Abstract
The cell ultrastructure and some detoxifying enzyme activities were studied in skeletal muscles of young rats kept for 84 h under normobaric hyperoxia (95% O2) or normoxia as control. Rat were injected ip. Every 12 h either with lml saline, 1 ml saline +30 mg hypotaurine or 1 ml saline +30 mg taurine. Ultrastructural observation revealed an highly protective effect on tissue damages due to hyperoxia in taurinetreated rats and, at less extent, in hypotaurine-treated ones. Enzymatic assays suggest a different mechanism of the two molecules in their protective action.
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Pitari, G., Duprè, S., Ragnelli, A.M., Aimola, P., Giulio, C.D., Amicarelli, F. (2002). Biochemical and Ultrastructural Alaterations is Rat After Hyperoxic Treatment: Effect of Taurine and Hypotaurine. In: Della Corte, L., Huxtable, R.J., Sgaragli, G., Tipton, K.F. (eds) Taurine 4. Advances in Experimental Medicine and Biology, vol 483. Springer, Boston, MA. https://doi.org/10.1007/0-306-46838-7_15
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DOI: https://doi.org/10.1007/0-306-46838-7_15
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