Cytokine Production of Peripheral Blood Mononuclear Cells Stimulated with Streptococcus Sanguis Antigen in Patients with Behçet’s Disease
After 72 hrs, the production of IFN-γ was significantly increased in patients with active BD as compared with controls or patients with inactive disease. However, there was no significant increase of IL-4. Taking time course into consideration, IFN-γ production increased with time starting 6 hrs after the incubation with the antigen and the reaction was also dose-dependent with respect to the amount of antigen.
KeywordsCell Antigen Inactive Disease Inactive Stage Cytokine Production Profile Peripheral Blood Mononuclear Cell Stimulate
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