Skip to main content

Gene Delivery as a New Therapeutic Approach

  • Chapter
Integrated Biomaterials Science

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 259.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 379.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 329.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Boussif, O., Zanta, M.A., Mergny, M.D., Scherman, D., Demeneix, B., Behr, J.P. 1995. A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine, Proc. Natl. Acad. Sci. USA 92, 7297–7301.

    Google Scholar 

  • Chang, P.L. 1997. Microcapsules as bio-organs for somatic gene therapy, Ann. NY Acad. Sci. 831, 461–473.

    Google Scholar 

  • Earnshaw, D.J., Gait, M.J. 1997. Progress toward the structure and therapeutic use of the hairpin ribozyme, Antisense Nucleic Acid Drug Dev. 7, 403–411.

    Google Scholar 

  • Felgner, P.L., Barenholz, Y., Behr, J.P., Cheng, S.H., Cullis, P., Huang, L., Jessee, J.A., Seymour, L., Szoka, F., Thierry, A.R., Wagner, E., Wu, G. 1997. Nomenclature for synthetic gene delivery systems [editorial], Hum. Gene Ther. 8, 511–512.

    Google Scholar 

  • Felgner, P.L., Gadek, T.R., Holm, M., Roman, R., Chan, H.W., Wenz, M., Northrop, J.P., Ringold, G.M., Danielsen, M. 1987. Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure.

    Google Scholar 

  • Gibson, I. 1996. Antisense approaches to the gene therapy of cancer — “Recnac,” Cancer Metastasis Rev. 15, 287–299.

    Google Scholar 

  • Huang, L., Hung, M.C., Wagner, E. (eds). 1999. Nonviral Vectors for Gene Therapy, Academic Press, San Diego.

    Google Scholar 

  • Kren, B.T., Metz, R., Kumar, R., Steer, C.J. 1999. Gene repair using chimeric RNA/DNA oligonucleotides, Semin. Liver Dis. 19, 93–104.

    Article  Google Scholar 

  • Nielsen, P.E. 2000. Peptide nucleic acids: on the road to new gene therapeutic drugs, Pharmacol. Toxicol 86, 3–7.

    Article  Google Scholar 

  • Rizzuto, G., Cappelletti, M., Maione, D., Savino, R., Lazzaro, D., Costa, P., Mathiesen, I., Cortese, R., Ciliberto, G., Laufer, R., Monica, N., Fattori, E. 1999. Efficient and regulated erythropoietin production by naked DNA injection and muscle electroporation, Proc. Natl. Acad. Sci. USA 96, 6417–6422.

    Article  Google Scholar 

  • Vitiello, L., Chonn, A., Wasserman, J.D., Duff, C, Worton, R.G. 1996. Condensation of plasmid DNA with polylysine improves liposome-mediated gene transfer into established and primary muscle cells, Gene Ther. 3, 396–404.

    Google Scholar 

  • Wagner, E., Zatloukal, K., Cotton, M., Kirlappos, H., Mechtler, K., Curiel, D.T., Birnstiel, ML. 1992. Coupling of adenovirus to transferrin-polylysine/DNA complexes greatly enhances receptor-mediated gene delivery and expression of transfected genes, Proc. Natl. Acad. Sci. USA 89, 6099–6103.

    Google Scholar 

  • Wheeler, J.J., Palmer, L., Ossanlou, M., MacLachlan, I., Graham, R.W., Zhang, Y.P., Hope, M.J., Scherrer, P., Cullis, P.R. 1999. Stabilized plasmid-lipid particles: construction and characterization, Gene Ther. 6, 271–281.

    Article  Google Scholar 

  • Zanta, M.A., Belguise Valladier, P., Behr, J.P. 1999. Gene delivery: a single nuclear localization signal peptide is sufficient to carry DNA to the cell nucleus, Proc. Natl. Acad. Sci. USA 96, 91–96.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2002 Kluwer Academic Publishers

About this chapter

Cite this chapter

Vitiello, L., Veronese, F.M. (2002). Gene Delivery as a New Therapeutic Approach. In: Barbucci, R. (eds) Integrated Biomaterials Science. Springer, Boston, MA. https://doi.org/10.1007/0-306-47583-9_30

Download citation

  • DOI: https://doi.org/10.1007/0-306-47583-9_30

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-0-306-46678-6

  • Online ISBN: 978-0-306-47583-2

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics