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Hodis, H.N., Mack, W.J., Azen, S.P., Alaupovic, P., Pogoda, J.M., LaBree, L., Hemphill, L.C., Kramsch, D.M. & Blankenhorn, D.H. 1994. Circulation 90:42–49. Triglyceride-and cholesterol-rich lipoproteins have a differential effect on mild/moderate and severe lesion progression as assessed by quantitative coronary angiography in a controlled trial of lovastatin.
Staels, B., Vu-Dac, N., Kosykh, V.A., Saladin, R., Fruchart, J.C., Dallongeville, J. & Auwerx, J. 1995. J. Clin. Invest. 95:705–712. Fibrates downregulate apolipoprotein C-III expression independent of induction of peroxisomal acyl coenzyme A oxidase. A potential mechanism for the hypolipidemic induction action of fibrates.
Kinsella, J.E., Lokesh, B. & Stone, R.A. 1990. Am. J. Clin. Nutr. 52:1–28. Dietary n-3 polyunsaturated fatty acids and amelioration of cardiovascular disease: possible mechanisms.
Bonaa, K.H., Bjerve, K.S., Straume, B., Gram, I.T. & Thelle, D. 1990. N Engl. J. Med. 322:795–801. Effect of eicosapentaenoic and docosahexaenoic acids on blood pressure in hypertension. A population-based intervention trial from the Tromso study.
Leaf, A. & Weber, P.C. 1988. AC Engl. J. Med. 318:549–557. Cardiovascular effects of n-3 fatty acids.
Skorve, J. & Berge, R.K. 1993. Biochim. Biophys. Acta 1167:175–181. The hypocholesteremic effect of sulfur-substituted fatty acid analogues in rats fed a high carbohydrate diet.
Skorve, J., Asiedu, D., Rustan, A.C., Drevon, C.A., Al-Shurbaji, A., Berge, R.K. 1990. J. Lipid. Res. 31:1627–1635. Regulation of fatty acid oxidation and triglyceride and phospholipid metabolism by hypolipidemic sulfur-substituted fatty acid analogues.
Bell, R.M., Coleman, R.M. 1980. Ann. Rev. Biochem. 49:459–487. Enzymes of glycerolipid synthesis in eucaryotes.
Rustan, A.C., Nossen, J.O., Christiansen, E.N. & Drevon, C.A. 1988. J. Lipid Res. 29:1417–1426. Eicosapentaenoic acid reduces hepatic synthesis and secretion of triacylglycerol by decreasing the activity of acyl-coenzyme A: 1,2-diacylglycerol acyltransferase.
Skorve, J., Rustan, A.C. & Berge, R.K. 1995. Lipids 30:987–994. Effects of non-beta-oxidizable sulfursubstituted fatty acid analogues on synthesis and secretion of triacylglycerol and cholesterol in cultured rat hepatocytes.
Aarsland, A., Berge, R.K., Bremer, J. & Aarsæther, N. 1990. Biochim. Biophys. Acta 1033:176–183. The hypolipidemic peroxisome-proliferating drug, bis(carboxymethylthio)-1.10 decane, a dicarboxylic metabolite of tiadenol, is activated to an acylenzyme A thioester.
Arsland, A., Lundquist, M, Borretsen, B. & Berge, R.K. 1990. Lipids 25:546–548. On the effect of peroxisomal β-oxidation and carnitine palmitoyltransferase activity by eicosapentaenoic acid in liver and heart from rats.
Wong, S.H., Nestel, P.J., Trimble, R.P., Stores, G.B., Illman, R.J. & Topping, D.L 1984. Biochim. Biophys. Acta 792:103–109. The adaptive effects of dietary fish and safflower oil on lipid and lipoprotein metabolism in perfused rat liver.
Skrede, S. & Bremer, J. 1993. Biochim. Biophys. Acta 1167:189–196. Acylcarnitine formation and fatty acid oxidation in hepatocytes from rats treated with tetradecylthioacetic acid (a 3-thia fatty acid).
Asiedu, D.K., Demoz, A., Skorve, J., Grav, H.J., Berge, R.K. 1994. Biochem. Pharmacol. 49:1013–1022. Acute modulation of rat hepatic lipid metabolism by sulphur-substituted fatty acids analogues.
Skorve, J., Ruyter, B., Rustan, A.C., Christiansen, E.N., Drevon, C.A. & Berge, R.K. 1990. Biochem. Pharmacol. 40:2005–2012. Effect of 3-and 4-thia-substituted fatty acids on glycerolipid metabolism and mitochondrial β-oxidation in rat liver.
Verhoeven, N.M., Roe, D.S., Kok, R.M., Wanders, R.J., Jakobs, C. & Roe, C.R. 1998. J. Lipid. Res. 39:66–74. Phytanic acid and pristanic acid are oxidized by sequential peroxisomal and mitochondrial reactions in cultured fibroblasts.
Skorve, J., Al-Shurbaji, A., Asiedu, D., Björkhem, I., Berglund, L., Berge, R.K. 1993. J. Lipid Res. 34:1177–1185. On the mechanism of the hypolipidemic effect of sulfur-substituted hexadecanedoic acid (3-thiadicarboxylic acid) in normolipidemic rats.
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Berge, R.K., Madsen, L., Vaagenes, H. (2002). Hypolipidemic 3-Thia Fatty Acids. In: Quant, P.A., Eaton, S. (eds) Current Views of Fatty Acid Oxidation and Ketogenesis. Advances in Experimental Medicine and Biology, vol 466. Springer, Boston, MA. https://doi.org/10.1007/0-306-46818-2_14
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DOI: https://doi.org/10.1007/0-306-46818-2_14
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