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Agneter, E., Sitte, H.H., Stöckl-Hiesleitner, S., Fischer-Colbrie, R., Winkler, H., and Singer, E.A., 1995, Sustained dopamine release induced by secretoneunn in the striatum of the rat: a microdialysis study. J. Neurochem. 65: 622–625.
Anouar, Y., Jégou, S., Alexandre, D., Lihrmann, I., Conlon, J.M., and Vaudry, H., 1996, Molecular cloning of frog secretogranin II reveals the occurrence of several highly conserved potential regulatory peptides. FEBS Lett. 394: 295–299.
Blázquez, M., Bosma, P.T., Chang, J.P., Docherty, K., and Trudeau, V.L., 1998, y-aminobutyric acid up-regulates the expression of a novel secretogranin-II messenger ribonucleic acid in the goldfish pituitary. Endocrinology 139: 4870–4880.
Dittie, A.S., and Tooze, S.A., 1995, Characterization of the endopeptidase PC2 activity towards secretogranin II in stably transfected PC12 cells. Biochem. J. 310: 777–787.
Dun, N.J., Dun, S.L., Lin, H.H., Hwang, L.L., Saria, A., and Fischer-Colbne, R., 1997, Secretoneurin-like immunoreactivity in rat sympathetic, enteric and sensory ganglia. Brain Res. 760: 8–16.
Dunzendorfer, S., Schratzberger, P., Reinisch, N., Kähler, C.M., and Wiedermann, C.J., 1998, Secretoneurin, a novel neuropeptide, is a potent chemoattractant for human eosinophils. Blood 91: 1527–1532.
Eder, U., Fischer-Colbne, R., Kogner, P., Leitner, B., Bjellerup, P., and Winkler, H., 1998, Levels and molecular forms of chromogranins in human childhood neuroblastomas and ganglioneuromas. Neurosci Lett 253: 17–20.
Fischer-Colbne, R., Gutierrez, J., Hsu, C. M., Iacangelo, A., and Eiden, L.E., 1990, Sequence analysis, tissue distribution and regulation by cell depolarization, and second messengers of bovine secretogranin II (chromogranin C) mRNA. J. Biol. Chem. 265: 9208–9213.
Fischer-Colbne, R., Laslop, A., and Kirchmair, R., 1995, Secretogranin II: molecular properties, regulation of biosynthesis and processing to the neuropeptide secretoneurin. Prog. Neurobiol. 46: 49–70.
Fujita, Y., Katagi, J., Tabuchi, A., Tsuchiya, T., and Tsuda, M., 1999, Coactivation of secretogranin-II and BDNF genes mediated by calcium signals in mouse cerebellar granule cells. Mol. BrainRes. 63: 316–324.
Gruber, B., Schratzberger, P., Kähler, C. M., Dunzendorfer, S., Bellmann, R., Reinisch, N., and Wiedermann, C.J., 1997, Staurosporine-dependent activation of human endothelial cell monolayers for neutrophil adherence by secretoneurin. Peptides 18: 1445–1447.
Hoflehner, J., Eder, U., Laslop, A., Seidah, N.G., Fischer-Colbrie, R., and Winkler, H., 1995, Processing of secretogranin II by prohormone convertases: importance of PCl in generation of secretoneunn. FEBS Lett. 360: 294–298.
Holthuis, J.C.M., and Martens, G.J.M., 1996, The neuroendocrine proteins secretogranin II and III are regionally conserved and coordinately expressed with proopiomelanocortin in Xenopus intermediate pituitary. J. Neurochem. 66: 2248–2256.
Iacangelo, A.L., and Eiden, L.E., 1995, Chromogranin A: current status as a precursor for bioactive peptides and a granulogenic/sorting factor in the regulated secretory pathway. Regul. Pept. 58: 65–88.
Ischia, R., Gasser, R.W., Fischer-Colbrie, R., Eder, U., Pagani, A., Cubeddu, L.X., Lovisetti-Scamihom, P., Finkenstedt, G., Laslop, A., and Winkler, H., 2000, Levels and molecular propertiesof secretoneurin-immunoreactivity in the serum and urine of control and neuroendocrine tumor patients. J. Clin. Endocrinol. Metab. 85: 355–360.
Kähler, C.M., Bellmann, R., Reinisch, N., Schratzberger, P., Gruber, B., and Wiedermann, C.J., 1996, Stimulation of human skin fibroblast migration by the neuropeptide secretoneurin. Eur. J. Pharmacol. 304: 135–139.
Kähler, C. M., Kaufmann, G., Hogue-Angeletti, R., Fischer-Colbrie, R., Dunzendorfer, S., Reinisch, N., and Wiedermann, C.J., 1999, A soluble gradient of the neuropeptide secretoneurin promotes the transendothelial migration of monocytes in vitro. Eur. J. Pharmacol. 365: 65–75.
Kähler, C.M., Kirchmair, R., Kaufmann, G., Kähler, S.T., Reinisch, N., Fischer-Colbrie, R., Hogue-Angeletti, R., Winkler, H., and Wiedermann, C.J., 1997a, Inhibition of proliferation and stimulation of migration of endothelial cells by secretoneurin in vitro. Arterioscler. Thromb. Vasc. Biol. 17: 932–939.
Kähler, C.M., Schratzberger, P., and Wiedermann, C.J., 1997b, Response of vascular smooth muscle cells to the neuropeptide secretoneurin. A fuctional role for migration and proliferation in vitro. Arterioscler. Thromb. Vasc. Biol. 17: 2029–2035.
Kirchmair, R., Hogue-Angeletti, R., Gutierrez, J., Fischer-Colbrie, R., and Winkler, H., 1993, Secretoneurin — a neuropeptide generated in brain, adrenal medulla and other endocrine tissues by proteolytic processing of secretogranin II (chromogranin C). Neuroscience 53: 359–365.
Kirchmair, R., Marksteiner, J., Troger, J., Mahata, S.K., Mahata, M., Donnerer, J., Amann, R., Fischer-Colbrie, R., Winkler, H., and Saria, A., 1994, Human and rat primary C-fibre afferents store and release secretoneurin, a novel neuropeptide. Eur. J. Neurosci. 6: 861–868.
Kong, C., Gill, B.M., Rahimpour, R., Xu, L., Feldman, R.D., Xiao, Q., McDonald, T.J., Taupenot, L., Mahata, S.K., Singh, B., O’Connor, D.T., and Kelvin, D.J., 1998, Secretoneurin and chernoattractant receptor interactions. J. Neuroimmunol. 88: 91–98.
Kroesen, S., Marksteiner, J., Mahata, S.K., Mahata, M., Fischer-Colbrie, R., Saria A., Kapeller, I., and Winkler, H., 1995, Effects of haloperidol, clozapine and citalopram on messenger RNA levels of chromogranins A and B and secretogranin II in various regions of rat brain. Neuroscience 69: 881–891.
Laslop, A., and Tschemitz, C., 1992, Effects of nerve growth factor on the biosynthesis of chromogranin A and B, secretogranin II and carboxypeptidase H in rat PC12 cells. Neuroscience 49: 443–450.
Leitner, B., Fischer-Colbrie, R., Scherzer, G., and Winkler, H., 1996, Secretogranin II: relative amounts and processing to secretoneurin in various rat tissues. J. Neurochem. 66: 1312–1317.
Leitner, B., Schneitler, C., Klocker, H., Volknandt, W., Zimmermann, H., Winkler, H., and Fischer-Colbrie, R., 1998, Formation and sequence analysis of secretoneurin, a neuropeptide derived from secretogranin II, in mammalian, bird, reptile, amphibian and fish brains. Neurosci. Lett. 248: 105–108.
Li, J.Y., Leitner, B., Lovisetti-Scamihorn, P., Winkler, H., and Dahlström, A., 1999, Proteolytic processing, axonal transport and differential distribution of chromogranins A and B, and secretogranin II (secretoneurin) in rat sciatic nerve and spinal cord. Eur. J. Neurosci. 11: 528–544.
Mahata, S.K., Kozak, C.A., Szpirer, J., Szpirer, C., Modi, W.S., Gerdes, H.H., Huttner, W.B., and O’Connor, D.T., 1996, Dispersion of chromogranidsecretogranin secretory protein family loci in mammalian genomes. Genomics 33: 135–139.
Mahata, S.K., Marksteiner, J., Sperk, G., Mahata, M., Gruber, B., Fischer-Colbrie, R., and Winkler, H., 1992, Temporal lobe epilepsy of the rat: differential expression of mRNAs of chromogranin B, secretogranin II, synaptin/synaptophysin and p65 in subfields of the hippocampus. Mol. BrainRes. 16: 1–12.
Marksteiner, J., Kirchmair, R., Mahata, S.K., Mahata, M., Fischer-Colbrie, R., Hogue-Angeletti, R., Saria, A., and Winkler, H., 1993, Distribution of secretoneurin, a peptide derived from secretogranin II, in rat brain: an immunocytochemical and radioimmunological study. Neuroscience 54: 923–944.
Miller, C., Kirchmair, R., Troger, J., Saria, A., Fleischhacker, W. W., Fischer-Colbrie, R., Benzer, A., and Winkler, H., 1996, CSF of neuroleptic-naive first-episode schizophrenic patients: levels of biogenic amines, substance P, and peptides derived from chromogranin A (GE-25) and secretogranin II (secretoneurin). Biol. Psych. 39: 911–918.
Oulyadi, H., Davoust, D., and Vaudry, H., 1997, A determination of the solution conformation of secretoneurin, a neuropeptide originating from the processing of secretogranin II, by IH-NMR and restrained molecular dynamics. Eur. J. Biochem. 246: 665–673.
Prommegger, R., Obrist, P., Ensinger, C., Schwelberger, H.G., Wolf, C., Fischer-Colbrie, R., Mikuz, G., and Bodner, E., 1998, Secretoneurin in carcinoids of the appendix-immunohistochemical comparison with chromogranins A, B and secretogranin II. Anticancer Res. 18: 3999–4002.
Reinisch, N., Kirchmair, R., Kiihler, C.M., Hogue-Angeletti, R., Fischer-Colbrie, R., Winkler, H., and Wiedermann, C.J., 1993, Attraction of human monocytes by the neuropeptide secretoneurin. FEBS Lett. 334: 41–44.
Saria, A., Troger, J., Kirchmair, R., Fischer-Colbrie, R., Hogue-Angeletti, R., and Winkler, H., 1993, Secretoneurin releases dopamine from rat striatal slices: a biological effect of a peptide derived from secretogranin II (chromogranin C). Neuroscience 54: 1–4.
Scammell, J.G., Sumners, C., Reutter, M.A., Valentine, D.L., and Jones, L.C., 1995, Regulation of secretogranin II mRNA in rat neuronal cultures. Mol. Brain Res. 33: 326–332.
Schneitler, C., Kiihler, C., Wiedermann, C.J., Hogue-Angeletti, R., and Fischer-Colbrie, R., 1998, Specific binding of a 125I-secretoneurin analogue to a human monocytic cell line. J. Neuroimmunol. 86: 87–91.
Schratzberger, P., Reinisch, N., Kiihler, C.M., and Wiedermann, C.J., 1996a, Deactivation of chemotaxis of human neutrophils by priming with secretogranin 11-derived secretoneurin. Regul. Pept. 63: 65–71.
Schratzberger, P., Reinisch, N., Prodinger, W.M., Kiihler, C.M., Sitte, B.A., Bellmann, R., Fischer-Colbrie, R., Winkler, H., and Wiedermann, C.J., 1997, Differential chemotactic activities of sensory neuropeptides for human peripheral blood mononuclear cells. J. Immunol. 158: 3895–3901.
Schratzberger, P., Wöll, E., Reinisch, N., Kiihler, C.M., and Wiedermann, C.J., 1996b, Secretoneurin-induced in vitro chemotaxis of human monocytes is inhibited by pertussis toxin and an inhibitor of protein kinase C. Neurosci. Lett. 214: 208–210.
Schurmann, G., Bishop, A.E., Facer, P., Eder, U., Fischer-Colbrie, R., Winkler, H., and Polak, J.M., 1995, Secretoneurin: a new peptide in the human enteric nervous system. Histochem. Cell Biol. 104: 11–19.
Seidah, N.G., Day, R., and Chrétien, M., 1993, The family of pro-hormone and pro-protein wnvertases. Biochem. Soc. Trans. 21: 685–691.
Shen, P.J., and Gundlach, A.L., 1998, Differential increases in chromogranins, but not synapsin I, in cortical neurons following spreading depression: Implications for functional roles and transmitter peptide release. Eur. J. Neurosci. 10: 2217–2230.
Simon, J.P., and Aunis, D., 1989, Biochemistry of the chromogranin A protein family. Biochem. J. 262: 1–13.
Storch, M.K., Fischer-Colbrie, R., Smith, T., Rinner, W.A., Hickey, W.F., Cuzner, M.L., Winkler, H., and Lassmann, H., 1996, Co-localization of secretoneurin immunoreactivity and macrophage infiltration in the lesions of experimental autoimmune encephalomyelitis. Neuroscience 71: 885–893.
Tötsch, M., Kunk, B., Dockhorn-Dwominak, B., Ofner, D., Fischer-Colbrie, R., Mikuz, G., Böcker, W., and Schmid, K.W., 1994, Immunohistochemical demonstration of chromogranin A, chromogranin B, and secretoneurin in primary non-small-cell carcinomas of the lung. Endocr. Pathol. 5: 212–217.
Vaudry, H., and Conlon, J.M., 1991, Identification of a peptide arising from the specific posttranslation processing ofsecretogranin II. FEBS Lett. 284: 31–33.
Winkler, H., and Fischer-Colbrie, R., 1992, The chromogranins A and B: the first 25 years and future perspectives. Neuroscience 49: 497–528.
You, Z.B., Saria, A., Fischer-Colbrie, R., Terenius, L., Goiny, M., and Herrera-Marschitz, M., 1996, Effects of secretogranin II-derived peptides on the release of neurotransmitters monitored in the basal ganglia of the rat with in vivo microdialysis. Naunyn-Schmied. Arch. Pharmacol. 354: 717–724.
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Kähler, C.M., Fischer-Colbrie, R. (2002). Secretoneurin — A Novel Link Between The Nervous and the Immune System. In: Helle, K.B., Aunis, D. (eds) Chromogranins. Advances in Experimental Medicine and Biology, vol 482. Springer, Boston, MA. https://doi.org/10.1007/0-306-46837-9_22
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