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The Role of Nutritional Support in Sepsis

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The Sepsis Text

Conclusion

The critically ill patient with sepsis experiences a unique pathophysiologic state that promotes deterioration of organ function and systemic immunity. Beyond its effect on nutritional status, providing nutritional support by the enteral route may modify the course of sepsis through maintenance of gut structure and function, thereby reducing the inflammatory response to sepsis, and improving clinical outcomes. Parenteral nutrition seems to have little role and may even worsen outcomes in sepsis. While use of immune-enhancing nutrients may be helpful in a variety of patient groups who are non-septic, evidence for possible deleterious effects may prevent their use in patients who have pre-existing infection. Careful selection and close monitoring should maximize efficacy and benefit from the nutritional support regimen in this complex patient population.

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Authors
  1. Daren K. Heyland
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  2. James K. Lukan
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  3. Stephen A. McClave
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Editor information

Editors and Affiliations

  1. Department of Intensive Care, Erasme University Hospital, Brussels, Belgium

    Jean-Louis Vincent M.D.

  2. Service de Réanimation Polyvalente, Hôpital Saint-Joseph, Paris, France

    Jean Carlet M.D.

  3. Division of Infectious Diseases, The Memorial Hospital of Rhode Island, Pawtucket, RI

    Steven M. Opal M.D.

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© 2002 Kluwer Academic Publishers

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Heyland, D.K., Lukan, J.K., McClave, S.A. (2002). The Role of Nutritional Support in Sepsis. In: Vincent, JL., Carlet, J., Opal, S.M. (eds) The Sepsis Text. Springer, Boston, MA. https://doi.org/10.1007/0-306-47664-9_27

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  • DOI: https://doi.org/10.1007/0-306-47664-9_27

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-0-7923-7620-0

  • Online ISBN: 978-0-306-47664-8

  • eBook Packages: Springer Book Archive

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