Mechanisms of Yersinia enterocolitica Evasion of the Host Innate Immune Response by V Antigen
Our data demonstrate a new ligand specificity of TLR2, since LcrV is the first known secreted and non-lipidatedvirulence-associated protein of a Gram-negative bacterium utilizing TLR2 for cell activation. We conclude that yersiniae might exploit host innatepattern recognition molecules and defense mechanisms to evade the host immune response.
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