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Adolescent Alcohol Drinking and Its Long-Range Consequences

Studies with Animal Models

  • Chapter
Recent Developments in Alcoholism

Part of the book series: Recent Developments in Alcoholism ((RDIA,volume 17))

Abstract

This chapter reviews findings, mainly obtained from the selectively bred alcohol-preferring (P) line of rats, on (a) the development of alcohol drinking during the peri-adolescent period, (b) neurobiological factors that may contribute to adolescent drinking, (c) interventions to prevent alcohol drinking during adolescence, and (d) some long-lasting consequences of adolescent alcohol drinking. The findings indicate that P rats readily initiate alcohol drinking during the early post-weaning, adolescent and peri-adolescent periods of development. The early age-of-onset of alcohol drinking in the P compared to the NP line is associated with (a) higher densities of serotonin-lA (5-HT1IA) receptors in cerebral cortical and hippocampal regions; (b) lower densities of dopamine (DA) D2 receptors in the ventral tegmental area (VTA); (c) higher functional activity in several limbic, cortical and hippocampal regions; and (d) sensitivity to the low-dose stimulating effect of ethanol. Conditioned taste aversion (CTA) training during adolescence produces long-term effects on preventing high alcohol drinking behavior of P rats. Alcohol drinking during peri-adolescence by P rats produces long-lasting effects that increase the acquisition of ethanol self-administration in adulthood, and, in addition, increase craving-like behavior and the potential for alcohol relapse. With suitable animal models, a better understanding of the mechanisms underlying adolescent alcohol drinking and its long-range consequences can be attained.

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References

  • Agabio, R., Carai, M. A. M., Lobina, C., Pani, M., Reali, R., Vacca, G., Gessa, G. L., & Colombo G. (2001). Alcohol stimulates motor activity in selectively bred Sardinian alcohol-preferring (sP), but not in Sardinian alcohol-nonpreferring (sNP), rats. Alcohol, 23, 123–126.

    Article  PubMed  Google Scholar 

  • Anthony, J. C., & Petronis, K. R. (1995). Early onset drug use and risk of later drug problems. Drug and Alcohol Dependence, 40, 9–15.

    Article  PubMed  Google Scholar 

  • Bell, R. L., Rodd-Henricks, Z. A., Kuc, K. A., Lumeng, L., Li, T-K., Murphy, J. M., & McBride, W. J. (2003a). Effects of concurrent access to a single concentration or multiple concentrations of ethanol on the intake of ethanol by male and female periadolescent alcohol-preferring (P) rats. Alcohol, 29, 137–148.

    Article  PubMed  Google Scholar 

  • Bell, R. L., Rodd, Z. A., Hsu, C. C., Lumeng, L., Murphy, J. M., & McBride, W. J. (2003b). Amphetamine-modified acoustic startle responding and prepulse inhibition in adult and adolescent alcohol-preferring and—nonpreferring rats. Pharmacology Biochemistry & Behavior, 75, 163–171.

    Article  Google Scholar 

  • Bell, R. L., Rodd, Z. A., Schultz, J. A., Lumeng, L., Li, T-K., Murphy, J. M., & McBride, W. J. (2003c). Naltrexone disrupts acquisition of ethanol intake in female peri-adolescent alcohol-preferring (P) rats. Alcoholism: Clinical and Experimental Research, 27(suppl), 17A.

    Google Scholar 

  • Chou, S. P., & Pickering, R. P. (1992). Early onset of drinking as a risk factor for lifetime alcohol-related problems. British Journal of Addiction, 87, 1199–1204.

    Article  PubMed  Google Scholar 

  • Cicero, T. J. (1979). A critique of animal analogues of alcoholism. In E. Majchrowicz, EP Noble (Eds.), Biochemistry and Pharmacology of Alcohol (Vol 2 pp 533–560). New York, Plenum Press.

    Google Scholar 

  • Cloninger, C. R. (1987). Neurogenetic adaptive mechanisms in alcoholism. Science, 236, 410–416.

