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References
Richardson, B., and Yung, R., 1999, Role of DNA methylation in the regulation of cell function. J. Lab. Clin. Med. 134: 333–340
Attadia, V., 1993, Effects of 5-aza-2′-deoxycytidine on differentiation and oncogene expression in the human monoblastic leukemia cell line U-937. Leukemia. 7 (Suppl. 1): 9–16
Saitoh, T., Hiraishi, K., Adachi, M., and Hozumi, M., 1995, Induction by 5-aza-2′-deoxycytidine, an inhibitor of DNA methylation, of Ley antigen, apoptosis and differentiation in human lung cancer cells. Anticancer Res. 15: 2137–2144
Creusot, F., Acs, G., and Christman, J.K., 1982, Inhibition of DNA methyltrans ferase and induction of Friend erythroleukemia cell differentiation by 5-azacyti-dine and 5-aza-2′-deoxycytidine. J. Biol. Chem. 257: 2041–2048
Wyczechowska, D., Ruckemann, K., Duley, J.A., Simmonds, A.H., and Fabianowska-Majewska, K., 1999, Distinct inhibitory effects of 2-chloro-2′-deoxy-adenosine and 9-□-D-arabinosyl-2-fluoroadenine in DNA methyltransferase in human T-lymphocytes. Nucleos. Nucleot. 18: 831–834
Wyczechowska, D., and Fabianowska-Majewska, K., 1998, Does 2-chlorodeoxy-adenosine contributed to alteration of DNA methyltransferase activity? Adv. Exp. Med. Biol. 431: 595–598
Orkin, S.H., Harosi, F.I., and Leder, P., 1975, Differentiation in erythroleukemic cells and their somatic hybrids. Proc. Nat. Acad.Sci. USA. 72: 98–102
Zardo, G., and Caiafa, P., 1998, The unmethylated state of CpG islands in mouse fibroblasts depends on the poly(ADP-ribosyl)ation process. J. Biol. Chem. 273: 16517–16520
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Fabianowska-Majewska, K., Wyczechowska, D., Czyz, M. (2002). Inhibition of DNA Methylation by 5-Aza-2′-Deoxycytidine Correlates with Induction of K562 Cells Differentiation. In: Zoref-Shani, E., Sperling, O. (eds) Purine and Pyrimidine Metabolism in Man X. Advances in Experimental Medicine and Biology, vol 486. Springer, Boston, MA. https://doi.org/10.1007/0-306-46843-3_66
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DOI: https://doi.org/10.1007/0-306-46843-3_66
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