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Oxygen Sensing pp 405–410Cite as

Effect of Adenosine on CO2 Chemosensitivity

Functional, cellular and molecular studies

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Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 475))

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References

  • Buckler, K. J. (1997). A novel oxygon-sensitive potassium current in rat carotid body type 1 cells. Journal Of Physiology 498, 649–662.

    CAS  PubMed  Google Scholar 

  • Chen,.J., Dinger, B. & Fidone, S. J. (1997). cAMP production in rabbit carotid body: Role of adenosine. Journal Of Applied Physiology 82, 1771–1775.

    CAS  PubMed  Google Scholar 

  • Delpiano, M. A. & Acker, H. (1991). Hypoxia increases the cyclic-AMP content of the cat carotid-body in vitro. Journal Of Neurochemistry 57, 291–297.

    CAS  PubMed  Google Scholar 

  • Eden, G J. & Hanson, M. A. (1987). Maturation of the respiratory response to acute hypoxia in the newborn rat. Journal of Physiology 392, 1–9.

    CAS  PubMed  Google Scholar 

  • Fitzgerald, R. S. & Parks, D. C. (1971). Effect of hypoxia on carotid chemoreceptor response to carbon dioxide in cats. Respiration Physiology 12, 218–229.

    Article  CAS  PubMed  Google Scholar 

  • KaelinLang, A., Lauterburg, T. & Burgunder, J. M. (1998). Expression of adenosine A2a receptor gene in rat dorsal root and autonomic ganglia. Neuroscience Letters 246, 21–24.

    CAS  Google Scholar 

  • Lahiri, S. & DeLaney, R. G. (1975). Stimulus interaction in the responses of carotid body chemoreceptor single afferent fibers. Respiration Physiology 24, 249–266.

    CAS  PubMed  Google Scholar 

  • McQueen, D. S. & Ribeiro, J. A. (1981). Effect of adenosine on carotid chemoreceptor activity in the cat. British Journal Of Pharmacology 74, 129–136.

    CAS  PubMed  Google Scholar 

  • McQueen, D. S. & Ribeiro, J. A. (1986). Pharmacological characterisation of the receptor involved inchemoexitation induced by adenosine. British Journal of Pharmacology 88, 615–620.

    CAS  PubMed  Google Scholar 

  • Monteiro, K. C.. Vera-Cruz, P. & Silva e Sousa, M. A. (1996). Adenosine increases the cAMP content of the rat carotid body in vitro. Advances in Experimental Medicine and Biology 410, 299–303.

    CAS  PubMed  Google Scholar 

  • Pepper, D. R., Landauer, R. C. & Kumar, P. (1995). Postnataldevelopment of CO2-O2 interaction in the rat carotid body in vitro. Journal of Physiology 485, 531–541.

    CAS  PubMed  Google Scholar 

  • Perez-Garcia, M. T., Almaraz, L. & Gonzalez, C. (1990). Effects ofdifferenttypes of stimulation on cyclic-AMP content in the rabbit carotid body: functional significance. Journal of Neurochemislry 55, 1287–1293.

    CAS  Google Scholar 

  • Perez-Garcia, M. T., Almaraz., L. & Gonzalez, C. (1991). Cyclic-amp modulates differentially the release of dopamine induced by hypoxia and other stimuli and increases dopaminc synthesis in the rabbit carotid-body. Journal Of Neurochemistry 57, 1992–2000.

    CAS  PubMed  Google Scholar 

  • Read, D. J. C. (1967). Aclinical method for assessing the ventilatory response to carbon dioxide. Australasian Annals of Medicine 16, 20–32.

    CAS  PubMed  Google Scholar 

  • Roy, A., Rozanov, C.,, R.,, I., Mokashi, A. & Lahiri, S. (1997). Acid-sensing by carotid body is inhibitied by blockers of voltage-sensitive Ca2+ channels. Brain Research 769, 396–399.

    Article  CAS  PubMed  Google Scholar 

  • Runold, M., Chermack, N. S. & Prabhakar, N. R. (1990). Effect of adenosine on isolated and superfused cat carotid-body activity. Neuroscience Letters 113, 111–114.

    Article  CAS  PubMed  Google Scholar 

  • Sebastiao, A. M. & Ribeiro, J. A. (1996). Adenosine A2 receptor-mediated excitatory actions on the nervous system. Progress in Neurobiology 48, 167–189.

    Article  CAS  PubMed  Google Scholar 

  • Shirahata, M. & Fitzgerald, R. S. (1991). Dependency of hypoxic chemotransduction in cat carotid-body onvoltage-gated calcium channels. Journal Of Applied Physiology 71, 1062–1069.

    CAS  PubMed  Google Scholar 

  • Vandier, C., Conway, A. F., Landauer, R. C. & Kumar, P. (1999). Presynaptic action of adenosine on a 4-aminopyridine sensitive current in the rat carotid body. Journal of Physiology 515, 419–429.

    Article  CAS  PubMed  Google Scholar 

  • Wang, W. J., Cheng, G. F., Dinger, B. G. & Fidone, S. J. (1989). Effects of hypoxia on cyclic-nucleotide formation in rabbit carotid-body invitro. Neuroscience Letters 105, 164–168.

    Article  CAS  PubMed  Google Scholar 

  • Wang, W. J., Cheng, G. F., Yoshizaki, K., Dinger, B. & Fidone, S. (1991). The role of cyclic-AMP in chemoreception in the rabbit carotid-body. Brain Research 540, 96–104.

    Article  CAS  PubMed  Google Scholar 

  • Weaver, D. R. (1993). A2a adenosine receptor gene expression in developing rat brain. Molecular Brain Research 20, 313–327.

    Article  CAS  PubMed  Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Physiology, The Medical School, University of Birmingham, Birmingham, B15 2TT, UK

    P. Kumar, A. F. Conway, C. Vandier, N. J. Marshall & J. Bruynseels

  2. Department of Surgery, The Medical School, University of Birmingham, Birmingham, B15 2TT, UK

    G. M. Matthews

Authors
  1. P. Kumar
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  2. A. F. Conway
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  3. C. Vandier
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  4. N. J. Marshall
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  5. J. Bruynseels
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  6. G. M. Matthews
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Editor information

Editors and Affiliations

  1. University of Pennsylvania Medical Center, Philadelphia, Pennsylvania

    Sukhamay Lahiri  & Robert E. Forster II  & 

  2. Case Western Reserve University, Cleveland, Ohio

    Naduri R. Prabhakar

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© 2002 Kluwer Academic Publishers

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Kumar, P., Conway, A.F., Vandier, C., Marshall, N.J., Bruynseels, J., Matthews, G.M. (2002). Effect of Adenosine on CO2 Chemosensitivity. In: Lahiri, S., Prabhakar, N.R., Forster, R.E. (eds) Oxygen Sensing. Advances in Experimental Medicine and Biology, vol 475. Springer, Boston, MA. https://doi.org/10.1007/0-306-46825-5_38

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  • DOI: https://doi.org/10.1007/0-306-46825-5_38

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-0-306-46367-9

  • Online ISBN: 978-0-306-46825-4

  • eBook Packages: Springer Book Archive

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