Skip to main content
SpringerLink
Log in

Measurements of Chromogranins and Chromogranin-Related Peptides by Immunological Methods

  • Chapter
Chromogranins

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 482))

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 129.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Bajetta, E., Ferrari, L., Martinetti, A., Celio, L., Procopio, G., Artale, S., Zilembo, N., Di Bartolomeo, M., Seregni, E., and Bombardieri, E., 1999, Chromogranin A, neuron specific enolase, carcinoembryonic antigen, and hydroxyindole acetic acid evaluation in patients with neuroendocrine tumors. Cancer 86: 858–865.

    Article  PubMed  CAS  Google Scholar 

  • Bender, H., Maier, A., Wiedenmann, B., O’Connor, D.T., Messner, K., and Schmidt, G.H., 1992, Immunoluminometric assay of chromogranin A in serum with commercially available reagents. Clin. Chem. 38: 2267–2272.

    PubMed  CAS  Google Scholar 

  • Corti, A., Gasparri, A., Chen, F. X., Pelagi, M., Brandazza, A., Sidoli, A., and Siccardi, A.G., 1996, Characterisation of circulating chromogranin A in human cancer patients. Brit. J. Cancer 73: 924–932.

    PubMed  CAS  Google Scholar 

  • Cunningham, R.T., Pogue, K.M., Curry, W.J., Johnston, C.F., Sloan, J.M., and Buchanan, K.D., 1999, Immunostaining for vasostatin I distinguishes between ileal and lung carcinoids. J. Pathol. 187: 321–325.

    Article  PubMed  CAS  Google Scholar 

  • Degorce, F., Goumon, Y., Jacquemart, L., Vidaud, C., Bellanger, L., Pons-Anicet, D., Seguin, P., Metz-Boutigue, M.H., and Aunis, D., 1999, A new human chromogranin A (CGA) immunoradiometric assay involving monoclonal antibodies raised against the unprocessed central domain (145–245). Brit. J. Cancer 79: 65–71.

    PubMed  CAS  Google Scholar 

  • Dillen, L., De Block, J., Van Lear, L., and De Potter, W., 1989, Enzyme-linked immunosorbent assay for chromogranin A. Clin. Chem. 35: 1934–1938.

    PubMed  CAS  Google Scholar 

  • Eriksson, B., Amberg, H., Oberg, K., Hellman, U., Lundquist, G., Wernstedt, C., and Wilander, E., 1990, A polyclonal antiserum against chromogranins A and B: A new sensitive marker for neuroendocrine tumors. Acta Endocrinol. 122: 145–155.

    PubMed  CAS  Google Scholar 

  • Hsiao, R.J., Mezger, M.S., and O’Connor, D.T., 1990a, Chromogranin A in uremia: Progressive retention of immunoreactive fragments. Kidney Internat. 37: 955–964.

    CAS  Google Scholar 

  • Hsiao, R.J., Neumann, H.P.H., Parmer, R.J., Barbosa, J.A., and O’Connor, D.T., 1990b, Chromogranin A in familial pheochromocytoma: Diagnostic screening value, prediction oftumor mass, and post-resection kinetics indicating two-compartment distribution. Am. J. Med. 88: 607–613.

    Article  PubMed  CAS  Google Scholar 

  • Iguchi, H., Natori, S., Kato, K., Nawata, H., and Chretien, M., 1988, Different processing of chromogranin B into GAWK-immunoreactive fragments in the bovine adrenal medulla and pituitary gland. Life Sci. 43: 1945–1952.

    Article  PubMed  CAS  Google Scholar 

  • Iguchi, H., Bannai, S., Takanashi, N., and Tsukada, Y., 1992, Production of chromogranin A and B derived peptides in human small cell lung carcinoma cell lines. Europ. J. Cancer 28A: 1458–1462.

    CAS  Google Scholar 

  • Janson, E. T., Holmberg, L., Stridsberg, M., Eriksson, B., Theodorsson, E., Wilander, E., and Oberg, K., 1997, Carcinoid tumors: analysis of prognostic factors and survival in 301 patients from a referral center. Ann. Oncol. 8: 685–690.

    Article  PubMed  CAS  Google Scholar 

  • Jensen, T. B., Hilsted, L., and Rehfeld, J. F., 1999, Library of sequence-specific radioimmunoassays for human chromogranin A. Clin. Chem. 45: 549–560.

