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Role of Envelope Proteins in Measles Virus Assembly

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Structure-Function Relationships of Human Pathogenic Viruses

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References

  • Alkathib, G., Roder, J., Richardson, C. D., Briedis, D., Weinberg, R., Smith, D., Taylor, J., Paoletti, E., and Shen, S.-H., 1994a, Characterization of a cleavage mutant of measles virus fusion protein defective in syncytium formation. J. Virol. 68:6770–6774.

    Google Scholar 

  • Alkhatib, G., and Briedis, D., 1986, The predicted primary structure of measles virus hemagglutinin. Virology 150:479–490.

    Article  PubMed  CAS  Google Scholar 

  • Alkhatib, G., Shen, S. H., Briedis, D., Richardson, C., Massie, B., Weinberg, R., Smith. D., Taylor, J., Paoletti, E., and Roder, J., 1994b, Functional analysis of N-linked glycosylation mutants of the measles virus fusion protein synthesized by recombinant vaccinia virus vectors. J. Virol. 68:1522–1531.

    PubMed  CAS  Google Scholar 

  • Baczko, K., Billeter, M. A., and ter Meulen, V., 1983, Purification and molecular weight determination of measles virus genomic RNA. J. Gen. Virol. 64:1409–1413.

    PubMed  CAS  Google Scholar 

  • Barry, D. W., Sullivan, J. L., Lucas, S. L., Dunlap, R. C., and Albrecht, P., 1976, Acute and chronic infection of human lymphoblastoid cell lines with measles virus. J. Immunol. 116:89–98.

    PubMed  CAS  Google Scholar 

  • Bartz, R., Brinckmann, U., Dunster, L. M., Rima, B., ter Meulen, V., and Schneider-Schaulies, J., 1996, Mapping amino acids of the measles virus hemagglutinin responsible for receptor (CD46) downregulation. Virology 224:334–337.

    Article  PubMed  CAS  Google Scholar 

  • Bartz, R., Firsching, R., Rima, B., ter Meulen, V., and Schneider-Schaulies, J., 1998, Differential receptor usage by measles virus strains. J. Gen. Virol. 79:1015–25.

    PubMed  CAS  Google Scholar 

  • Bellini, W. J., Englund, G., Richardson, C. D., Rozenblatt, S., and Lazzarini, R. A., 1986, Matrix genes of measles virus and canine distemper virus: cloning, nucleotide sequences, and deduced amino acid sequences. J. Virol. 58:406–416.

    Google Scholar 

  • Bergmann, J. E., and Fusco, P. J., 1988, The M protein of Vesicular stomatitis virus associates specifically with the basolateral membrane of polarized epithelial cells independently of the G protein. J. Cell Biol. 107, 1707–1715.

    Article  PubMed  CAS  Google Scholar 

  • Blau, D. M., and Compans, R. W., 1995, Entry and release of measles virus are polarized in epithelial cells. Virology 210:91–99.

    Article  PubMed  CAS  Google Scholar 

  • Bohn, W., Rutter, G., Hohenberg, H., Mannweiler, K., and Nobis, P., 1986, Involvement of actin filaments in budding of measles virus: studies on cytoskeletons of infected cells. Virology 149:91–106.

    Article  PubMed  CAS  Google Scholar 

  • Breckford, A. P., Kaschula, R. O. C., and Stephen, C., 1985, Factors associated with fatal cases of measles: a retrospective autopsy study. S. Afr. Med. J. 68:858–863.

    Google Scholar 

  • Buchholz, C., Koller, D. Devaux, P., Mumenthaler, C., Schneider-Schaulies, J., Braun, W., Gerlier, D., and Cattaneo, R., 1997, Mapping of the primary binding site of measles virus to its receptor CD46. J. Biol. Chem. 272:22072–22079.

    Article  PubMed  CAS  Google Scholar 

  • Buckland, R., Malvoisin, E., Beauverger, P., and Wild, F., 1992, A leucine zipper structure present in the measles virus fusion protein is not required for its tetramerization but is essential for fusion. J. Gen. Virol. 73:1703–1707.

    PubMed  CAS  Google Scholar 

  • Caballero, M., Carabana, J., Ortego, J., Femandez-Munoz, R., and Celma, M.L., 1998, Measles virus fusion protein is palmitoylated on transmembrane-intracytoplasmic cysteine residues which participate in cell fusion. J. Virol. 72:8198–8204.

