Skip to main content

The Predominant Varicella-zoster Virus gE and gI Glycoprotein Complex

  • Chapter
Structure-Function Relationships of Human Pathogenic Viruses

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Abramson, A.W., 1944, Varicella and herpes zoster: an experiment. Br. Med. J. 1:812–13

    Google Scholar 

  • Alconada, A., Bauer, U., and Hoflack, B., 1996, A tyrosine-based motif and a casein kinase II phosphorylation site regulate the intracellular trafficking of the varicella-zoster virus glycoprotein I, a protein localized in the trans-Golgi network. Embo J. 15:6096–6110

    PubMed  CAS  Google Scholar 

  • Arvin, A.M., Kinney-Thomas, E., Shriver, K., Grose, C., Koropchak, C.M., Scranton, E., Wittek, A.E., and Diaz, P.S., 1986, Immunity to varicella-zoster viral glycoproteins, gpI (gp90/58) and gpIII (gp118), and to nonglycosylated protein. J. Immunol. 137:1346–1351

    PubMed  CAS  Google Scholar 

  • Bergen, R.E., Sharp, M., Sanchez, A., Judd, A.K., and Arvin, A.M., 1991, Human T cells recognize multiple epitopes on an immediate early/tegument protein (IE62) and glycoprotein I of varicella zoster virus. Viral Immunol. 4:151–166

    Article  PubMed  CAS  Google Scholar 

  • Bosc, D.G., Slominski, E., Sichler, C., and Litchfield, D.W., 1995, Phosphorylation of casein kinase II by p34 cdc2. J. Biol. Chem. 270:25872–25878

    PubMed  CAS  Google Scholar 

  • Bremnes, B., Madsen, T., Gedde-Dahl, M., and Bakke, O., 1994, An LI and ML motif in the cytoplasmic tail of the MHC-associated invariant chain mediates rapid internalization. J. Cell Scienc. 107:2021–2032

    CAS  Google Scholar 

  • Brookes, A.J., 1999, The essence of SNPs. Gene. 234:177–186

    Article  PubMed  CAS  Google Scholar 

  • Cohen, J. I., and Nguyen, H., 1997, Varicella-zoster virus glycoprotein I is essential for growth of virus in Vero cells. J. Virol. 71:6913–6920

    PubMed  CAS  Google Scholar 

  • Collawn, J.F., Stangel, M., Kuhn, L.A., Esekogwu, V., Jing, S., Trowbridge, I.S., and Trainer, J.A., 1990, Transferrin receptor internalization sequence YXRF implicates a tight turn as the structural recognition motif for endocytosis. Cell 63:1061–1072

    Article  PubMed  CAS  Google Scholar 

  • Collins, F.S., Guyer, M.S., and Chakravarti, A., 1997, Variations on a theme: Cataloguing human DNA sequence variation. Science 278:1580–1581

    PubMed  CAS  Google Scholar 

  • Davison, A.J., and Scott, J.E., 1986, The complete DNA sequence of varicella-zoster virus. J. Gen. Virol. 67:1759–1816

    PubMed  CAS  Google Scholar 

  • Dingwell, K.S., Brunetti, C.R., Hendriks, R.L., Tang, Q., Tang, M., Rainbow, A.J., and Johnson, D.C., 1994, Herpes simplex virus glycoproteins E and I facilitate cell-to-cell spread in vivo and across junctions of cultured cells. J. Virol. 68:834–845

    PubMed  CAS  Google Scholar 

  • Duus, K., and Grose, C., 1996, Multiple regulatory effects of varicella-zoster virus gL on trafficking patterns and fusogenic properties of VZV and gH. J. Virol. 70:8961–8971

    PubMed  CAS  Google Scholar 

  • Edson, C.M., 1993, Tyrosine sulfation of varicella-zoster virus envelope glycoprotein gpI. Virology 197:159–165

    Article  PubMed  CAS  Google Scholar 

  • Edson, C.M., Hosier, B.A., Poodry, C.A., Schooley, R.T., Waters, D.J., and Thorley-Lawson, D.A., 1985, Varicella-zoster virus envelope glycoproteins: biochemical characterization and identification in clinical material. Virology 145:62–71

    Article  PubMed  CAS  Google Scholar 

  • Faga, B., Maury, W., Bruckner, D.A., and Grose, C., 2001, Identification and mapping of single nucleotide polymorphisms in the varicella-zoster virus genome. Virology 280:1–6

    Article  PubMed  CAS  Google Scholar 

  • Gershon, A., Cosio, L., and Brunell, P.A., 1973, Observations on the growth of varicella-zoster virus in human diploid cells. J. Gen. Virol. 18:21–31