    PubMed  CAS  Google Scholar 

  • Kawakubo, A., Takatsuki, K., Yoneda, M., Kurokawa, M., Suzuki, A., Semba, R., and Kato, K., 1989, Highly sensitive enzyme immunoassay for bovine chromogranin A: Application for studies of regional distribution in bovine central nervous system. J. Mol. Neurosci. 1: 215–224.

    PubMed  CAS  Google Scholar 

  • Kirchmair, R., Hogue Angeletti, R., Gutierrez, J., Fischer Colbrie, R., and Winkler, H., 1993, Secretoneurin: a neuropeptide generated in brain, adrenal medulla and other endocrine tissues by proteolytic processing of secretogranin II (chromogranin C). Neuroscience 53: 359–365.

    Article  PubMed  CAS  Google Scholar 

  • Kirchmair, R., Leitner, B., Fischer-Colbrie, R., Marksteiner, J., Hogue-Angeletti, R., and Winkler, H., 1995, Large variations in the proteolytic formation of a chromogranin A-derived peptide (GE-25) in neuroendocrine tissues. Biochem. J. 310: 331–336.

    PubMed  CAS  Google Scholar 

  • Marksteiner, J., Bauer, R., Kaufmann, W.A., Weiss, E., Barnas, U., and Maier, H., 1999, PE-11, a peptide derived from chromogranin B, in the human brain. Neuroscience 91: 1155–1170.

    Article  PubMed  CAS  Google Scholar 

  • McGrath-Linden, S.J., Johnston, C.F., O’Connor, D.T., Shaw, C., and Buchanan, K.D., 1991, Pancreastatin-like immunoreactivity in human carcinoid disease. Regul. Pept. 33: 55–70.

    Article  PubMed  CAS  Google Scholar 

  • Nagasawa, S., Nishikawa, Y., Jun L., Futai Y., Kanno T., Iguchi K., Mochizuki, T., Hoshino, M., Yanaihara, C., and Yanaihara, N., 1998, Simple enzyme immunoassay for the measurement of immunoreactive chromogranin A in human plasma, urine and saliva. Biomed. Res. 19: 407–410.

    CAS  Google Scholar 

  • Nishikawa, Y., Nagasawa, S., Yanaihara, N., Iguchi K., Mochizuki, T., Hoshino, M., Iwanaga, T., and Yanaihara, C., 1998a, Immunoreactive chromogranin A in rat plasma and urine measured by region-specific radioimmunoassay. Biomed. Res. 19: 237–244.

    CAS  Google Scholar 

  • Nishikawa, Y., Jun L., Futai Y., Yanaihara, N., Iguchi K., Mochizuki, T., Hoshino, M., and Yanaihara, C., 1998b, Region-specific radioimmunoassay for human chromogranin A. Biomed. Res. 19: 245–251.

    CAS  Google Scholar 

  • Nobels, F.R.E., Kwekkeboom, D.J., Coopmans, W., Hoekstra, R., De Herder, W.W., Bouillon, R., and Lamberts, S.W.J., 1993, A comparison between the diagnostic value of gonadotropins, a-subunit, and chromogranin-A and their response to thyrotropin-releasing hormone in clinically nonfunctioning, a-subunit-secreting, and gonadotroph pituitary adenomas. J. Clin. Endocrinol. Metabol. 77: 784–789.

    Article  CAS  Google Scholar 

  • Nobels, F.R., Kwekkeboom, D.J., Coopmans, W., Schoenmakers, C.H., Lindemans, J., De Herder, W. W., Krenning, E.P., Bouillon, R., and Lamberts, S.W., 1997, Chromogranin A as serum marker for neuroendocrine neoplasia: comparison with neuron-specific enolase and the alpha-subunit of glycoprotein hormones. J. Clin. Endocrinol. Metabol. 82: 2622–2628.

    Article  CAS  Google Scholar 

  • O’Connor, D.T., and Deftos, L.J., 1986, Secretion of chromogranin A by peptide-producing endocrine neoplasms. New England J. Med. 314: 1145–1151.

    Google Scholar 

  • O’Connor, D.T., Pandlan, M.R., Carlton, E., Cervenka, J.H., and Hsiao, R.J., 1989, Rapid radioimmunoassay of circulating chromogranin A in vitro stability, exploration of the neuroendocrine character of neoplasia, and assessment of the effects of organ failure. Clin. Chem. 35: 1631–1637.

    Google Scholar 

  • Sanduleanu, S., Stridsberg, M., Jonkers, D., Hameeteman, W., Biemond, I., Lundqvist, G., Lamers, C., and Stockbrugger, R.W., 1999, Serum gastrin and chromogranin A during meals. Alim. Pharmacol. Therap. 13: 145–153.

    CAS  Google Scholar 

  • Stridsberg, M., Hellman, U., Wilander, E., Lundqvist, G., Hellsing, K., and Dberg, K., 1993, Fragments of chromogranin A are present in the urine of patients with carcinoid tumours: Development of a specific radioimmunoassay for chromogranin A and its fragments. J. Endocrinol. 139: 329–337.

    Article  PubMed  CAS  Google Scholar 

  • Stridsberg, M., Dberg, K., Li, Q., Engstrom, U., and Lundqvist, G., 1995, Measurements of chromogranin A, chromogranin B (secretogranin I), chromogranin C (secretogranin II) and pancreastatin in plasma and urine from patients with carcinoid tumours and endocrine pancreatic tumours. J.f Endocrinol. 144: 49–59.

    CAS  Google Scholar 

  • Stridsberg, M. and Husebye, E.S., 1997, Chromogranin A and chromogranin B are sensitive circulating markers for phaeochromocytoma. Europ. J. Endocrinol. 136: 67–73.

    CAS  Google Scholar 

  • Syversen, U., Waldum, H.L., and O’Connor, D.T., 1992, Rapid, high-yield isolation of human chromogranin A from chromaffin granules of pheochromocytomas. Neuropeptides 22: 235–240.

    Article  PubMed  CAS  Google Scholar 

  • Takiyyuddin, M.A., Cervenka, J.H., Pandian, M.R., Stuenkel, C.A., Neumann, H.P., and O’Connor, D.T., 1990, Neuroendocrine sources of chromogranin-A in normal man: clues from selective stimulation of endocrine glands. J. Clin. Endocrinol. Metabol. 71: 360–369.

    CAS  Google Scholar 

  • Takiyyuddin, M.A., Baron, A.D., Cervenka, J.H., Barbosa, J.A., Neumann, H.P.H., Parmer, R.J., Sullivan, P.A., and O’Connor, D.T., 1991, Suppression of chromogranin A release from neuroendocrine sources in man: Pharmacological studies. J. Clin. Endocrinol. Metabol. 72: 616–622.

    CAS  Google Scholar 

  • Tateishi, K., Funakoshi, A., Wakasugi, H., Iguchi, H., Shinozaki, H., Abe, M., Funakoshi, S., Tamamura, H., Yajima, H., and Matsuoka, Y., 1989, Plasma pancreastatin-like immunoreactivity in various diseases. J. Clin. Endocrinol. Metabol. 69: 1305–1308.

    Article  CAS  Google Scholar 

  • Wassberg, E., Stridsberg, M., and Christofferson, R., 1996, Plasma levels of chromogranin A are directly proportional to tumour burden in neuroblastoma. J. Endocrinol. 151: 225–230.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Medical Sciences, University Hospital, Uppsala, Sweden

    Mats Stridsberg

Authors
  1. Mats Stridsberg
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. University of Bergen, Bergen, Norway

    Karen B. Helle

  2. INSERM U338, Centre of Neurochemistry, Strasbourg, France

    Dominique Aunis

Rights and permissions

Reprints and permissions

Copyright information

© 2002 Kluwer Academic Publishers

About this chapter

Cite this chapter

Stridsberg, M. (2002). Measurements of Chromogranins and Chromogranin-Related Peptides by Immunological Methods. In: Helle, K.B., Aunis, D. (eds) Chromogranins. Advances in Experimental Medicine and Biology, vol 482. Springer, Boston, MA. https://doi.org/10.1007/0-306-46837-9_25

Download citation

  • DOI: https://doi.org/10.1007/0-306-46837-9_25

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-0-306-46446-1

  • Online ISBN: 978-0-306-46837-7

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation