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Clinical Diagnosis of AIDS and HIV-Related Diseases

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AIDS in Africa

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Conclusion

This chapter reviewed the development, refinement, and expansion of AIDS case definitions. Their limitations have been discussed, and the need to develop more accurate, regularly updated second-generation surveillance case definitions was emphasized. While many clinicians might apply these surveillance case definitions and HIV/AIDS clinical staging classifications interchangeably, it is important to make a clear distinction between surveillance tools and clinical staging systems. The diagnostic approach to any patient follows a distinctly different clinical algorithm to the principles of epidemiologic surveillance.

A cross-section of HIV-related disorders was selected to highlight the magnitude of diagnostic problems facing most clinicians working in sub-Saharan Africa. The list is by no means exhaustive. Given the meager resources in many African countries, our zeal to clinch difficult diagnoses in HIVinfected patients must be carefully balanced by efforts to give patients the best palliative care possible.

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Authors and Affiliations

  1. Department of Medicine, Princess Marina Hospital, Gaborone, Botswana

    Churchill Lukwiya Onen

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Editors and Affiliations

  1. Harvard AIDS Institute Mary Woodard Lasker Professor of Health Sciences Harvard University, Boston, Massachusetts, USA

    Max Essex DVM, PhD (Chairman) & Richard G. Marlink MD (Senior Research and Executive Director) (Chairman) &  (Senior Research and Executive Director)

  2. Laboratory of Bacteriology and Virology CHU Le Dantec, Université Cheikh Anta Diop, Dakar, Senegal

    Souleymane Mboup PharmD, PhD (Professor of Microbiology) (Professor of Microbiology)

  3. Department of Immunology and Infectious Diseases and the Harvard AIDS Institute, Harvard School of Public Health, Boston, Massachusetts, USA

    Phyllis J. Kanki DVM, DSc (Professor of Immunology and Infectious Diseases) & Molly Holme (Professor of Immunology and Infectious Diseases) & 

  4. Department of Nursing Education University of Botswana, Gaborone, Botswana

    Sheila D. Tlou PhD (Associate Professor) (Associate Professor)

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Onen, C.L. (2002). Clinical Diagnosis of AIDS and HIV-Related Diseases. In: Essex, M., Mboup, S., Kanki, P.J., Marlink, R.G., Tlou, S.D., Holme, M. (eds) AIDS in Africa. Springer, Boston, MA. https://doi.org/10.1007/0-306-47817-X_18

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  • DOI: https://doi.org/10.1007/0-306-47817-X_18

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