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Mycoplasmas of Humans

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Book cover Molecular Biology and Pathogenicity of Mycoplasmas

Abstract

Although the mollicute responsible for contagious bovine peripneumonia, was isolated in 1898 (for an historical perspective see (13)), the first mycoplasma species (M. hominis) from humans was only recovered in 1937. In the 1940’s, Monroe Eaton identified the agent (later named M. pneumoniae) of primary atypical pneumonia. In 1981, M. genitalium, now recognized as a common cause of nongonoccocal urethritis (NGU), was isolated from urethral swabs collected from men with this clinical condition (144) and in the last decade, M. penetrans was isolated in urine samples from HIV-infected patients (75). This progressive but slow discovery of the human mycoplasma flora is due to the fastidious growth of these bacteria which require special media and which, in many cases, are particularly difficult to culture from clinical samples. Consequently, although their detection greatly benefited from the development of PCR-based methods (see “Diagnosis of mycoplasmal infections”, S. Razin), some of the aspects of mycoplasma pathogenesis in humans are still a matter of debate.

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  1. INRA, IBVM, 71 avenue Edouard Bourleaux, BP 81, 33883, Villenave D’Ornon, France

    Alain Blanchard

  2. Laboratoire de Bactériologie, Université Victor Segalen Bordeaux 2, 146 rue Léo Saignat, 33076, Bordeaux cedex, France

    Cécile M. Bébéar

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  1. The Hebrew University-Hadassah Medical School, Jerusalem, Israel

    Shmuel Razin

  2. University of Heidelberg, Heidelberg, Germany

    Richard Herrmann

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Blanchard, A., Bébéar, C.M. (2002). Mycoplasmas of Humans. In: Razin, S., Herrmann, R. (eds) Molecular Biology and Pathogenicity of Mycoplasmas. Springer, Boston, MA. https://doi.org/10.1007/0-306-47606-1_3

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