (Professor of Surgery, Head)

  3. Nutrition Consultation Service Department of General Surgery, Rush-Presbyterian-St. Luke’s Medical Center, Chicago, IL, 60612, USA

    Keith W. Millikan M.D. (Associate Professor of Surgery, Director of Undergraduate Surgical Education, Director) (Associate Professor of Surgery, Director of Undergraduate Surgical Education, Director)

  4. Department of General Surgery, Rush-Presbyterian-St. Luke’s Medical Center, Chicago, IL, 60612, USA

    Constantine V. Godellas M.D. (Associate Professor of Surgery, Academic Program Coordinator) (Associate Professor of Surgery, Academic Program Coordinator)

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© 2003 Springer-Verlag New York, Inc.

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Warren, W.H., James, T.W. (2003). Non-Small Cell Cancer of the Lung. In: Saclarides, T.J., Millikan, K.W., Godellas, C.V. (eds) Surgical Oncology. Springer, New York, NY. https://doi.org/10.1007/0-387-21701-0_19

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  • DOI: https://doi.org/10.1007/0-387-21701-0_19

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-0-387-95201-7

  • Online ISBN: 978-0-387-21701-7

  • eBook Packages: Springer Book Archive

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