    PubMed  CAS  Google Scholar 

  • Cathomen, T., Mrkic, B., Spehner, B., Drillien, R., Naef, R., Pavlovic, J., Aguzzi, A., Billeter, M. A., and Cattaneo, R., 1998a, A matrix-less measles virus is infectious and elicits extensive cell fusion: consequence for propagation in the brain. EMBO J. 17:3899–3908.

    Article  PubMed  CAS  Google Scholar 

  • Cathomen, T., Naim, H. Y., and R. Cattaneo, 1998b, Measles virus with altered envelope protein cytoplasmic tails gain cell fusion competence. J. Virol. 72:1224–1234.

    PubMed  CAS  Google Scholar 

  • Cattaneo, R., and Rose, J., 1993, Cell fusion by the envelope glycoproteins of persistent measles viruses that cause lethal human brain disease. J. Virol. 67:1497–1502.

    Google Scholar 

  • Cattaneo, R., Schmid, A., Eschle, D., Baczko, K., ter Meulen, V., and Billeter, M. A., 1988, Biased hypermutation and other genetic changes in defective measles viruses in human brain infections. Cell 55:255–265.

    Article  PubMed  CAS  Google Scholar 

  • Cattaneo, R., Schmid, A., Speilhofer, P., Kaelin, K., Baczko, K., ter Meulen, V., Pardowitz, J., Flanagan, S., Rima, B., Udem, S. A., and Billeter, M. A., 1989, Mutated and hypermutated genes of persistent measles viruses which caused lethal human brain diseases. Virology 173:415–425.

    Article  PubMed  CAS  Google Scholar 

  • Clements, C. J., and Cutts, F. T.; 1995; The epidemiology of measles: Thirty years of vaccination. In Measles virus (V. ter Meulen and M. A. Billeter, eds) Springer-Verlag, Berlin Heidelberg, pp. 13–30.

    Google Scholar 

  • Dorig R., E., Marcil, A., Chopra, A., and Richardson C., D., 1993, The human CD46 molecule is a receptor for measles virus (Edmonston strain). Cell 75:295–305.

    Article  PubMed  CAS  Google Scholar 

  • Egan, M. A., Carruth, L. M., Rowell, J. F., Yu, X., and Siliciano, R. F., 1996, Human immunodeficiency virus type I envelope protein endocytosis mediated by a highly conserved intrinsic internalization signal in the cytoplasmic tail of gp41 is suppressed in the presence of the Pr55gag precursor protein. J. Virol. 70:6547–6556.

    PubMed  CAS  Google Scholar 

  • Enders, J. F., and Peebles, T.C., 1954, Propagation in tissue cultures of cytopathogenic agents from patients with measles. Proc. Soc. Exp. Biol. Med. 86:277–286

    PubMed  CAS  Google Scholar 

  • Enders, J.F., 1962, Measles virus: historical review, isolation and behaviour in various systems. Am. J. Dis. Child. 103:282–287.

    PubMed  CAS  Google Scholar 

  • Fouillot-Coriou N, and Roux, L., 2000, Structure-function analysis of the Sendai virus F and HN cytoplasmic domain: different role for the two proteins in the production of virus particle. Virology 270:464–75.

    Article  PubMed  CAS  Google Scholar 

  • Gething, M. J., White, J. M., and Waterfield, M.D., 1978, Purification of Sendai virus: analysis of the NH2-terminal sequences generated during precursor activation. Proc. Natl. Acad. Sci. USA 75:2737–2740.

    PubMed  CAS  Google Scholar 

  • Giuffre, R. M., Tovell, D. R., Kay, C. M., and Tyrell, L. D. (1982). Evidence for an interaction between the membrane protein of a paramyxovirus and actin. J. Virol. 42:963–968.

    PubMed  CAS  Google Scholar 

  • Haase, A. T., Gantz, D., Eble, B. Walker, D., Stowring, L., Ventura, P., Blum, H., Wietgrefe, S., Zupanic, M., Tourtellotte, W., Gibbs, C. J., Norrby, E., and Rozenblatt, S., 1985, Natural history of restricted synthesis and expression of measles virus genes in subacute sclerosing panencephalitis. Proc. Natl. Acad. Sci. USA 82:3020–3024.

    PubMed  CAS  Google Scholar 

  • Hardwick, J. M., and Bussell, R. H., 1978, Glycoproteins of measles virus under reducing and non-reducing conditions. J. Virol. 25:687–692.

