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Postexposure Prophylaxis for Occupational Exposure and Sexual Assault

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AIDS in Africa

Conclusion

Randomized studies of PEP cannot be carried out for ethical and practical reasons. There are, however, many arguments supporting the use of anti-HIV PEP following ABE or sexual assault. States and health systems in resource-poor countries face the challenge of guaranteeing exposed HCWs and rape victims full-time and free-of-charge access to a physician capable of conducting a risk assessment, PEP drugs, and technical facilities for biologic assessment and serologic monitoring. Nonetheless, the use of HIV PEP in African countries must be supported and increased. Such efforts however, must also include the support and assurance of exposure prevention practices and a reduction in ABE incidence in health care settings. Likewise, efforts to reduce sexual violence worldwide must be stepped up.

While the number of occupationally infected HCWs is not in itself a public health crisis in comparison with the growing number of infections in the general population in Africa, ABE is a public health issue, as is the fear of occupational infection faced by ill-paid, ill-protected, and overworked HCWs in resource-poor countries. Providing prevention training, support, and free access to PEP is an ethical and fair measure that will help support HCWs in Africa in their continuing effort to provide quality care to an increasing number of HIV-infected patients.

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Authors and Affiliations

  1. Hôpital Bichat-Claude Bernard, Paris, France

    Elisabeth Bouvet

  2. Institut de Veille Sanitaire, Saint-Maurice, France

    Anne Laporte

  3. World Health Organization, Genera, Switzerland

    Arnaud Tarantola

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  1. Elisabeth Bouvet
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Editors and Affiliations

  1. Harvard AIDS Institute Mary Woodard Lasker Professor of Health Sciences Harvard University, Boston, Massachusetts, USA

    Max Essex DVM, PhD (Chairman) & Richard G. Marlink MD (Senior Research and Executive Director) (Chairman) &  (Senior Research and Executive Director)

  2. Laboratory of Bacteriology and Virology CHU Le Dantec, Université Cheikh Anta Diop, Dakar, Senegal

    Souleymane Mboup PharmD, PhD (Professor of Microbiology) (Professor of Microbiology)

  3. Department of Immunology and Infectious Diseases and the Harvard AIDS Institute, Harvard School of Public Health, Boston, Massachusetts, USA

    Phyllis J. Kanki DVM, DSc (Professor of Immunology and Infectious Diseases) & Molly Holme (Professor of Immunology and Infectious Diseases) & 

  4. Department of Nursing Education University of Botswana, Gaborone, Botswana

    Sheila D. Tlou PhD (Associate Professor) (Associate Professor)

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Bouvet, E., Laporte, A., Tarantola, A. (2002). Postexposure Prophylaxis for Occupational Exposure and Sexual Assault. In: Essex, M., Mboup, S., Kanki, P.J., Marlink, R.G., Tlou, S.D., Holme, M. (eds) AIDS in Africa. Springer, Boston, MA. https://doi.org/10.1007/0-306-47817-X_37

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