    PubMed  Google Scholar 

  • Cloninger, C. R., Bohman, M., Sigvardsson, S., & Von-Knorring, A. L. (1985). Psychopathology in adopted-out children of alcoholics: The Stockholm adoption study. In Galanter M (Ed): Recent Developments in Alcoholism (Vol 3 pp 37–51). New York, Plenum Press.

    Google Scholar 

  • Domjam, M., & Burkhard, B. (1982). The Principles of Learning and Behavior. Monterey, CA: Brooks/Cole.

    Google Scholar 

  • Fournet, G. P., Estes, R. E., & Martin, G. L. (1990). Drug and alcohol attitudes and usage among elementary and secondary students. Journal of Alcohol and Drug Education, 35, 81–86.

    Google Scholar 

  • Gatto, G. J., Murphy, J. M., Waller, M. B., McBride, W. J., Lumeng, L., & Li, T-K. (1987). Chronic ethanol tolerance through free-choice drinking in the P line of alcohol-preferring rats. Phar macology Biochemistry & Behavior, 28, 111–115.

    Article  Google Scholar 

  • Gatto, G. J., McBride, W. J., Murphy, J. M., Lumeng, L., & Li, T-K.(1994). Ethanol self-infusion into the ventral tegmental area by alcohol-preferring rats. Alcohol, 11, 557–564.

    Article  PubMed  Google Scholar 

  • Haertzen, C. A., Kocher, T., & Miyasato, K. (1983). Reinforcement from the first drug experience can predict late drug habits and/or addiction: Results with coffee, cigarettes, alcohol, barbiturates, minor and major tranquilizers, stimulants, marijuana, hallucinogens, heroin, opiates and cocaine. Drug and Alcohol Dependence, 11, 147–165.

    Article  PubMed  Google Scholar 

  • Hayashi, T., & Tadokoro, S. (1985). Learning retardation and enhanced ethanol preference produced by postnatal pretreatments with ethanol in adult rats. Japanese Journal of Pharmacology, 37, 269–276.

    PubMed  Google Scholar 

  • Ho, A., Chin, A. J., & Dole, V. P. (1989). Early experience and the consumption of alcohol by adult C57BL/6J mice. Alcohol, 6, 511–515.

    Article  PubMed  Google Scholar 

  • Holter, S. M., Engelmann, M., Kirschke, C., Liebsch, G., Landgraf, R., & Spanagel, R. (1998). Long-term ethanol self-administration with repeated ethanol deprivation episodes changes ethanol drinking pattern and increases anxiety-like behavior during ethanol deprivation in rats. Behavioral Pharmacology, 9, 41–48.

    Google Scholar 

  • Johnston, L. D., O'Malley, P. M., & Bachman, J. G. (1991). Drug use Among American High School Seniors, College Students and Young Adults, 1975–1990. Volume 1: High School Seniors. (DHHS Publication No. ADM91-1813). Superintendent of Documents, U.S. Government Printing Office, Washington, DC.

    Google Scholar 

  • Johnston, L. D., O'Malley, P. M., & Bachman, J. G. (1993) Drug use Among American High School Seniors, College Students and Young Adults, 1975–1990. Volume 1:Secondary Students. (DHHS Publication No. ADM93-3597). Superintendent of Documents, U.S. Government Printing Office, Washington, DC.

    Google Scholar 

  • Kelly, P. H., Seviour, P. W., & Iversen, S. D. (1975). Amphetamine and apomorphine responses in the rat following 6-OHDA lesions of the nucleus accumbens septi and corpus striatum. Brain Research, 94, 507–522.

    Article  PubMed  Google Scholar 

  • Krimmer, E. C., & Schechter, M. D. (1991). HAD and LAD rats respond differently to stimulating effect but not discriminative effects of ethanol. Alcohol, 9, 71–74.

    Article  Google Scholar 

  • Lankford, M. E, Roscoe, A. K., Pennington, S. N., & Myers, R. D. (1991). Drinking of high concentrations of ethanol versus palatable fluids in alcohol-preferring (P) rats: Valid animal model of alcoholism. Alcohol, 8, 293–299.

    Article  PubMed  Google Scholar 

  • Litt, M. D., Babor, T. F., Del Boca, F. K., Kadden, R. M., & Cooney, N. L. (1992). Types of alcoholics. II: Application of an empirically derived typology to treatment matching. Archives of General Psychiatry, 49, 609–614.

    PubMed  Google Scholar 

  • Lumeng, L., & Li, T-K. (1986). The development of metabolic tolerance in the alcohol-preferring P rats: Comparison of forced and free-choice drinking of ethanol. Pharmacology Biochemistry & Behavior, 25, 1013–1020.

    Article  Google Scholar 

  • Macintosh, J. J. (1977). Stimulus control: attentional factors. In W.K. Honig, J.E.R. Staddon (Eds.), Handbook on Operant Behavior. Englewood Cliffs NJ: Prentice-Hall.

    Google Scholar 

  • McBride, W. J., & Li, T-K. (1998). Animal models in alcoholism: Neurobiology of high alcohol-drinking behavior in rodents. Critical Reviews in Neurobiology, 12, 339–369.

    PubMed  Google Scholar 

  • McBride, W. J., Chernet, E., Dyr, W., Lumeng, L., & Li, T-K. (1993). Densities of dopamine D2 receptors are reduced in CNS regions of alcohol-preferring P rats. Alcohol, 10, 387–390.

    Article  PubMed  Google Scholar 

  • McBride, W. J., Guan, X-M., Chernet, E., Lumeng, L., & Li, T-K. (1994). Regional serotonin-1A receptors in the CNS of alcohol-preferring and—nonpreferring rats. Pharmacology Biochemistry & Behavior, 49, 7–12.

    Article  Google Scholar 

  • McKinzie, D. L., Eha, R., Murphy, J. M., McBride, W. J., Lumeng, L., & Li, T-K. (1996). Effects of taste aversion training on the acquisition of alcohol drinking in adolescent P and HAD rat lines. Alcoholism: Clinical and Experimental Research, 20, 682–687.

    Article  Google Scholar 

  • McKinzie, D. L., Nowak, K. L., Murphy, J. M., Li, T-K., Lumeng, L., & McBride W. J. (1998a). Development of alcohol drinking behavior in rat lines selectively bred for divergent alcohol preference. Alcoholism: Clinical and Experimental Research, 22, 1584–1590.

    Google Scholar 

  • McKinzie, D. L., Nowak, K. L., Yoger, L., McBride, W. J., Murphy, J. M., Lumeng, L., & Li, T-K. (1998b). The alcohol deprivation effect in the alcohol-preferring P rat under free-drinking and operant access conditions. Alcoholism: Clinical and Experimental Research, 22, 1170–1176.

    Google Scholar 

  • McKinzie, D. L., McBride, W. J., Murphy, J. M., Lumeng, L., & Li, T-K. (2002) Effects of amphetamine on locomotor activity in adult and juvenile alcohol-preferring and—nonpreferring rats. Pharmacology Biochemistry & Behavior, 71, 29–36.

    Article  Google Scholar 

  • Murphy, J. M., McBride, W. J., Lumeng, L., & Li, T-K. (1982). Regional brain levels of monoamines in alcohol-preferring and—nonpreferring lines of rats. Pharmacology Biochemistry & Behavior, 16, 145–149.

    Article  Google Scholar 

  • Murphy, J. M., Gatto, G. J., Waller, M. B., McBride, W. J., Lumeng, L., & Li, T-K. (1986). Effects of schedule access on ethanol intake by the alcohol preferring P line of rats. Alcohol, 3, 331–336.

    Article  PubMed  Google Scholar 

  • Murphy, J. M., McBride, W. J., Lumeng, L., & Li, T-K. (1987). Contents of monoamines in forebrain regions of alcohol-preferring (P) and—nonpreferring (NP) lines of rats. Pharmacology Biochemistry & Behavior, 26, 389–392.

    Article  Google Scholar 

  • Murphy, J. M., Gatto, G. J., McBride, W.J., Lumeng, L., & Li, T-K. (1989). Operant responding for oral ethanol in the alcohol-preferring P and alcohol-nonpreferring NP lines of rats. Alcohol, 6, 127–131.

    Article  PubMed  Google Scholar 

  • Murphy, J. M., Stewart, R. B., Bell, R. L., Badia-Elder, N. E., Carr, L. G., McBride, W. J., Lumeng, L., & Li, T-K. (2002). Phenotypic and genotypic characterization of the Indiana University rat lines selectively bred for high and low alcohol preference. Behavior Genetics, 32, 363–388.

    Article  PubMed  Google Scholar 

  • O'Malley, S. S., Krishnan-Sarin, S., Farren, C., Sinha, R., & Kreek, M. J. (2002). Naltrexone decreases craving and alcohol self-administration in alcohol-dependent subjects and activates the hypothalamo-pituitary-adrenocortical axis. Psychopharmacology, 160, 19–29.

    Article  PubMed  Google Scholar 

  • Paivarinta, P., & Korpi, E. R. (1993). Voluntary ethanol drinking increases locomotor activity in alcohol-preferring AA rats. Pharmacology Biochemistry & Behavior, 44, 127–133.

    Article  Google Scholar 

  • Quine, S., & Stephenson, J. A. (1990). Predicting smoking and drinking intentions and behavior of pre-adolescents: the influence of parents, siblings, and peers. Family Systems Medicine, 8, 191–200.

    Article  Google Scholar 

  • Quintanilla, M. E. (1999). Effect of low doses of ethanol on spontaneous locomotor activity in UChB and UChA rats. Addiction Biology, 4, 443–448.

    Article  Google Scholar 

  • Rodd, Z. A., Bell, R. L., McKinzie, D. L., Webster, A. A., Murphy, J. M., Lumeng, L., Li, T-K., & McBride, W. J. (2004). Low-dose stimulatory effects of ethanol during adolescence in rat lines selectively-bred for high alcohol intake. Alcoholism: Clinical and Experimental Research 28, 535–143.

    Google Scholar 

  • Rodd-Henricks, Z. A., McKinzie, D. L., Shaikh, S. R., Murphy, J. M., McBride, W. J., Lumeng, L., & Li, T-K. (2000). Alcohol deprivation effect is prolonged in the alcohol-preferring (P) rat after repeated deprivations. Alcoholism: Clinical and Experimental Research, 24, 8–16.

    Article  Google Scholar 

  • Rodd-Henricks, Z. A., Bell, R. L., Kuc, K. A., Murphy, J. M., McBride, W. J., Lumeng, L., & Li, T-K. (2001). Effects of concurrent access to multiple ethanol concentrations and repeated deprivations on alcohol intake of alcohol-preferring (P) rats. Alcoholism: Clinical and Experimental Research, 25, 140–1150.

    Article  Google Scholar 

  • Rodd-Henricks, Z. A., Bell, R. L., Kuc, K. A., Murphy, J. M., McBride, W. J., Lumeng, L., & Li, T-K. (2002a). Effects of ethanol exposure on subsequent acquisition and extinction of ethanol self-administration and expression of alcohol-seeking behavior in adult alcohol-preferring (P) rats. I. Periadolescent exposure. Alcoholism: Clinical and Experimental Research, 26, 1632–1641.

    Article  Google Scholar 

  • Rodd-Henricks, Z. A., Bell, R. L., Kuc, K. A., Murphy, J. M., McBride, W. J., Lumeng, L., & Li T-K. (2002b). Effects of ethanol exposure on subsequent acquisition and extinction of ethanol self-administration and expression of alcohol-seeking behavior in adult alcohol-preferring (P) rats. II. Adult exposure. Alcoholism: Clinical and Experimental Research, 26, 1642–1652.

    Article  Google Scholar 

  • Rose, R. J., Dick, D. M., Viken, R. J., & Kaprio, J. (2001). Gene-environment interaction in patterns of adolescent drinking: regional residency moderates longitudinal influences on alcohol use. Alcoholism: Clinical and Experimental Research, 25, 637–643.

    Article  Google Scholar 

  • Sable, H. J. K., Strother, W. N., Rodd, Z. A., Lumeng, L., Li, T-K., & McBride, W. J. (2003). Local cerebral glucose utilization (LCGU) rates in adult alcohol-preferring (P) rats are unaltered by peri-adolescent alcohol drinking. Alcoholism: Clinical and Experimental Research, 27(suppl), 129A.