    PubMed  CAS  Google Scholar 

  • Hirano, A., Wang, A. H., Gombart, A. F., and Wong, T. C., 1992, The matrix protein of neurovirulent subacute scerosing panencephalitis virus and its acute measles progenitor are functionally different. Proc. Natl. Acad. Sci. U.S.A. 89:8745–8749.

    PubMed  CAS  Google Scholar 

  • Hsu, E. C., Sarangi, F., Iorio, C., Sidhu, M. S., Udem, S. A., Dillehay, D. L., Xu, W., Rota, P. A., Bellini, W. J., Richardson, C. D., 1998, A single amino acid change in the hemagglutinin protein of measles virus determines its ability to bind CD46 and reveals another receptor on marmoset B cells. J. Virol. 72:2905–2916.

    PubMed  CAS  Google Scholar 

  • Hu, A., Cattaneo, R., Schwarz, S., and Norrby, E., 1994, Role of N-linked oligosaccharide chains in the processing and antigenicity of measles virus haemagglutinin. J. Gen. Virol. 74: 1043–1053.

    Google Scholar 

  • Hu, A., and Norrby, E., 1994, Role of individual cysteine residues in the processing and antigenicity of the measles virus haemagglutinin protein. J. Gen. Virol. 75:2173–2181.

    PubMed  CAS  Google Scholar 

  • Hummel, K. B., and Bellini, W.J., 1995, Localization of monoclonal antibody epitopes and functional domains in the hemagglutinin protein of measles virus. J. Virol. 69:1913–1916.

    PubMed  CAS  Google Scholar 

  • Langedijk, J. P., Daus, F. J., and van Oirschot, J. T., 1997, Sequence and structure alignment of Paramyxoviridae attachment proteins and discovery of enzymatic activity for a morbillivirus hemagglutinin. J. Virol. 71:6155–6167.

    PubMed  CAS  Google Scholar 

  • Liszewski, K., and Atkinson, J. P., 1992, Membrane cofactor protein. Curr. Top. Microbiol. Immunol. 178:7–60.

    Google Scholar 

  • Maisner, A., Klenk, H.-D. and Herrler, G., 1998, Polarized budding of measles virus is not determined by viral glycoproteins. J. Virol. 72:5276–5278.

    PubMed  CAS  Google Scholar 

  • Maisner, A., Liszewski, M. K., Atkinson, J. P., Schwartz-Albiez, R. and Herrler, G., 1996, Two different cytoplasmic tails direct isoforms of the membrane cofactor protein (CD46) to the basolateral surface of Madin-Darby canine kidney cells. J. Biol. Chem. 271:18853–18858.

    PubMed  CAS  Google Scholar 

  • Maisner, A, Mrkic, B., Herrler, G., Moll, M., Billeter, M. A., Cattaneo, R., and Klenk, H.-D., 2000, Recombinant measles virus requiring an exogenous protease for activation of infectivity. J. Gen. Virol. 81:441–449.

    PubMed  CAS  Google Scholar 

  • Maisner, A., Zimmer, G., Liszewski, M. K., Lublin, M. D., Atkinson, J. P. and Herrler, G., 1997. “Membrane cofactor protein (MCP; CD46) is a basolateral protein that is not endocytosed: Importance of the tetrapeptide F-T-S-L at the carboxy terminus”. J. Biol. Chem. 272:20793–20799.

    Article  PubMed  CAS  Google Scholar 

  • Malvoisin, E., and Wild, F., 1993, Measles virus glycoproteins: studies on the structure and interaction of the haemagglutinin and fusion proteins. J. Gen. Virol. 74: 2365–2372.

    PubMed  CAS  Google Scholar 

  • Manie. S. N., Debreyene, D. S., Vincent, S., and Gerlier, D., 2000, Measles virus structural components are enriched into raft microdomains: Potential cellular location for virus assembly. J. Virol. 74, 305–311.

    Article  PubMed  CAS  Google Scholar 

  • Mebatsion, T., Konig, M., and Conzelmann, K. K., 1996, Budding of rabies virus particles in the absence of the spike glycoprotein. Cell 84:941–951.

    Article  PubMed  CAS  Google Scholar 

  • Miller, D. L., 1964, Frequency of complications of measles. Br. Med. J. 2;75–78.

    PubMed  CAS  Google Scholar 

  • Moll, M., Klenk, H.-D., Herrler, G., and Maisner, A., 2001, A single amino acid change in the cytoplasmic domains of measles virus glycoproteins H and F alters targeting, endocytosis and fusion in polarized Madin-Darby canine kidney cells. J. Biol. Chem., in press.

