This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Acker, H., and Xue, D., 1995, Mechanisms of O2 sensing in the carotid body in comparison with other O2-sensing cells. News Physiol. Sci. 10:211–215.
Almaraz, L., Gonzalez., C., and Obeso, A., 1986, Effects of high potassium on the release of [3H]dopamine from the cat carotid body in vitro. J. Physiol. (Lond) 379: 293–307.
Buckler, K., 1999, Backgroundleak K+-currents and oxygen sensing in carotid body type I cells. Respir. Physiol. 115:179–187.
Bunn, H.F., and Poyton, R. O., 1996, Oxygen sensing and molecular adaptation to hypoxia. Phsiol. Rev. 76: 839–885.
Cross, A.R., Henderson, L., Jones, O.T.G., Delpiano, M.A, Hentschel, J., Acker, H., 1990, Involvement on an NAD(P)H oxidase as a PO2 sensor protein in the rat carotid body. Biochem. J. 272: 743–747
Gonzalez, C., 1998, Sensitivity to physiologic hypoxia In: Oxygen regulation of ion channels and gene expression. (J. Lopez.-Barneo and E.K. Weir, eds), Futura Publishing Co. Inc. Armonk. N.Y., pp. 321–336.
Gonzalez, C., Almaray., L., Obeso, A., and Rigual, R., 1992, Oxygen and acid chemoreception in the carotid body chemoreceptors. Trends Neurosci 15: 146–153.
Gonzalez, C., Almaraz, L., Obeso, A., and Rigual, R., 1994, Carotid body chemoreceptors: from natural stimuli to sensory discharges. Physiol. Rev. 74:829–898.
Gonzalez, C., Lopez-Lopez, J.R., Obeso, A., Perez-Garcia, M.T., and Rocher, A., 1995, Cellular mechanisms of oxygen chcmoreception in the carotid body. Physiol. 102:137–147.
Gonzalex., C., Lopez.-Lopez, J.R., Obeso, A., Rocher, A., and Garcia-Sancho, J., 1993, Ca+-dynamics in chemoreceptor cells: an overview. Adv. Exp. Med. Biol. 337: 149–156.
Haddad, G.G., and Jrang, C., 1997, O2-scnsing mechanisms in excitable cells: role of plasma membrane K+ channels. Annu Rev Physiol. 59:23–42.
Halliwell, B., 1988, Oxygen redical sand tissue injury. Proceedings of an Upjohn Symposium Amer. Physiol. Soc., Bethesda, Maryland, USA.
Halliwell, B., and Gutteridge, M.C., 1999, Free Radicals in Medicine and Biology (3rd Edition) Oxford University Press, Oxford, U.K.
Höhler, B., Goldenberg, A., Lange, B., Möllcr, W., Tschöpe, M., and Kummer, W., 1999, Reactive oxygen species and their involvement in hypoxia regulated gene transcription in PC12cells. Physiol. Res 48:S78.
Kojima, S., Nomura, T., Icho, T., Kajiwara, Y., Kitabatake, K., and Kubota, K., 1993, Inhibitor effect of neopterin on NADPH-dependent superoxidc-generatingoxidase of rat peritoneal macrophagcs. FEBS Lett. 329: 125–128.
Lander, H.M., 1997, An essential role for free radicals and derived species in signal transduction. FASEB J. 11: 118–124.
Le Cabec V., and Marindonneau-Parini, I., 1995, Complete and reversible inhibition of NADPH oxidase in human neutrophils by phenylarsine oxide at a step distal to membrane translocations of the enzyme subunits. J Biol. Chem. 270:2067–2073.
Lopez-Lopez, J.R., Peers, C., 1997, Electrical properties of chemoreceptor cells. In: The Carotid Body Chemoreceptors (C. Gonzalez, ed.). Springer-Verlag, Heidelberg, Germany, pp. 65–77.
Nakamura, H., Nakamura, K., and Yodoi, J., 1997, Redox regulation of cellular activation. Annu. Rev. Immunol. 15:351–69
Obeso, A., Gomez-Niño, A., and Gonzalez, C., 1999, NADPH oxidase inhibition docs not interfere with low PO2 transduction in rat and rabbit CB chemoreceptor cells. Am. J. Physiol. 276:C593–C601.
Obeso, A., Gonzalez, C., Rigual, R., Dinger, B., and Fidone, S., 1993, Effect of low O2 on glucose uptake in rabbit carotid body. J. Appl. Physiol. 74: 2387–2393.
Obeso, A., Rocher, A., Fidone, S., and Gonzalez, C., 1992, The role of dihydropyridine-sensitive Ca2+ channels in stimulus-evoked catecholamine release from chemoreceptor cells of the carotid body. Neuroscience 47: 463–472.
Obeso, A., Rocher, A., Herreros, B., and Gonzalez, C., 1997, Oxygen consumption and energy metabolism in the carotid body. In: The Carotid Body Chemoreceptors (C. Gonzalez, ed.). Springer-Verlag, Heidelberg, Germany, pp. 31–45.
Perez-Garcia, M.T., Lopez-Lopez, J.R., and Gonzalez, C., 1999, KvBl 2subunit coexpression in HFK293 cells confers O2 sensitivity to Kv4.2 but not to shaker channels. J. Gen. Physiol 113:897–907.
Punchard, N.A. and Kelly, F.J., 1996, Free Radicals. A practical approach. IRL Press-Oxford University Press. Oxford, UK, pp. 1–8.
Reeves, J.T., Wagner, W.W., McMurtry, I.F., and Grover, R.F., 1979, Physiological effects of high altitude on the pulmonary circulation. In: Environmental Physiology III, edited by A.C. Guyton University Park Press, pp. 253–289.
Thuringer, D. and Findlay, I., 1997, Contrasting effects of intracellular redox couples on the regulation of maxi-K+ channels in isolated myocytes from rabbit pulmonary artery. J. Physiol. 500: 583–592.
Yarowsky, P., and Ingvar, O.H., 1981, Neuronal activity and energy metabolism. Fed. Proc. 40: 2353–2362.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2002 Kluwer Academic Publishers
About this chapter
Cite this chapter
Obeso, A., Sanz-Alfayate, G., Agapito, M.T., Gonzalez, C. (2002). Significance of Ros in Oxygen Chemoreception in the Carotid Body Chemoreception. In: Lahiri, S., Prabhakar, N.R., Forster, R.E. (eds) Oxygen Sensing. Advances in Experimental Medicine and Biology, vol 475. Springer, Boston, MA. https://doi.org/10.1007/0-306-46825-5_41
Download citation
DOI: https://doi.org/10.1007/0-306-46825-5_41
Publisher Name: Springer, Boston, MA
Print ISBN: 978-0-306-46367-9
Online ISBN: 978-0-306-46825-4
eBook Packages: Springer Book Archive