    PubMed  CAS  Google Scholar 

  • Grose, C., 1980, The synthesis of glycoproteins in human melanoma cells infected with varicella-zoster virus. Virology 101:1–9

    Article  PubMed  CAS  Google Scholar 

  • Grose, C., 1990, Glycoproteins encoded by varicella-zoster virus: biosynthesis, phosphorylation, and intracellular trafficking. Ann. Rev. Microbiol. 44:59–80

    Article  CAS  Google Scholar 

  • Grose, C., 1991, Glycoproteins of varicella-zoster virus and their herpes simplex virus homologs. Rev. Infect. Dis. 13:S960–963

    Google Scholar 

  • Grose, C., 1999, Varicella-zoster virus: Less immutable than once thought. Pediatrics 103:1027–1028

    Article  PubMed  CAS  Google Scholar 

  • Grose, C., Edmond, B.J., and Friedrichs, W.E., 1981, Immunogenic glycoproteins of laboratory and vaccine strains of varicella-zoster virus. Infect. Immun. 31:1044–1053

    PubMed  CAS  Google Scholar 

  • Grose, C., and Friedrichs, W.E., 1982, Immunoprecipitable polypeptides specified by varicella-zoster virus. Virology 118:86–95

    Article  PubMed  CAS  Google Scholar 

  • Grose, C., Friedrichs, W.E., and Smith, G.C., 1983, Purification and molecular anatomy of the varicella-zoster virion. Biken J. 26:1–15

    PubMed  CAS  Google Scholar 

  • Grose, C., Jackson, W., and Traugh, J.A., 1989, Phosphorylation of varicella-zoster virus glycoprotein gpI by mammalian casein kinase IIand casien kinase I. J. Virol. 63:3912–3918

    PubMed  CAS  Google Scholar 

  • Harper, D.R., and Kangro, H.O., 1990, Lipoproteins of varicella-zoster virus. J. Gen. Virol. 71:459–463

    Article  PubMed  CAS  Google Scholar 

  • Harson, R., and Grose, C., 1995, Egress of varicella-zoster virus from the melanoma cell: a tropsim for the melanocyte. J. Virol. 69:4994–5010

    PubMed  CAS  Google Scholar 

  • Hatfield, C., Duus, K.M., Jones, D.J., and Grose, C., 1997, Epitope mapping and tagging by recombination PCR mutagenesis. BioTechniques 22:332–337

    PubMed  CAS  Google Scholar 

  • Hope-Simpson, R.E., 1965, The nature of herpes zoster: a long-term study and new hypothesis. Proc. Roy. Soc. Med. (Lond.). 58:9–20

    CAS  Google Scholar 

  • Ito, M., Ihara, T., Grose, C., and Starr, S., 1985, Human leukocytes kill varicella-zoster virus infected fibroblasts in the presence of murine monoclonal antibodies to virus-specific glycoproteins. J. Virol. 54:98–102

    PubMed  CAS  Google Scholar 

  • Jones, F., and Grose, C., 1988, Role of cytoplasmic vaeuoles in varicella-zoster virus glycoprotein trafficking and virion envelopment. J. Virol. 62:2701–2711

    PubMed  CAS  Google Scholar 

  • Kimura, H., Straus, S.E., and Williams, R.K., 1997, Varicella-zoster virus glycoproteins E and I expressed in insect cells form a heterodimer that requires the N-terminal domain of glycoprotein I. Virology 233:382–391

    Article  PubMed  CAS  Google Scholar 

  • Kishimoto, A., Brown, M.S., Slaughter, C.A., and Goldstein, J.L., 1987, Phosphorylation of serine 833 in cytoplasmic domain of low intensity lipoprotein receptor by a high molecular weight enzyme resembling casein kinase II. J. Biol. Chem. 262:1344–1351

    PubMed  CAS  Google Scholar 

  • Letourneur, F., and Klausner, R.D., 1992, A novel di-leucine motif and a tyrosine-based motif independently mediate lysosomal targeting and endocytosis of CD3 chains. Cell 69:1143–1157

    Article  PubMed  CAS  Google Scholar 

  • Litchfield, D.W., Bosc, D.G., and Slominski, E., 1995, The protein kinase from mitotic human cells that phosphorylates Ser-209 on the casein kinase II β-subunits is p34 cdc2. Biochim. Biophys. Acta 1269:69–78

    PubMed  Google Scholar 

  • Ltiwin, V., and Grose, C., 1992, Herpesviral Fc receptors and their relationship to the human Fc receptors. Immunologic Research 11:226–38

    Google Scholar 

  • Litwin, V., Jackson, W., and Grose, C., 1992, Receptor properties of two varicella-zoster virus glycoproteins gpI and gpIV homologous to herpes simplesvirus gE and gI. J. Virol. 66:3643–51

    PubMed  CAS  Google Scholar 

  • Litwin, V., Sandor, M., and Grose, C., 1990, Cell surface expression of the varicella-zoster virus glycoproteins and Fc receptor. Virology 178:263–272

    Article  PubMed  CAS  Google Scholar 

  • Mallory, S., Sommer, M., and Arvin, A.M., 1997, Mutational analysis of the role of glycoprotein I in varicella-zoster virus replication and its effects on glycoprotein E conformation and trafficking. J. Virol. 71:8279–8288

    PubMed  CAS  Google Scholar 

  • Montalvo, E.A., and Grose, C., 1986, Varicella zoster virus glycoprotein gpI is selectively phosphorylated by a virus-induced protein kinase. Proc. Nat. Acad. Sci. USA. 83:8967–8971

    PubMed  CAS  Google Scholar 

  • Montalvo, E.A., Parmley, R.T., and Grose, C., 1985, Structural analysis of the varicella-zoster virus gp98-gp62 complex: Posttranslational addition of N-linked and O-linked oligosaccharide moieties. J. Virol. 53:761–770

    PubMed  CAS  Google Scholar 

  • Namazue, J., Kato, T., Okuno, T., Shiraki, K,. and Yamanishi, K., 1989, Evidence for attachment of fatty acid to varicella-zoster virus glycoproteins and effect of cerulenin on the maturation of varicella-zoster virus glycoproteins. Intervirology. 30:268–277

    PubMed  CAS  Google Scholar 

  • Ng, T., and Grose, C., 1992, Serine protein kinase associated with varicella-zoster virus ORF 47, Virology 191:9–18

    Article  PubMed  CAS  Google Scholar 

  • Ng, T., Keenan, L., Kinchington, P.R., and Grose, C., 1994, Phosphorylation of varicellazoster virus open reading frame (ORF) 62 regulatory product by viral ORF 47 associated protein kinase. J. Virol. 68:1350–1359

    PubMed  CAS  Google Scholar 

  • Olson, J., Bishop, G., and Grose, C., 1997, Varicella-zoster virus Fc receptor gE glycoprotein: Serine/threonine and tyrosine phosphorylation of monomeric and dimeric forms. J. Virol. 71:110–119

    PubMed  CAS  Google Scholar 

  • Olson, J.K., and Grose, C., 1997, Endocytosis and recycling of varicella-zoster virus Fc receptor glycoprotein gE: internalization mediated by YXXL motif in the cytoplasmic tail. J. Virol. 71:4042–4054

    PubMed  CAS  Google Scholar 

  • Olson, J.K., and Grose, C., 1998, Complex formation facilitates endocytosis of the varicella-zoster virus gE:gI Fc receptor. J Virol. 72:1542–1551

    PubMed  CAS  Google Scholar 

  • Santos, R.A., Hatfield, C.C., Cole, N.L., Padilla, J.A., Moffat, J.F., Arvin, A.M., Ruyechan, W.T., Hay, J., and Grose, C., 2000, Varicella-zoster virus gE escape mutant VZV-MSP exhibits an accelerated cell-to-cell spread phenotype in both infected cell cultures and SCID-hu mice. Virology 275:306–317

    Article  PubMed  CAS  Google Scholar 

  • Santos, R.A., Padilla, J.A., Hatfield, C.C., and Grose, C., 1998, Antigenic variation of caricella zoster virus Fc receptor gE: loss of a major B cell epitope in the ectodomain. Virology 249:21–31

    Article  PubMed  CAS  Google Scholar 

  • Takahashi, M., Okuno, Y., Otsuka, T., Osame, J., Takamizawa, A., Sasada, T., and Kubo, T., 1975, Development of a live attenuated varicella vaccine. Biken J. 18:25–33

    PubMed  CAS  Google Scholar 

  • Trowbridge, I.S., Collawn, J.F., and Hopkins, C.R., 1993, Signal-dependent trafficking in the endocytic pathway. Ann. Rev. Cell Biol. 9:129–161

    PubMed  CAS  Google Scholar 

  • Tugizov, S., Maidji, E., Xiao, J., Zheng, Z., and Pereira, L., 1998, Human cytomegalovirus glycoprotein B contains autonomous determinants for vectorial targeting to apical membranes of polarized epithelial cells. J. Virol. 72:7374–7386

    PubMed  CAS  Google Scholar 

  • Vafai, A., Wroblewska, Z., Mahalingham, R, Cabirac, G., Wellish, M., Cisco, M., Gilden D. Recognition of similar epitopes on varicella-zoster virus gpI and gpIV by monoclonal antibodies. J. Virol. 62: 2544–2551.

    Google Scholar 

  • Wang, D.G., Fan, J.B., Siao, C.J., Berno, A., Young, P., Sapolsky, R., Ghandour, G., Perkins, N., Winchester, E., Spencer, J., Kruglyak, L., Stein, L., Hsie, L., Topaloglou, T., Hubbel, E., Robinson, E., Mittmann, M., Morrris, M.S, Shen, N., Kilburn, D., Rioux, J., Nusbaum, C., Rozen, S., Hudson, T.J., Liptshutz, R., Chee, M., and Lander, E.S., 1998, Large-scale identification, mapping, and genotyping of single-nucleotide polymorphisms in the human genome. Science 280:1077–1082

    PubMed  CAS  Google Scholar 

  • Weigle, K.A., and Grose, C., 1983, Common expression of varicella-zoster virus glycoprotein antigens in vitro and in chickenpox and zoster vesicles. J. Infect. Dis. 148:630–638

    PubMed  CAS  Google Scholar 

  • Weigle, K.A., and Grose, C., 1984, Molecular dissection of the humoral immune response to individual varicella-zoster virus proteins during chickenpox, quiescence, reexposure, and reactivation. J. Infect. Dis. 149:741–749

    PubMed  CAS  Google Scholar 

  • Weller, T.H., 1953, Serial propagation in vitro of agents producing inclusion bodies derived from varicella and herpes zoster. Proc. Soc. Exp. Biol. Med. 83:340–346

    PubMed  CAS  Google Scholar 

  • Yao, Z., and Grose, C., 1994, Unusual phosphorylation sequence on the gpIV (gI) component of the varicella-zoster virus (VZV) gpI-gpIVglycoprotein complex (VZV gE-gI complex). J. Virol 68:4202–4211

    Google Scholar 

  • Yao, Z., Jackson, W., Forghani, B., and Grose, C., 1993, Varicella-zoster virus glycoprotein gpI/gpIV receptor: Expression, complex formation, and antigenicity within the vaccinia virus-T7 RNA polymerase transfection system. J. Virol. 67:305–314

    PubMed  CAS  Google Scholar 

  • Yao, Z., Jackson, W., and Grose, C., 1993, Identification of the phosphorylation sequence in the cytoplasmic tail of the varicella-zoster virus Fc receptor glycoprotein gpI. J. Virol. 67:4464–4473

    PubMed  CAS  Google Scholar 

  • Yao, Z., Jones, D.H., and Grose, C., 1992, Site-directed mutagenesis of herpesvirus glycoprotein phosphorylation sites by recombination polymerase chain reaction. PCR Methods Appl. 1:205–207

    PubMed  CAS  Google Scholar 

  • Ye, M., Duus, K.M., Peng, J., Price, D.H., and Grose, C., 1999, Varicella-zoster virus Fc receptor component gI is phosphorylated in its endodomain by a cyclin dependent kinase. J. Virol. 73:1320–1330

    PubMed  CAS  Google Scholar 

  • Zhu, Z., Gershon, M.D., Hao, Y., Ambron, R.T., Gabel, C.A., and Gershon, A.A., 1995. Envelopment of varicella-zoster virus: targeting of viral glycoproteins to the trans-Golgi network. J. Virol. 69:7951–7959

    PubMed  CAS  Google Scholar 

  • Zhu, Z., Hao, Y., Gershon, M.D., Ambron, R.T., and Gershon, A.A., 1996, Targeting of glycoprotein I (gE) of varicella-zoster virus to the trans-Golgi network by an AYRV sequence and an acidic amino-acid rich patch in the cytosolic domain of the molecule. J. Virol. 70:6563–6575

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2002 Kluwer Academic Publishers

About this chapter

Cite this chapter

Grose, C. (2002). The Predominant Varicella-zoster Virus gE and gI Glycoprotein Complex. In: Holzenburg, A., Bogner, E. (eds) Structure-Function Relationships of Human Pathogenic Viruses. Springer, Boston, MA. https://doi.org/10.1007/0-306-47650-9_8

Download citation

  • DOI: https://doi.org/10.1007/0-306-47650-9_8

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-0-306-46768-4

  • Online ISBN: 978-0-306-47650-1

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics