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Epidemiology in the Courtroom

Dissonant Goals, Divergent Processes

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Case Studies in Forensic Epidemiology
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Abstract

The task before us is more daunting still when the dispute concerns matters at the very cutting edge of scientific research, where fact meets theory and certainty dissolves into probability. As the record in this case illustrates, scientists often have vigorous and sincere disagreements as to what research methodology is proper, what should be accepted as sufficient proof for the existence of a “fact,” and whether information derived by a particular method can tell us anything useful about the subject under study (Judge Alex Kozinski, Daubert v. Merrell-Dow Pharmaceuticals, Inc., 1995: 43 F.3d at 1316).

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References

  • Allen v. United States (1984), 588 F. Supp. 247 (D. Utah), reversed on other grounds, 816 F.2d 1417 (10th Cir. 1987), cert. denied, 484 U.S. 1004 (1988).

    Google Scholar 

  • Anderson v. Owens-Corning Fiberglass Corp. (1991). 810 P.2d 549.

    Google Scholar 

  • Beauchamp, T. L. (1996). Moral foundations. In S. S. Coughlin, T. L. Beauchamp (Eds.). Ethics and Epidemiology (pp. 24–52). New York: Oxford University Press.

    Google Scholar 

  • Black, B., Jacobson, J. A., Madeira, E. W. Jr., and See, A. (1997). Guide to epidemiology. In B. Black and P. W. Lee (Eds.), Expert Evidence: A Practitioner’s Guide to Law, Science, and the FJC Manual (pp. 73–115). St. Paul, Minnesota: West Group.

    Google Scholar 

  • Carrigan, J. R. (1995). Junk science and junk research. Trial Lawyers Guide, 39, 230–254.

    Google Scholar 

  • Carter, K. C. (1985). Koch’s postulates in relation to the work of Jacob Henle and Edwin Klebs. Medical History, 29, 353–374, 356–357.

    CAS  PubMed  Google Scholar 

  • Chaulk v. Volkswagen of America, Inc. (1986). 808 F.2d 639 (7th Cir.).

    Google Scholar 

  • Checkoway, H., & Demers, D. A. (1994). Occupational case-control studies. Epidemiologic Reviews, 16, 151–162.

    CAS  PubMed  Google Scholar 

  • Cole, P. (1991). The epidemiologist as an expert witness. Journal of Clinical Epidemiology, 44, supp. 1, 35S–39S.

    PubMed  Google Scholar 

  • Comstock, G. W. (1994). Evaluating vaccination effectiveness and vaccine efficacy by means of case control studies. Epidemiologic Reviews, 16, 77–89.

    CAS  PubMed  Google Scholar 

  • Cook, R. R. (1994). Transcript of videotaped deposition, June 14, in Ruth Johnson et al. v. Dow Corning et al., No. 254–93, District Court, Johnson County, Texas.

    Google Scholar 

  • Copeland, K. T., Checkoway, H., McMichael, A. J., & Holbrook, R. H. (1977). Bias due to misclassification in the estimation of relative risk. American Journal of Epidemiology, 105, 488–495.

    CAS  PubMed  Google Scholar 

  • Coughlin, S. S. (1990). Recall bias in epidemiologic studies. Journal of Clinical Epidemiology, 43, 87–91.

    CAS  PubMed  Google Scholar 

  • Daubert v. Merrell-Dow Pharmaceuticals, Inc. (1993). 509 U.S. 579, 113 S.Ct. 2786, 125 L.Ed.2d 469.

    Google Scholar 

  • Daubert v. Merrell-Dow Pharmaceuticals, Inc. (1995). 43 F.231311 (9th Cir.).

    Google Scholar 

  • Diamond, S., & Casper, J. (1992). Blindfolding the jury to verdict consequences: Damages, experts, and the civil jury, Law and Society Review, 26, 513–563.

    Google Scholar 

  • Dwyer, D. M., Strickler, H., Goodman, R. A., & Armenian, H. K. (1994). Use of case-control studies in outbreak investigations, Epidemiologic Reviews, 16, 109–123.

    CAS  PubMed  Google Scholar 

  • Farrar, W. B. (1991). Clinical trials: Access and reimbursement. Cancer, 67, 1779–1782.

    CAS  PubMed  Google Scholar 

  • Federal Rules of Civil Procedure 26, 56.

    Google Scholar 

  • Federal Rules of Evidence 401, 403, 702.

    Google Scholar 

  • Felson, D. T. (1992). Bias in meta-analytic research. Journal of Clinical Epidemiology, 45, 885–892.

    Article  CAS  PubMed  Google Scholar 

  • Fitzpatrick, J. M. & Shainwald, S. (1996). Breast Implant Litigation. New York: Law Journal Seminars-Press.

    Google Scholar 

  • Gold, S. (1986), Causation in toxic torts: The burdens of proof, standards of persuasion, and statistical evidence. Yale Law Journal, 96, 376–402.

    Google Scholar 

  • Gore, S. M. (1981). Assessing clinical trials—why randomise? British Medical Journal, 282, 1958–1960.

    CAS  PubMed  Google Scholar 

  • Gray-Donald, K., & Kramer, M. S. (1988). Causality inference in observational vs. experimental studies: An empirical comparison, American Journal of Epidemiology, 127, 885–892.

    CAS  PubMed  Google Scholar 

  • Greenland, S. (1977). Response and follow-up bias in cohort studies. American Journal of Epidemiology, 106, 184–187.

    CAS  PubMed  Google Scholar 

  • Greenland, S., & Robins, J. M. (1985). Confounding and misclassification. American Journal of Epidemiology, 122, 495–506.

    CAS  PubMed  Google Scholar 

  • Hammond, E. C., Selikoff, I. J., & Seidman, H. (1979). Asbestos exposure, cigarette smoking, and death rates. Annals of the New York Academy of Science, 330, 473–490.

    CAS  Google Scholar 

  • Hill, A. B. (1965). The environment and disease: Association or causation? Proceedings of the Royal Society of Medicine, 58, 295–300.

    CAS  PubMed  Google Scholar 

  • Hills, M., & Armitage, P. (1979). The two-period cross-over clinical trial. British Journal of Clinical Pharmacology, 8, 7–20.

    CAS  PubMed  Google Scholar 

  • Hymowitz v. Eli Lilly & Co., 73 N.Y.2d 487, cert. denied, 493 U.S. 944 (1989).

    Google Scholar 

  • Glantz, S. A., Slade, J., Bero, L. A., Hanauer, P., and Barnes, D. E. (1996). The Cigarette Papers. Berkeley, California: University of California Press.

    Google Scholar 

  • In re Agent Orange Products Liability Litigation (1984), 597 F. Supp. 740 (E.D.N.Y.), 603 F. Supp. 239 (E.D.N.Y. 1985); 611 F. Supp. 1223 (E.D.N.Y.), affirmed 818 F.2d 187 (2d Cir. 1987).

    Google Scholar 

  • In re Air Crash Disater at New Orleans, La (1986), 795 F.2d 1230 (5th Cir.).

    Google Scholar 

  • In re Bendectin Litigation (1988), 857 F.2d 290 (6th Cir.), cert. denied, 1989 US LEXIS 168.

    Google Scholar 

  • In re Joint Eastern and Southern Asbestos Litigation (1993), 827 F. Supp. 1014 (S.D.N.Y.), reversed, 52 F.3d 1124 (2d Cir. 1995).

    Google Scholar 

  • In re Silicone Gel Breast Implant Products Liability Litigation (1994). Master File No. CV 92-P-10000-S, interrogatories reprinted in S.M. Mackauf. (1994). Breast Implant Litigation: Current Medical and Legal Theories. New York: New York Law Publishing Company.

    Google Scholar 

  • In re TMI Litigation Cases Consolidated II (1996). 922 F. Supp. 997 (M.D. Pa.).

    Google Scholar 

  • Jooste, P. L., Yach, D., Steenkamp, H. J., Botha, J. L., & Rossouw, J. E. (1990). Drop-out and newcomer bias in a community cardiovascular follow-up study. International Journal of Epidemiology, 19, 284–289.

    CAS  PubMed  Google Scholar 

  • Karns, E. (1994). Understanding epidemiological evidence: What to ask the expert witness. Trial, 30, 48.

    Google Scholar 

  • Keeton, P. et al. (1984). Prosser and Keeton on the Law of Torts, 5th ed. St. Paul, Minnesota: West Publishing.

    Google Scholar 

  • Kehm v. Procter and Gamble Manufacturing Company (1983), 724 F.2d 613 (8th Cir.).

    Google Scholar 

  • Kelsey, J. L., Thompson, W. D., & Evans, A. S. (1986). Methods in Observational Epidemiology. New York: Oxford University Press.

    Google Scholar 

  • Khlat, M. (1994). Use of case-control methods for indirect estimation in demography. Epidemiologic Reviews, 16, 124–133.

    CAS  PubMed  Google Scholar 

  • Khoury, M. J., & Terri H., Beaty, T. H. (1994). Applications of the case-control method in genetic epidemiology. Epidemiologic Reviews, 16, 134–150.

    CAS  PubMed  Google Scholar 

  • Kleinbaum, D. G., Kupper, L. L., & Morgenstern, M. (1982). Epidemiologic Research: Principles and Quantitative Methods. New York: Van Nostrand Reinhold.

    Google Scholar 

  • Landrigan v. Celotex Corp. (1992), 605 A.2d 1079 (N.J.).

    Google Scholar 

  • Lasky, T., & Stolley, P. D. (1994). “Selection of cases and controls,” Epidemiologic Reviews, 16, 6–17.

    CAS  PubMed  Google Scholar 

  • Last, J. M., ed. (1988). A Dictionary of Epidemiology, 2nd ed. New York: Oxford University Press.

    Google Scholar 

  • Liberati, A. (1995). “Meta-analysis: statistical alchemy for the 21st century”: Discussion. A plea for a more balanced view of meta-analysis and systematic overviews of the effect of health care interventions. Journal of Clinical Epidemiology, 48, 81–86.

    Article  CAS  PubMed  Google Scholar 

  • Loue, S. (1999). Forensic Epidemiology: A Comprehensive Guide for Legal and Epidemiology Professionals. Carbondale, Illinois: Southern Illinois University Press.

    Google Scholar 

  • Lubin, J. H., & Gail, M. H. (1984). Biased selection of controls for case-control analyses of cohort studies, Biometrics, 40, 63–75.

    CAS  PubMed  Google Scholar 

  • Macklin, R. (1999). Ethics, epidemiology, and law: The case of silicone breast implants. American Journal of Public Health, 89, 487–489.

    CAS  PubMed  Google Scholar 

  • Marcus, R. L., & Rowe, T. D., Jr. (1994). Gilbert Law Summaries: Civil Procedure. Chicago: Harcourt Brace Legal and Professional Publications, Inc.

    Google Scholar 

  • Marder v. G. D. Searle and Co. (1986), 630 F. Supp. 1087 (D. Md.), affirmed 814 F.2d 655 (4th Cir. 1987).

    Google Scholar 

  • Matson, J. V. (1994). Effective Expert Witnessing, 2d ed. Boca Raton, Florida: Lewis Publishers.

    Google Scholar 

  • Mauro v. Raymark Industries, Inc., 561 A.2d 257 (N.J. 1989).

    Google Scholar 

  • Miettinen, O. S. (1985). The case-control study: Valid selection of subjects. Journal of Chronic Disease, 38, 543–548.

    Article  CAS  Google Scholar 

  • Miles, & J. Evans (Eds.), Demystifying Social Statistics (pp. 87–109). London: Pluto Press.

    Google Scholar 

  • Morabia, A. (1991). On the origin of Hill’s causal criteria. Epidemiology, 2, 367–369.

    CAS  PubMed  Google Scholar 

  • Morgenstern, H. (1996, Spring). Course Materials, Part II: Class Notes for Epidemiologic Methods II, Epidemiology, 201B, 54–82.

    Google Scholar 

  • Morgenstern, H. (1982). Uses of ecologic analysis in epidemiologic research. American Journal of Public Health, 72, 1336–1344.

    CAS  PubMed  Google Scholar 

  • Muscat, J. E., Huncharek, M. S. (1989). Causation and disease: Biomedical science in toxic tort litigation. Journal of Occupational Medicine, 31, 997–1002.

    CAS  PubMed  Google Scholar 

  • Novick, J. (1987). Use of epidemiological studies to prove legal causation: Aspirin and Reye’s syndrome, a case in point. Tort and Insurance Law Journal, 23, 536–557.

    Google Scholar 

  • O’Brien, P.C., & Shampo, M. A. (1988). Statistical considerations for performing multiple tests in a single experiment. 5. Comparing two therapies with respect to several endpoints. Mayo Clinic Proceedings, 63, 1140–1143.

    Google Scholar 

  • Olkin, I. (1995). Statistical and theoretical considerations in meta-analysis, quoting the National Library of Medicine, Journal of Clinical Epidemiology, 48, 133–146.

    Article  CAS  PubMed  Google Scholar 

  • Poole, C. (1987). Beyond the confidence interval. American Journal of Public Health, 77, 195–199.

    CAS  PubMed  Google Scholar 

  • Popper, K. R. (1968). The Logic of Scientific Discovery, 3rd ed. rev. New York: Harper and Row.

    Google Scholar 

  • Roht, L. H., Selwyn, B. J., Holguin, A. H., & Christensen, B. L. (1982), Principles of Epidemiology: A Self-Teaching Guide. New York: Academic Press, Inc.

    Google Scholar 

  • Rosner, F. (1987). The ethics of randomized clinical trials. American Journal of Medicine, 82, 283–290.

    Article  CAS  PubMed  Google Scholar 

  • Rothman, K. J. (1976). Causes, American Journal of Epidemiology, 104, 587–592.

    CAS  PubMed  Google Scholar 

  • Rothman, K. J. (1986). Modern Epidemiology. Boston: Little, Brown and Company.

    Google Scholar 

  • Sackett, D. L. (1979). Bias in analytic research. Journal of Chronic Diseases, 32, 51–63.

    Article  CAS  PubMed  Google Scholar 

  • Sanders, J. (1992), The Bendectin litigation: A case study in the life cycle of mass torts. Hastings Law Journal, 43, 301–418.

    Google Scholar 

  • Sartwell, P. E. (1960). On the methodology of investigations of etiologic factors in chronic disease further comments. Journal of Chronic Disease, 11, 61–63.

    Article  CAS  Google Scholar 

  • Schlesselman, J. J. (1982). Case Control Studies. New York: Oxford University Press.

    Google Scholar 

  • Schuck, P. H. (1987). Agent Orange on Trial: Mass Toxic Disasters in the Courts. Cambridge, Massachusetts: Belknap Press.

    Google Scholar 

  • Schwartz, T. M. (1988). The role of federal safety regulations in products liability actions. Vanderbilt Law Review, 41, 1121–1169.

    Google Scholar 

  • Selby, J. V. (1994). Case-control evaluations of treatment and program efficacy. Epidemiologic Reviews, 16, 90–101.

    CAS  PubMed  Google Scholar 

  • Senn, S. J. (1991). Falsification and clinical trials. Statistics in Medicine, 10, 1679–1692.

    CAS  PubMed  Google Scholar 

  • Shapiro, A. K., & Shapiro, E. (1997). The Powerful Placebo: From Ancient Priest to Modern Physician. Baltimore, Maryland: Johns Hopkins University.

    Google Scholar 

  • Sindell v. Abbott Laboratories, 26 Cal. 3d 588, cert. denied, 449 U.S. 912, 1980.

    Google Scholar 

  • Smith, P.G. (1983). Issues in the design of case-control studies: Matching and interaction effects. Tijdschrift voor Sociale Gezondheidszorg, 61, 755–760.

    Google Scholar 

  • Special Committee on Jury Comprehension of the American Bar Association Section of Litigation. (1989). Jury Comprehension in Complex Cases. Chicago: American Bar Association.

    Google Scholar 

  • Sterling, T. D., Weinkam, J. J., & Weinkam, J. L. (1990). The sick person effect. Journal of Clinical Epidemiology, 43, 141–151.

    Article  CAS  PubMed  Google Scholar 

  • Susser, M. (1986). The logic of Sir Karl Popper and the practice of epidemiology. American Journal of Epidemiology, 124, 711–718.

    CAS  PubMed  Google Scholar 

  • Susser, M. (1991). What is a cause and how do we know one? A grammar for pragmatic epidemiology. American Journal of Epidemiology, 133, 635–648.

    CAS  PubMed  Google Scholar 

  • Swan, S.S. (1994). Epidemiology of silicone-related disease. Seminars in Arthritis and Rheumatism, 24, 38–43.

    CAS  Google Scholar 

  • United States Attorney General. (1986). Report of the Tort Policy Working Group on the Causes, Extent, and Policy Implications of the Current Crisis in Insurance Availability and Affordability.

    Google Scholar 

  • Voke, B.P. (1994). Sources of proof of causation in toxic tort cases. Defense Counsel Journal, 61, 45–50.

    Google Scholar 

  • Wacholder, S., Silverman, D. T., McLaughlin, J. K., & Mandel, J. S. (1992). Selection of controls in case control studies. III. Design options. American Journal of Epidemiology, 135, 1042–1050.

    CAS  PubMed  Google Scholar 

  • Weed, D. L. (1986). On the logic of causal inference. American Journal of Epidemiology, 123, 965–979.

    CAS  PubMed  Google Scholar 

  • Weinstein, J. B. (1986). Improving expert testimony. University of Richmond Law Review, 20, 473–497.

    Google Scholar 

  • Weiss, N. S. (1994). Application of the case-control method in the evaluation of screening, Epidemiologic Reviews, 16, 102–108.

    CAS  PubMed  Google Scholar 

  • Windsor Shirt Company v. New Jersey National Bank (1992), 793 F. Supp. 589 (E.D. Pa.).

    Google Scholar 

  • 21 Code of Federal Regulations § 312.2l(a)(1998).

    Google Scholar 

  • 21 Code of Federal Regulations § 312.21(b)(1998).

    Google Scholar 

  • 21 Code of Federal Regulations § 312.21(c)(1998).

    Google Scholar 

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(2002). Epidemiology in the Courtroom. In: Case Studies in Forensic Epidemiology. Springer, Boston, MA. https://doi.org/10.1007/0-306-47524-3_1

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