Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
CDC (Centers for Disease Control). (1999). Achievements in Public Health, 1900–1999: Tobacco Use—United States, 1900–1999. Morb. Mortal. Wkly. Rep. 48: 986–993.
US DHHS (Department of Health and Human Services). (1982). The health consequences of smoking: Cancer. A report of the Surgeon General. Washington, DC.
Doll, R. and Peto, R. (1976). Mortality in relation to smoking: 20 years’ observations on male British doctors. BMJ 2:1525–1536.
Silverstein, P. (1992). Smoking and wound healing. Am. J. Med. 93(Suppl. A1):22S–24S.
Saag, K. G., Cerham, J. R., Kolluri, S., Ohashi, K., Hunninghake, G. W., and Schwartz, D. A. (1997). Cigarette smoking and rheumatoid arthritis severity. Ann. Rheum. Dis. 56:463–469.
Nagai, S., Hoshino, Y., Hayashi, M., and Ito, I. (2000). Smoking-related interstitial lung diseases. Curr. Opin. Pulm. Med. 6:415–419.
Sopori, M. L. (2002). Effects of cigarette smoke on the immune system. Nat. Rev. Immunol. 2:372–377.
Sopori, M. L., Goud, N. S., and Kaplan A. M. (1994). Effects of tobacco smoke on the immune system. In J. H. Dean et al. (eds), Immunotoxicol. Immunopharmacol, Raven Press, NY, pp. 413–433.
Fratiglioni, L. and Wang, H. X. (2000). Smoking and Parkinson’s and Alzheimer’s disease: Review of the epidemiological studies. Behav. Brain. Res 113:117–120.
Manthorpe, R., Benoni, C., Jacobsson, L., Kirtava, Z., Larsson, A., Liedholm, R. et al. (2000) Lower frequency of focal lip sialadenitis (focus score) in smoking patients. Can tobacco diminish the salivary gland involvement as judged by histological examination and anti-SSA/Ro and anti-SSB/La antibodies in Sjogren’s syndrome? Ann. Rheum. Dis. 59:54–60.
Li, Q., Geiselhart, L., Mittler, J. N., Mudzinski, S. P., Lawrence, D. A., and Freed, B. M. (1996). Inhibition of human T lymphoblast proliferation by hydroquinone. Toxicol. Appl. Pharmacol. 139:317–323.
Holian, A. and Li, L. (1998). Acrolein: A respiratory toxin that suppresses pulmonary host defense. Rev. Environ. Health 13:99–108.
Rodriguez, J. W., Kirlen, W. G., Wirsiy, Y. G., Matheravidathu, S., Hodge, T. W., and Urso, P. (1999). Maternal exposure to benzo[a]pyrene alters development of T lymphocytes in offspring. Immunopharmacol. Immunotoxicol. 21:379–396.
Finkelstein, E. L., Nardini, M., and van der Vliet, A. (2001). Inhibition of neutrophil apoptosis by acrolein: A mechanism of tobacco-related lung disease? Am. J. Physiol. Lung Cell. Mol. Physiol. 281:L732–739.
Sopori, M. L., Savage, S. M., Christner, R. F., Geng, Y.-M., and Donaldson, L. A. (1993). Cigarette smoke and the immune response: Mechanism of nicotine-induced immunosuppression. Adv. Biosci. 86:663–672.
Sopori, M. L., Geng, Y., Savage, S. M., Kozak, W., Soszynski, D., Kluger, M. J. et al. (1998). Effect of nicotine on the immune system: Possible regulation of immune responses by central and peripheral mechanisms. Psychoneuroendocrinology 23:189–204.
Geng, Y., Savage, S. M., Johnson, L. J., Seagrave, J., and Sopori, M. L. (1995). Effects of nicotine on the immune response. I. Chronic exposure to nicotine impairs antigen receptor-mediated signal transduction in lymphocytes. Toxicol. Appl. Pharmacol. 135:268–278.
Geng, Y., Savage, S. M., Razani-Boroujerdi, S., and Sopori, M. L. (1996). Effects of nicotine on the immune response: II. Chronic nicotine treatment induces T cell anergy. J. Immunol. 156:2384–2390.
Sopori, M. L. and Kozak, W. (1998). Mechanisms and effects of immunomodulation by cigarette smoke. J. Neuroimmunol. 81:138–146.
Sloan-Lancaster, J. and Allen, P. M. (1996). Altered peptide ligand-induced partial T cell activation: Molecular mechanisms and role in T cell biology. Annu. Rev. Immunol. 14:1–27.
Chan, A., Desai, D., and Weiss, A. (1994). The role of tyrosine kinases and protein tyrosine phosphatases in the antigen receptor signal transduction. Ann. Rev. Immunol. 12:555–592.
Weiss, A. and Littman, D. R. (1994). Signal transduction by lymphocyte antigen receptors. Cell 76:263–274.
Clapham, D. E. (1995). Calcium signaling. Cell 80:258–268.
Kalra, R., Singh, S. P., Savage, S. M., Finch, G. L., and Sopori, M. L. (2000). Effects of cigarette smoke on the immune response: Chronic exposure to cigarette smoke impairs antigen-mediated signaling in T cells and depletes IP3-sensitive Ca2+ stores. J. Pharmacol. Exp. Ther. 293:166–171.
Blalock, J. E. (1994). The immune system, our sixth sense. Immunologist 2:8–15.
Braubar, N. (1995). Direct effects of nicotine on the brain: Evidence for chemical addiction. Arch. Environ. Health 50:263–266.
Seyler, L. E., Jr., Pomerleau, O. F., Fertig, J. B., Hunt, D., and Parker, K. (1986). Pituitary hormone response to cigarette smoking. Pharmacol. Biochem. Behav. 24:159–162.
Singh, S. P., Kalra, R., Puttfarcken, P., Kozak, A., Tesfaigzi, J., and Sopori, M. L. (2000). Acute and chronic nicotine exposures modulate the immune system through different pathways. Toxicol. Appl. Pharmacol. 164:65–72.
Kalra, R., Singh, S. P., Razani-Boroujerdi, S., Langley, R. J., Blackwell, W. B., Henderson, R. F. et al. (2002). Subclinical doses of the nerve gas sarin impair T cell responses through the autonomic nervous system. Toxicol. Appl. Pharmacol. 184:82–87.
Langley, R. J., Kalra, R., Mishra, N. C., and Sopori, M. L. (2004). Central but not the peripheral action of cholinergic compounds suppresses the immune system. J. Neuroimmunol. 148:140–145.
Kohm, A. P. and Sanders, V. M. (2000). Norepinephrine: A messenger from the brain to the immune system. Immunol. Today 21:539–542.
Netscher, D.T. and Clamon, J. (1994). Smoking: Adverse effects on outcome for plastic surgical patients. Plast. Surg. Nurs. 14:205–210.
Krueger, J. K. and Rohrich, R. J. (2001). Clearing the smoke: The scientific rationale for tobacco abstention with plastic surgery. Plast. Reconstr. Surg. 108:1063–1073.
Baron, J. A. (1996). Beneficial effects of nicotine and cigarette smoking: The real, the possible and the spurious. Br. Med. Bull. 52:58–73.
Eskenazi, B. and Warner, M. L. (1997). Epidemiology of endometriosis. Obstet. Gynecol. Clin. North Am. 24:235–258.
Guslandi, M. (1999). Nicotine treatment for ulcerative colitis. Br. J. Clin. Pharmacol. 48:481–484.
Ross, G. W. and Petrovitch, H. (2001). Current evidence for neuroprotective effects of nicotine and caffeine against Parkinson’s disease. Drugs Aging 18:797–806.
Mitsuoka, T., Kaseda, Y., Yamashita, H., Kohriyama, T., Kawakami, H., Nakamura, S. et al. (2002). Effects of nicotine chewing gum on UPDRS score and P300 in early-onset parkinsonism. Hiroshima J. Med. Sci. 51:33–39.
Mills, C. M., Hill, S. A., and Marks, R. (1993). Altered inflammatory responses in smokers. BMJ 307:91
Mills, C. M., Hill, S. A., and Marks, R. (1997). Transdermal nicotine suppresses cutaneous inflammation. Arch. Dermatol. 133:823–825.
Matsunaga, K., Klein, T. W., Friedman, H., and Yamamoto, Y. (2001). Involvement of nicotinic acetylcholine receptors in suppression of antimicrobial activity and cytokine responses of alveolar macrophages to Legionella pneumophila infection by nicotine. J. Immunol. 167:6518–6524.
Myles, M. E., Alack, C., Manino, P. M., Reish, E. R., Higaki, S., Maruyama, K. et al. (2003). Nicotine applied by transdermal patch induced HSV-1 reactivation and ocular shedding in latently infected rabbits. J. Ocul. Pharmacol. Ther. 19: 121–133.
Wang, H., Yu, M., Ochani, M., Amella, C. A., Tanovic, M., Susarla, S. et al. (2003). Nicotinic acetylcholine receptor alpha7 subunit is an essential regulator of inflammation. Nature 421:384–388.
Suzuki, N., Wakisaka, S., Takeba, Y., Mihara, S., and Sakane, T. (1999). Effects of cigarette smoking on Fas/Fas ligand expression of human lymphocytes. Cell. Immunol. 192:48–53.
Clardy, J. (1995) The chemistry of signal transduction. Proc. Natl. Acad. Sci. USA 92:56–61.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2005 Springer Science+Business Media, Inc.
About this chapter
Cite this chapter
Sopori, M.L., Razani-Boroujerdi, S., Singh, S.P. (2005). Immunomodulatory Effects of Cigarette Smoke/Nicotine. In: Friedman, H., Klein, T.W., Bendinelli, M. (eds) Infectious Diseases and Substance Abuse. Infectious Agents and Pathogenesis. Springer, Boston, MA. https://doi.org/10.1007/0-306-48688-1_8
Download citation
DOI: https://doi.org/10.1007/0-306-48688-1_8
Publisher Name: Springer, Boston, MA
Print ISBN: 978-0-306-48687-6
Online ISBN: 978-0-306-48688-3
eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)