Skip to main content
SpringerLink
Log in

Transduodenal Local Resection for Periampullary Neoplasms

  • Chapter
Pancreatic Cancer

Part of the book series: M. D. Anderson Solid Tumor Oncology Series ((MDA))

Conclusion

Local resection of the ampulla is an appropriate form of therapy in the treatment of small benign ampullary neoplasms. This procedure appears to be less morbid than more radical procedures including pancreaticoduodenectomy, although the latter is clearly indicated in fit patients with advanced malignant processes or large benign tumors where reimplantation of the ducts is not technically feasible. Patients with invasive carcinoma who are not medically fit for pancreaticoduodenectomy may be considered for local resection. Patients with small, well-differentiated neuroendocrine tumors may also be candidates for local resection in the absence of known or suspected metastatic disease, although the data to support this are limited.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Halsted W. Contributions to the surgery of the bile passages, especially of the common bile duct. Boston Med Surg J. 1899;141.

    Google Scholar 

  2. Seifert E, Schulte F, Stolte M. Adenoma and carcinoma of the duodenum and papilla of Vater: a clinicopathologic study. Am J Gastroenterol. 1991;87:37–43.

    Google Scholar 

  3. Perzin K, Bridge M. Adenomas of the small intestine: a clinicopathologic review of 51 cases and a study of their relationship to carcinoma. Cancer. 1981;48:799–819.

    CAS  PubMed  Google Scholar 

  4. Kozuka S, Tsubone M, Yamaguchi A, et al. Adenomatous residue in cancerous papilla of Vater. Gut. 1981;22:1031–1034.

    CAS  PubMed  Google Scholar 

  5. Clary B, Tyler D, Dematos P, Gottfried M, Pappas T. Local ampullary resection with careful intraoperative frozen section evaluation for presumed benign ampullary neoplasms. Surgery. 2000;127:628–633.

    Article  CAS  PubMed  Google Scholar 

  6. Burke C, Beck G, Church J, van Stolk R. The natural history of untreated duodenal and ampullary adenomas in patients with familial adenomatous polyposis followed in an endoscopic surveillance program. Gastrointest Endosc. 1994;49:358–364.

    Google Scholar 

  7. Bulow S, Alm T, Fausa O, Hultcrantz R, Jarvinen J, Vasen H. Duodenal adenomatosis in familial adenomatous polyposis. Int J Colorectal Dis. 1995;10:43–46.

    CAS  PubMed  Google Scholar 

  8. Domizio P, Talbot I, Spigelman A, Williams C, Phillips R. Upper gastrointestinal pathology in familial adenomatous polyposis: results from a prospective study of 102 patients. J Clin Pathol. 1990;43:738–743.

    CAS  PubMed  Google Scholar 

  9. Church J, McGannon E, Hull-Boiner S, Jagelman D, Sivak M, van Stolk R. Upper gastrointestinal polyps in familial adenomatous polyposis. Dis Colon Rectum. 1992;35:1170–1173.

    Article  CAS  PubMed  Google Scholar 

  10. Howe J, Klimstra D, Moccia R, Conlon K. Brenan M. Factors predictive of survival in ampullary carcinoma. Ann Surg. 1998;228:87–94.

    Article  CAS  PubMed  Google Scholar 

  11. Yeo C, Sohn T, Cameron J, Hruban R, Lillemoe K, Pitt H. Periampullary adenocarcinoma: analysis of 5-year survivors. Ann Surg. 1998;227:821–831.

    Article  CAS  PubMed  Google Scholar 

  12. Beger H, Treitschke F, Gansauge F, Harada N, Hiki N, Mattfeldt T. Tumor of the ampulla of Vater. Arch Surg. 1999;134:526–532.

    CAS  PubMed  Google Scholar 

  13. Roder J, Schneider P, Stein H, Siewert J. Number of lymph node metastases is significantly associated with survival in patients with radically resected carcinoma of the ampulla of Vater. Br J Surg. 1995;82:1693–1696.

    CAS  PubMed  Google Scholar 

  14. Yamaguchi K, Enjoji M. Carcinoma of the ampulla of Vater: a clinicopathologic study and pathologic staging of 109 cases of carcinoma and 5 cases of adenoma. Cancer. 1987;59:506–515.

    CAS  PubMed  Google Scholar 

  15. Talamini M, Moesinger R, Pitt H, et al. Adenocarcinoma of the ampulla of Vater. A 28-year experience. Ann Surg. 1997;225:590–600.

    Article  CAS  PubMed  Google Scholar 

  16. Emory RJ, Emory T, Goellner J, Grant C, Nagorney D. Neuroendocrine ampullary tumors: spectrum of disease including the first report of a neuroendocrine carcinoma of non-small cell type. Surgery. 1994;115:762–769.

    PubMed  Google Scholar 

  17. Makhlouf H, Burke A, Sobin L. Carcinoid tumors of the ampulla of vater. Cancer. 1999;85:1241–1249.

    CAS  PubMed  Google Scholar 

  18. Hatzitheokiltos E, Buchler M, Friess H, et al. Carcinoid of the ampulla of Vater: clinical characteristics and morphologic features. Cancer. 1994;73:1580–1588.

    Google Scholar 

  19. Burke A, Sobin L, Federspeil B, Shekitka K, Helwig E. Carcinoid tumors of the duodenum: a clinicopathologic study of 99 cases. Arch Pathol Lab Med. 1990;114:700–704.

    CAS  PubMed  Google Scholar 

  20. Ryan D, Schapiro R, Warshaw A. Villous tumors of the duodenum. Ann Surg. 1986;203:301–306.

    CAS  PubMed  Google Scholar 

  21. Gulliver D, Baker M, Cheng C, Meyers W, Pappas T. Malignant biliary obstruction: efficacy of thin-section dynamic CT in determining resectability. AJR Am J Roentgenol. 1992;159:503–507.

    CAS  PubMed  Google Scholar 

  22. Komorowski R, Beggs B, Geenan J, Venu R. Assessment of ampulla of Vater pathology: an endoscopic approach. Am J Surg Pathol. 1991;15:1188–1196.

    CAS  PubMed  Google Scholar 

  23. Sauvanet A, Chapuis O, Hammel P, et al. Are endoscopic procedures able to predict the benignity of ampullary tumors? Am J Surg. 1997;174:355–358.

    Article  CAS  PubMed  Google Scholar 

  24. Yamaguchi K, Enjoji M, Kitamuran K. Endoscopic biopsy has limited accuracy in diagnosis of ampullary tumors. Gastrointest Endosc. 1990;36:588–592.

    CAS  PubMed  Google Scholar 

  25. Tio T, Mulder C, Eggink W. Endosonography in staging early carcinoma of the ampulla of Vater. Gastroenterology. 1992;102:1392–1395.

    CAS  PubMed  Google Scholar 

  26. Rosch T, Braig C, Gain T, et al. Staging of pancreatic and ampullary carcinoma by endoscopic ultrasonography. Comparison with conventional sonography, computed tomography, and angiography. Gastroenterology. 1992;102:188–199.

    CAS  PubMed  Google Scholar 

  27. Mukai H, Nakajima M, Yasuda K, Mizuno S, Kawai K. Evaluation of endoscopic ultrasonography in the preoperative staging of carcinoma of the ampulla of Vater and common bile duct. Gastrointest Endosc. 1992;38:676–683.

    CAS  PubMed  Google Scholar 

  28. Cannon M, Carpenter S, Elta G, et al. EUS compared with CT, magnetic resonance imaging, and angiography and the influence of biliary stenting on staging accuracy of ampullary neoplasms. Gastrointest Endosc. 1999;50:27–33.

    Article  CAS  PubMed  Google Scholar 

  29. Kubo H, Chijiiwa Y, Akahoshi K, Hamada S, Matsui N, Nawata H. Preoperative staging of ampullary tumours by endoscopic ultrasound. Br J Radiol. 1999;72:443–447.

    CAS  PubMed  Google Scholar 

  30. Menzel J, Hoepffner N, Sulkowski U, et al. Polypoid tumors of the major duodenal papilla: preoperative staging with intraductal US, EUS, and CT-a prospective, histopathologically controlled study. Gastrointest Endosc. 1999;49:349–357.

