Conclusions
Recurrent HNSCC remains a complex and frustrating disease. Given the experience of the past decade, expectations that improvements in outcome with traditional cytotoxins will ensue have been dampened. Molecularly targeted agents are under active investigation and hold more promise for improving the plight of our patients. These agents will likely have the greatest impact when used in combination with chemotherapy. It seems unlikely, however, that we will begin to cure these patients who currently have a life expectancy of 6–9 months. Palliation will remain the intent of therapy in the recurrent setting and for this reason it is paramount that we focus on these effects in our research.
Keywords
- Epidermal Growth Factor Receptor
- Squamous Cell Carcinoma
- Clin Oncol
- Neck Cancer
- Neck Squamous Cell Carcinoma
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Kim, E.S., Glisson, B.S. (2004). Treatment of Metastatic Head and Neck Cancer: Chemotherapy and Novel Agents. In: Bruce, B., Gregory, M. (eds) Head and Neck Cancer. Cancer Treatment and Research, vol 114. Springer, Boston, MA. https://doi.org/10.1007/0-306-48060-3_12
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