Advertisement

Polyclonal B-Cell Activation in Mice Infected by Intragastric Route with Yersinia enterocolitica O:8

  • Beatriz M. M. Medeiros
  • Orivaldo P. Ramos
  • Eloisa E.E. Silva
  • Deise P. Falcão
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 529)

Conclusion

The infection of mice with virulent and avirulent strains of Y. enterocolitica O: 8 resulted in polyclonal activation of the repertory of spleen and Peyer’s patches B lymphocytes, including some autoreactives clones.

Keywords

Yersinia Enterocolitica Avirulent Strain Immunoglobulin Isotype Polyclonal Activation Autoreactives Clone 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Czerkinsky, C. C., Nilsson, L. A., Nygren, H., Ouchterlony, O., and Tarkowsi, A., 1983, A solid-phase enzyme-linked immunospot (ELISPOT) assay for enumeration of specific antibody-secreting cells. J. Immunol. Methods, 65:109–121.CrossRefPubMedGoogle Scholar
  2. Heinicke, E., Kumar, U., and Munoz, D. G., 1992, Quantitative dot-blot assay for proteins using enhanced chemiluminescence. J. Immunol. Methods., 152:227–236.CrossRefPubMedGoogle Scholar
  3. Medeiros, B.M.M., Mendes-Giannini, M. J. S. and Falcão, D. P., 1991, Immunoglobulin isotypes produced by mice experimentally infected with Yersinia sp. Contrib Microbiol Immunol, 21:117–122Google Scholar

Copyright information

© Kluwer Academic Publishers 2004

Authors and Affiliations

  • Beatriz M. M. Medeiros
    • 1
  • Orivaldo P. Ramos
    • 1
  • Eloisa E.E. Silva
    • 1
  • Deise P. Falcão
    • 1
  1. 1.Department of Biological Sciences, School of Pharmaceutical SciencesUNESPAraraquara, SPBrazil

Personalised recommendations