    Google Scholar 

  • Mottet, G., Müller, V., and Roux, L., 1999, Characterization of Sendai virus M protein mutants that can partially interfere with virus particle production. J. Gen. Virol. 80:2977–2986.

    PubMed  CAS  Google Scholar 

  • Nairn, H. Y., Ehler, E. and Billeter, M. A., 2000, Measles virus matrix protein specific apical virus release and glycoprotein sorting in epithelial cells. EMBO J. 19:3576–3585.

    Google Scholar 

  • Naniche, D., Varior-Krishnan, G., Cervoni, F., Wild T. F., Rossi, B., Rabourdin-Combe, C., and Gerlier, D., 1993, Human membrane cofactor protein (CD46) acts as a cellular receptor for measles virus. J. Virol. 67:6025–6032.

    PubMed  CAS  Google Scholar 

  • Ogura, H., Sato, H., Kamiya, S., and Nakamura, S., 1991, Glycosylation of measles virus haemagglutinin protein in infected cells. J. Gen. Virol. 72:2679–2684.

    PubMed  CAS  Google Scholar 

  • Paula-Barbosa, M. M., and Cruz, C., 1981, Nerve cell fusion in a case of subacute sclerosing panencephalitis. Ann. Neurol. 9:400–403.

    Article  PubMed  CAS  Google Scholar 

  • Peebles, 1991, Paramyxovirus M proteins. Pulling it all together and taking it on the road, In The Paramyxoviruses (Kingsbury, D.W., ed.) Plenum Press, New York, pp 427–456.

    Google Scholar 

  • Plemper, R. K., Hammond, A. L., and Cattaneo, R., 2000, Characterization of a region of the measles virus hemagglutinin sufficient for its dimerization. J. Virol. 74:6485–6493.

    Article  PubMed  CAS  Google Scholar 

  • Richardson, C. D., Scheid, A., and Choppin, P.W., 1980, Specific inhibition of paramyxovirus and myxovirus replication by oligopeptides with amino acid sequences similar to those at the N-termini of F1 or HA2 viral polypeptides. Virology 105:205–222.

    Article  PubMed  CAS  Google Scholar 

  • Riedl, P., Moll, M., Klenk, H.-D., and Maisner, A., 2001, Measles virus matrix protein is not cotransported with the viral glycoproteins but requires virus infection for efficient surface targeting. Virus Res., in press.

    Google Scholar 

  • Robbins, F.C., 1962, Measles clinical features. Pathogenesis, pathology, and complications. Am. J. Dis. Child. 102:266–273.

    Google Scholar 

  • Rodriguez-Boulan, E. and Nelson, W. J., 1989, Morphogenesis of the polarized epithelial cell phenotype. Science 245:718–725.

    PubMed  CAS  Google Scholar 

  • Roux, L., Beffy, P., and Portner, A., 1985, Three variations in the cell surface expression of the haemagglutinin-neuraminidase glycoprotein of Sendai virus. J. Gen. Virol. 66:987–1000.

    PubMed  CAS  Google Scholar 

  • Sanderson, C. M., McQueen, N. L., and Nayak, D. P., 1993, Sendai virus assembly: M protein binds to viral glycoprotein in transit through the secretory pathway. J. Virol. 67, 651–663.

    PubMed  CAS  Google Scholar 

  • Sato, T.A., Enami, M., and Kohama, T., 1995, Isolation of the measles virus hemagglutinin protein in a soluble form by protease digestion. J. Virol. 69:513–516.

    PubMed  CAS  Google Scholar 

  • Scheiffele, P., Roth, M. G., and Simons, K., 1997, Interaction of influenza haemagglutinin with sphinogilipid-cholesterol membrane domains via its transmembrane domain. EMBO J. 16, 5501–5508

    Article  PubMed  CAS  Google Scholar 

  • Schlender, J., Schnorr, J. J., Spielhofer, P., Cathomen, T., Cattaneo, R., Billeter, M., ter Meulen, V., and Schneider-Schaulies, S., 1996, Interaction of measles virus glycoproteins with the surface of uninfected peripheral blood lymphocytes induces immunosuppression in vitro. Proc. Natl. Acad. Sci. USA 93: 13194–13199.

    Article  PubMed  CAS  Google Scholar 

  • Spielhofer, P., Bächi, T., Fehr, T., Christiansen, G., Cattaneo, R., Kaelin, K.., Billeter, M. A., and Naim, H. Y., 1998, Chimeric measles virus with a foreign envelope. J. Virol. 72:2150–2159.

