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The Immunobiology of Hookworm Infection

  • Chapter
The Geohelminths: Ascaris, Trichuris and Hookworm

Part of the book series: World Class Parasites ((WCPA,volume 2))

Conclusions

The applied immunologist will remain interested in the strategies used by the hookworm parasites to modulate the human immune system.This knowledge will surely be used by the vaccinologist to further the quest for long-lasting protection against hookworm infection where infection intensities warrant intervention.These goals will be furthered by the selective exploitation of information becoming available from hookworm genomics initiatives and the application of functional genomics in the field. Furthermore,the fact that some hookworms have evolved to modulate immunity,to the extent that field studies are now beginning to show solid evidence for protective effects against atopic symptoms (Scrivener et al. 2001),raises the possibility that further hookworm products such as NIF may be exploited therapeutically (Rahman et al. 2000).

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Author information

Authors and Affiliations

  1. Boots Science Building, School of Pharmacy, University of Nottingham, UK

    D.I. Pritchard & A. Brown

  2. School of Biology, University of Leeds, UK

    R.J. Quinnell

  3. Department of Microbiology and Tropical Medicine, George Washington University, Washington, D.C., USA

    P.J. Hotez & J.M. Hawdon

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  1. D.I. Pritchard
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  3. P.J. Hotez
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  5. A. Brown
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  1. Department of Zoology, University of Dublin, Dublin

    Celia V. Holland

  2. Division of Environmental and Evolutionary Biology Institute of Biomedical and Life Sciences, University of Glasgow, Glasgow, UK

    Malcolm W. Kennedy

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© 2002 Kluwer Academic Publishers

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Pritchard, D., Quinnell, R., Hotez, P., Hawdon, J., Brown, A. (2002). The Immunobiology of Hookworm Infection. In: Holland, C.V., Kennedy, M.W. (eds) The Geohelminths: Ascaris, Trichuris and Hookworm. World Class Parasites, vol 2. Springer, Boston, MA. https://doi.org/10.1007/0-306-47383-6_9

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  • DOI: https://doi.org/10.1007/0-306-47383-6_9

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-0-7923-7557-9

  • Online ISBN: 978-0-306-47383-8

  • eBook Packages: Springer Book Archive

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