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Effects of Melatonin and its Relation to the Hypothalamic-Hypophyseal-Gonadal Axis

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Melatonin After Four Decades

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References

  1. Bartness, T.J., Powers, J.B., Hastings, M.H., Bittman, E.L., and Goldman, B.D. The timed infusion paradigm for melatonin delivery: what has it taught us about the melatonin signal, its reception, and the photoperiodic control of seasonal responses?. J. Pineal. Res. 15:161–190, 1993.

    PubMed  CAS  Google Scholar 

  2. Colmenero, M.D., Diaz, B., Miguel, J.L., Gonzales, M.L., Esquifino, A., and Marin, B. Melatonin administration during pregnancy retards sexual maturation of female offspring in the rat, J. Pineal Res., 11:23–27, 1991.

    PubMed  CAS  Google Scholar 

  3. Damian, E., Ianaş O., Badescu, I., and Oprescu, M., Gonadotropin Inhibiting Activity of Melatonin-free Pineal Extract, Advances Biosciences. 29:171–175, 1980

    Google Scholar 

  4. Diaz-Lopez, B., Colmenero, M.D., Diaz-Rodriguez, M.E., Arce, Fraguas A., Esquifino, Parras, A., Marin, and Fernandez B. Effect of pinealectomy and melatonin treatment during pregnancy on the sexual development of the female and male rat offspring. Eur. J. Endocrinol. 132:765–770,1995

    PubMed  CAS  Google Scholar 

  5. Esquifino, A.I., Arce, A., Villanua, M.A., and Cardinali, D.P. Tiventy-four hour rhythms of serum prolactin, growth hormone and luteinizing hormone levels, and of medial basal hypothalamic corticotropin-releasing hormone levels and dopamine and serotonin metabolism in rats neonatally administered melatonin. J. Pineal Res. 22:52–58, 1997.

    PubMed  CAS  Google Scholar 

  6. Grosse, J., Maywood, E.S., Ebling, F.J.P., and Hastings, M.H. Testicular regression in pinealectomized Syrian hamsters following infusion of melatonin delivered on non-circadian schedules. Biol. Reprod. 49:666–674, 1993.

    Article  PubMed  CAS  Google Scholar 

  7. Hattori, A., Herbert, D.C., Vaughan, M.K., Yaga, K., and Reiter, R.J. Melatonin inhibits luteinizing hormone releasing hormone (LHRH) induction of LH release from fetal rat pituitary cells. Neurosci. Lett. 184:109–112, 1995.

    Article  PubMed  CAS  Google Scholar 

  8. Irvine, D.S. Epidemiology and aetiology of male infertility. Hum. Reprod. 13:33–44, 1998

    PubMed  Google Scholar 

  9. Langu, U. Melatonin, and Puberty. Pin. Res. Rev. 4:199–254, 1986.

    Google Scholar 

  10. Luboshitzky, R., Wagner, O., Lavi, S., Herer, P., and Lavie P. Abnormal melatonin secretion in hypogonadal men: the effect of testosterone treatment. Clinical Endocrinology. 47:463–469, 1997.

    Article  PubMed  CAS  Google Scholar 

  11. Malpaux B., Daveau, A., Maurice-Mandon, F., Duarte, G., and Chemineau, P Evidence that melatonin acts in the premammillary hypothalamic area to control reproduction in the ewe: Presence of binding sites and stimulation of luteinizing hormone secretion by in situ microimplant delivery. Endocrinology. 139:1508–1516, 1998.

    Article  PubMed  CAS  Google Scholar 

  12. Neašu, E., Simionescu, L., Zimel, A., and Caragheorgheopol, A. The development of a radioim-munoassay system for testosterone and dihydrotestosterone. Rev. Roum. Méd-Endocrinol. 28:127–132, 1990.

    Google Scholar 

  13. Okatani, Y., Watanabe, K., Morioka, N., Hayashi, K., and Sagara, Y. Nocturnal changes in pineal melatonin synthesis during puberty: relation to estrogen and progesterone levels in female rats. J. Pineal Res. 22:33–41, 1997

    PubMed  CAS  Google Scholar 

  14. Petterborg, L.J. Photoperiod, pineal, and reproduction in the white-footed mouse. Advan. Pin. Res. 1:177–183, 1986.

    CAS  Google Scholar 

  15. Pitrosky, B., Kirsch, R., Vivien-Roels, B., Georg-.Bentz, I., Canguilhem, B., and Pevet, P. The photoperiodic response in Syrian hamster depends upon a melatonin-driven circadian rhythm of sensitivity to melatonin. J. Neuroendocr. 7:889–895, 1995.

    Article  CAS  Google Scholar 

  16. Reiter, J.R. The pineal, and its hormones in the control of reproduction in mammals. Endocrine Reviews. 1:109–131, 1980.

    Article  PubMed  CAS  Google Scholar 

  17. Reiter, R.J. Melatonin, and human reproduction. Ann. Med. 30:103–108, 1998.

    PubMed  CAS  Google Scholar 

  18. Tamarkin, L., Baird, C.J., and Almeuda, O.F.X. Melatonin: a coordinating signal for mammalian reproduction? Science. 227:714–720, 1985.

    PubMed  CAS  Google Scholar 

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Ianaş, O., Manda, D., Câmpean, D., Ionescu, M., Soare, G. (2002). Effects of Melatonin and its Relation to the Hypothalamic-Hypophyseal-Gonadal Axis. In: Olcese, J. (eds) Melatonin After Four Decades. Advances in Experimental Medicine and Biology, vol 460. Springer, Boston, MA. https://doi.org/10.1007/0-306-46814-X_35

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  • DOI: https://doi.org/10.1007/0-306-46814-X_35

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-0-306-46134-7

  • Online ISBN: 978-0-306-46814-8

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