    PubMed  CAS  Google Scholar 

  • Stallcup, K. C., Raine, C. S., and Fields, B. N., 1983, Cytocholasin B inhibits the maturation of measles virus. Virology 124:59–74.

    Article  PubMed  CAS  Google Scholar 

  • Stricker, R., Mottet, G., and Roux, L., 1994, The Sendai virus matrix protein appears to be recruited in the cytoplasm by the viral nucleocapsid to function in viral assembly and budding. J. Gen. Virol. 75:1031–1042.

    PubMed  CAS  Google Scholar 

  • Suryanarayana, K., Baczko, K., ter Meulen, V., and Wagner, R. R., 1994, Transcription inhibition and other properties of matrix proteins expressed by M genes cloned from measles virus and diseased human brain tissue. J. Virol. 68:1532–1543.

    PubMed  CAS  Google Scholar 

  • Takeda, M., Takeuchi, K., Miyajima, N., Kobune, F., Ami, Y., Nagata, N., Suzari, Y., Nagai, Y., and Tashiro, M., 2000, Recovery of pahogenic measles virus from cloned cDNA. J. Virol. 74:6643–6647.

    Article  PubMed  CAS  Google Scholar 

  • Tatsuo, H., Ono, N., Tanaka, K., Yanagi Y., 2000, SLAM (CDw150) is a cellular receptor for measles virus. Nature 406:893–897.

    PubMed  CAS  Google Scholar 

  • Ter Meulen, V., Stephenson, J. R., and Kreth, H. W., 1983, Subacute sclerosing panencephalitis. Compr. Virol. 18:105–185.

    Google Scholar 

  • Tucker, S. P., and Compans, R. W., 1993, Virus infection of polarized epithelial cells. Adv. Virus Res. 42:187–247.

    PubMed  CAS  Google Scholar 

  • Tyrell, D. L. J., and Ernst, A., 1979, Transmembrane communication in cells chronically infected with measles virus. J. Cell. Biol. 81:396–402.

    Google Scholar 

  • Udem, S.A., 1984, Measles virus:conditions for the propagation and purification of infectious virus in high yield. J. Virol. Methods 8:123–136.

    PubMed  CAS  Google Scholar 

  • Varsanyi, T. M., Utter, G., and Norrby, E., 1984, Purification, morphology, and antigenic characterization of measles virus envelope proteins. J. Gen. Virol. 65:335–366.

    Article  Google Scholar 

  • Vincent, S., Gerlier, D., and Manié, S. N., 2000, Measles virus assembly within membrane rafts. J. Virol. 74:9911–9915.

    Article  PubMed  CAS  Google Scholar 

  • Von Messling, V., Zimmer, G., Herrler, G., Haas, L., and Cattaneo, R., 2001. The hemagglutinin of canine distemper virus determines tropism and cytopathogenicity. J. Virol. 75:6418–6427.

    Google Scholar 

  • Weidmann, A., Maisner, A., Garten, W., Seufert, M., ter Meulen, V., and Schneider-Schaulies, S., 2000. Proteolytic cleavage of the fusion protein but not membrane fusion is required for measles virus-induced immunosuppression in vitro. J. Virol. 74:1985–1993.

    PubMed  CAS  Google Scholar 

  • Wild T. F., Malvoisin, E., and Buckland, R., 1991, Measles virus: both the haemagglutinin and fusion glycoproteins are required for fusion. J. Gen. Virol. 72:439–442.

    PubMed  CAS  Google Scholar 

  • Wild, T. F, Fayolle, J., Beauverger, P., and Buckland, R., 1994. Measles virus fusion: role of the cysteine-rich region of the fusion glycoprotein. J. Virol. 68:7546–7548.

    PubMed  CAS  Google Scholar 

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  1. Institute of Virology, Philipps University Marburg, Robert-Koch-Str. 17, D-35037, Marburg, Germany

    Andrea Maisner

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  1. Microscopy and Imaging Center Department of Biology Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas

    Andreas Holzenburg

  2. Institut für Klinische and Molekulare Virologie, Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, Germany

    Elke Bogner

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Maisner, A. (2002). Role of Envelope Proteins in Measles Virus Assembly. In: Holzenburg, A., Bogner, E. (eds) Structure-Function Relationships of Human Pathogenic Viruses. Springer, Boston, MA. https://doi.org/10.1007/0-306-47650-9_7

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  • DOI: https://doi.org/10.1007/0-306-47650-9_7

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