    Google Scholar 

  • Sahr, A. E., Thielen, R. J., Lumeng, L., Li, T-K., & McBride W. J. (2003). Long-lasting alterations of the mesolimbic dopamine system following periadolescent ethanol drinking by alcohol-preferring (P) rats. Alcoholism: Clinical and Experimental Research (submitted).

    Google Scholar 

  • Salimov, R. M., McBride, W. J., McKinzie, D. L., Lumeng, L., & Li, T-K. (1996). Effects of ethanol consumption by adolescent alcohol-preferring P rats on subsequent behavioral performance in the cross-maze and slip funnel tests. Alcohol, 13, 297–300.

    Article  PubMed  Google Scholar 

  • Sinclair, J. D., & Li, T-K. (1989). Long and short alcohol deprivation: effects on AA and P alcohol-preferring rats. Alcohol, 6, 505–509.

    Article  PubMed  Google Scholar 

  • Slawecki, C. J., & Betancourt, M. (2002). Effects of adolescent ethanol exposure on ethanol consumption in adult rats. Alcohol, 26, 23–30.

    Article  PubMed  Google Scholar 

  • Smith, D. G., Learn, J. E., McBride, W. J., Lumeng, L., Li, T-K., & Murphy, J. M. (2001a). Alcohol-naive alcohol-preferring (P) rats exhibit higher local cerebral glucose utilization than alcohol-nonpreferring (NP) and Wistar rats. Alcoholism: Clinical and Experimental Research, 25, 1309–1316.

    Article  Google Scholar 

  • Smith, D. G., Learn, J. E., McBride, W. J., Lumeng, L., Li, T-K., & Murphy, J. M. (2001b). Long-term effects of alcohol drinking on cerebral glucose utilization in alcohol-preferring rats. Pharmacology Biochemistry & Behavior, 69, 543–553.

    Article  Google Scholar 

  • Sokoloff, L., Reivich, M., Kennedy, C., Des Rosiers, M. H., Patlak, C. S., Pettigrew, K. D., Sakurada, O., & Shinohara, M. (1977). The [14C]deoxyglucose method for the measurement of local cerebral glucose utilization: theory, procedure, and normal values in conscious and anesthetized albino rat. Journal of Neurochemistry, 28, 897–916.

    PubMed  Google Scholar 

  • Spear, L. P. (2000). The adolescent brain and age-related behavioral manifestations. Neuroscience and Biobehavioral Reviews, 24, 417–463.

    Article  PubMed  Google Scholar 

  • Spear, L. P., & Brake, S. C. (1983). Periadolescence: age-dependent behavior and psychopharmacological responsivity in rats. Developmental Psychobiology, 16, 83–109.

    Article  PubMed  Google Scholar 

  • Strother, W. N., Lumeng, L., Li, T-K., & McBride, W. J. (2003a). Regional CNS densities of serotonin-1A and dopamine D2 receptors in periadolescent alcohol-preferring P and alcohol-nonpreferring NP rat pups. Pharmacology Biochemistry & Behavior, 74, 335–342.

    Article  Google Scholar 

  • Strother, W. N., Merrill, C. C., Driscoll, C., Lumeng, L., Li, T-K., & McBride, W. J. (2003b). Effects of acute ethanol on local cerebral glucose utilization (LCGU) in adolescent alcohol-preferring P and alcohol-nonpreferring NP rats. Society for Neuroscience Abstract (submitted).

    Google Scholar 

  • Tolliver, G. A., & Samson, H. H. (1991). The influence of early postweaning ethanol exposure on oral self-administration behavior in the rat. Pharmacology Biochemistry & Behavior, 38, 575–580.

    Article  Google Scholar 

  • Waller, M. B., McBride, W. J., Lumeng, L., & Li, T-K. (1982). Induction of dependence on ethanol by free-choice drinking in alcohol-preferring rats. Pharmacology Biochemistry & Behavior, 16, 501–507.

    Article  Google Scholar 

  • Waller, M. B., McBride, W. J., Gatto, G. J., Lumeng, L., & Li, T-K. (1984). Intragastric self-infusion of ethanol by the P and the NP (alcohol-preferring and—nonpreferring) lines of rats. Science, 225, 78–80.

    PubMed  Google Scholar 

  • Waller, M. B., Murphy, J. M., McBride, W. J., Lumeng, L., & Li, T-K. (1986). Effect of low dose ethanol on spontaneous motor activity in alcohol-preferring and—nonpreferring lines of rats. Pharmacology Biochemistry & Behavior, 24, 617–623.

    Article  Google Scholar 

  • West, C. H. K., Boss-Williams, K. A., & Weiss, J. M. (1999). Motor activation by amphetamine infusion into nucleus accumbens core and shell subregions of rats differentially sensitive to dopaminergic drugs. Behavioral Brain Research, 98, 155–165.

    Article  Google Scholar 

  • Windle, M. (1990). Alcohol use and abuse: some findings from the National Adolescent Student Health Survey. Alcohol Health and Research World, 15,5–10.

    Google Scholar 

  • Wise, R. A., & Bozarth, M. A. (1987). A psychomotor stimulant theory of addiction. Psychological Review, 94, 469–492.

    Article  PubMed  Google Scholar 

  • Witt, E. D. (1994). Mechanisms of alcohol abuse and alcoholism in adolescent: a case for developing animal models. Behavioral Neural Biology, 62, 168–177.

    Google Scholar 

  • Wolffgramm, J., & Heyne, A. (1995) From controlled drug intake to loss of control: the irreversible development of drug addiction in the rat. Behavioral Brain Research, 70, 77–94.

    Article  Google Scholar 

  • Wong, D. T., Reid, L. R., Li, T-K., & Lumeng, L. (1993). Greater abundance of serotonin-lA receptors in some brain areas of alcohol-preferring (P) than nonpreferring (NP) rats. Pharmacology Biochemistry & Behavior, 46, 173–177.

    Article  Google Scholar 

  • Yashimoto, K. (1988). The influence of age upon alcohol drinking behavior. Medical Science Research, 16, 755–756.

    Google Scholar 

  • Zhou, E C., Bledsoe, S., Lumeng, L., & Li, T-K. (1991). Immunostained serotonergic fibers are decreased in selected brain regions of alcohol-preferring rats. Alcohol, 8, 425–431.

    Article  PubMed  Google Scholar 

  • Zhou, F. C., Bledsoe, S., Lumeng, L., & Li, T-K. (1994). Reduced serotonergic immunoreactive fibers in the forebrain of alcohol-preferring rats. Alcoholism: Clinical and Experimental Research, 18, 571–579.

    Article  Google Scholar 

  • Zhou, E C., Zhang, J. K., Lumeng, L., & Li, T-K. (1995). Mesolimbic dopamine system in alcohol-preferring rats. Alcohol, 12, 403–412.

    Article  PubMed  Google Scholar 

  • Zucker, R. A., & Hartford, T. C. (1983). National study of the demography of adolescent drinking practices in 1980. Journal of Studies on Alcohol, 44, 974–985.

    PubMed  Google Scholar 

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Authors and Affiliations

  1. Institute of Psychiatric Research, Indiana University School of Medicine, Indianapolis, Indiana, 46202-4887

    William J. McBride, Richard L. Bell, Zachary A. Rodd, Wendy N. Strother & James M. Murphy

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  1. William J. McBride
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  2. Richard L. Bell
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  4. Wendy N. Strother
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  1. New York University School of Medicine, New York, New York

    Marc Galanter

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McBride, W.J., Bell, R.L., Rodd, Z.A., Strother, W.N., Murphy, J.M. (2005). Adolescent Alcohol Drinking and Its Long-Range Consequences. In: Galanter, M., Lowman, C., Boyd, G.M., Faden, V.B., Witt, E., Lagressa, D. (eds) Recent Developments in Alcoholism. Recent Developments in Alcoholism, vol 17. Springer, Boston, MA. https://doi.org/10.1007/0-306-48626-1_6

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