    Article  CAS  PubMed  Google Scholar 

  31. Binmoeller K, Boaventura S, Ramsperger K, Soehendra N. Endoscopic snare excision of benign adenomas of the papilla of Vater. Gastrointest Endosc. 1993;39:127–131.

    CAS  PubMed  Google Scholar 

  32. Bertoni G, Sassatelli R, Nigrisoli E, Bedogni G. Endoscopic snare papillectomy in patients with familial adenomatous polyposis and ampullary adenoma. Endoscopy. 1997;29:685–688.

    CAS  PubMed  Google Scholar 

  33. Rattner D, Fernandez-del Castillo C, Brugge W, Warshaw A. Defining the criteria for local resection of ampullary neoplasms. Arch Surg. 1996;131:366–371.

    CAS  PubMed  Google Scholar 

  34. Yeo C, Cameron J, Sohn T, et al. Six hundred fifty consecutive pancreaticoduodenectomies in the 1990’s: pathology, complications, and outcomes. Ann Surg. 1997;226:248–257.

    Article  CAS  PubMed  Google Scholar 

  35. Branum G, Pappas T, Meyers W. The management of tumors of the ampulla of Vater by local resection. Ann Surg. 1996;224:621–627.

    Article  CAS  PubMed  Google Scholar 

  36. Allema J, Reinders M, van Gulik T, et al. Results of pancreaticoduodenectomy for ampullary carcinoma and analysis of prognostic factors for survival. Surgery. 1995;117:247–253.

    CAS  PubMed  Google Scholar 

  37. Monson J, Donohue J, McEntee G, et al. Radical resection for carcinoma of the ampulla of Vater. Arch Surg. 1991;126:353–357.

    CAS  PubMed  Google Scholar 

  38. Klein P, Reingruber B, Kastl S, Dworak O, Hohenberger W. Is local excision of pT1-ampullary carcinomas justified? Eur J Surg Oncol. 1996;22:366–371.

    Article  CAS  PubMed  Google Scholar 

  39. Knox R, Kingston R. Carcinoma of the ampulla of Vater. Br J Surg. 1986;73:72–73.

    CAS  PubMed  Google Scholar 

  40. Newman R, Pittam M. Local excision in the treatment of carcinoma of the ampulla of Vater. J R Coll Surg Edinb. 1982;27:154–157.

    CAS  PubMed  Google Scholar 

  41. Robertson J, Imrie C. Local excision of ampullary carcinoma. Acta Chir Scand. 1986;152:537–539.

    CAS  PubMed  Google Scholar 

  42. Tarazi R, Hermann R, Vogt D, et al. Results of surgical treatment of periampullary tumors: a thirtyfive-year experience. Surgery. 1986;100:716–722.

    CAS  PubMed  Google Scholar 

  43. Willet C, Warshaw A, Convery K, Compton C. Patterns of failure after pancreaticoduodenectomy for ampullary carcinoma. Surg Gynecol Obstet. 1993;176:33–38.

    Google Scholar 

Download references

Authors
  1. Bryan Clary
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Theodore N. Pappas
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Douglas Tyler
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Department of Surgical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, 77030, USA

    Douglas B. Evans M.D. (Professor of Surgery) & Peter W. T. Pisters M.D., F.A.C.S. (Associate Professor of Surgery) (Professor of Surgery) &  (Associate Professor of Surgery)

  2. Department of Gastrointestinal Medical Oncology, The University Texas M.D. Anderson Cancer Center, Houston, TX, 77030, USA

    James L. Abbruzzese M.D. (Professor of Medical Oncology, Chairman) (Professor of Medical Oncology, Chairman)

Rights and permissions

Reprints and permissions

Copyright information

© 2002 Springer-Verlag New York, Inc.

About this chapter

Cite this chapter

Clary, B., Pappas, T.N., Tyler, D. (2002). Transduodenal Local Resection for Periampullary Neoplasms. In: Evans, D.B., Pisters, P.W.T., Abbruzzese, J.L. (eds) Pancreatic Cancer. M. D. Anderson Solid Tumor Oncology Series. Springer, New York, NY. https://doi.org/10.1007/0-387-21600-6_15

Download citation

  • DOI: https://doi.org/10.1007/0-387-21600-6_15

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-0-387-95185-0

  • Online ISBN: 978-0-387-21600-3

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation