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References
Adam, M., Delsanti, M., and Jannink, G., 1976, Light scattering by cooperative diffusion in semi-dilute polymer solutions, J. Phys, Lett. 37:153–156.
am Ende, M. T., 1993, Transport and Interaction of Ionizable Drugs and Proteins in Hydrophilic Polymers. Ph.D. Thesis, Purdue University.
Amis, E. J., Janmey, P. A., Ferry, J. D., and Yu, J., 1983, Quasi-elastic light scattering of gelatin solutions and gels, Macromolecules 16:441–446.
Arteaga, C. L., Hurd, S. D., Dugger, R. C., Winnier, A. R., and Robertson, J. B., 1994, Epidermal growth factor receptors in human breast carcinoma cells: A potential selective target for transforming growth factor a-Pseudomonas exotoxin 40 fusion protein, Cancer Res. 54:703–4709.
Baker, R., 1987, Controlled Release of Biologically Active Agents, John Wiley & Sons, New York.
Berens, A. R., and Hofenberg, H. B., 1978, Diffusion and relaxation in glassy polymer powders: 2. Separation of diffusion and relaxation parameters, Polymer 19:490–496.
Braatz, J. A., Heifetz, A. H., and Kehr, C. L., 1992, A new hydrophilic polymer for biomaterial coatings with low protein adsorption. J. Biomater. Sci. Polym Ed 3(6):451–462.
Brondsted, H., and Kopecek, J., 1991, Hydrogels for site-specific oral drug delivery: Synthesis and characterization Biomaterials 12:584–592.
Bueche, F., 1962, Physical Properties of Polymers, Interscience Publishers, New York.
Caliceti, P., Veronese, F., Schiavon, O., Lora, S., and Carenza, M., 1992, Controlled release of proteins and peptides from hydrogels synthesized by gamma ray-induced polymerization, II Farmaco 47(3):275–286.
Canal, T., and Peppas, N. A., 1989, Correlation between mesh size and equilibrium degree of swelling of polymeric networks, J. Biomed Mater. Res. 23:1183–1193.
Carelli, V., Di Colo, G., Nannipieri, E., and Serafini, M.F., 1989, Evaluation of solution impregnation method for loading drugs into suspension-type polymer matrices: A study of factors determining the patterns of solid drug distribution in matrix and drug release from matrix, Int. J. Pharm. 55:199–207.
Colton, C. K., Smith, K. A., Merrill, E. W., and Farrell, P. C., 1971, Permeability studies with cellulosic membranes, J. Biomed. Mater. Res. 5:459–488.
Crank, J., 1975, The Mathematics of Diffusion, Academic Press, New York.
Crank, J., and Park, G. S., 1968, Diffusion in Polymers, Academic Press, New York.
de Gennes, P. G., 1979, Scaling Concepts in Polymer Physics, Cornell University Press, Ithaca, New York.
Dillman, W. J., Jr., and Miller, I. F., 1973, On the adsorption of serum proteins on polymer membrane surfaces, J. Cotloid. Interface Sci. 44:221–241.
Domb, A., Davidson, G. W. R., III, and Sanders, L. M., 1990, Diffusion of peptides through hydrogel membranes, J. Controlled Release 14:133–144.
Dong, L. C., and Hoffman, A. S., 1991, A novel approach for preparation of pH sensitive hydrogels for enteric drug delivery, J. Controlled Release 15:141–152.
Greenley, R. Z., Brown, R. M., Garbow, J., Vogt, C. E., Zia, H., Rodgers, R. L., Christie, M., and Luzzi, L. A., 1990, Polymer matrices for oral delivery Polym. Prep. (Am. Chem. Soc., Div. Polym. Chem.) 31(2):182–183.
Hayashi, Y., Yoshioka, S., Aso, Y., Po, A. L. W., and Terao, T., 1994, Entrapment of proteins in poly(L-lactide) microspheres using reversed micelle solvent evaporation Pharm.Res. 11(2):337–340.
Heller, J., 1988, Chemically self-regulated drug delivery systems, J. Controlled Release 8:111–125.
Ho, N. F. H., Ganesan, M. G., Weiner, N. D., and Flynn, G. L., 1986, Mechanisms of topical delivery of liposomally entrapped drugs, in: Advances in Drug Delivery Systems (J. M. Anderson and S. W. Kim, eds.), Controlled Release Series No. 1, Elsevier, New York, pp. 61–65.
Horbett, T. A., 1982, Protein adsorption on biomaterials, in: Biomaterials: Interfacial Phenomena and Applications (S. L. Cooper, N. A. Peppas, A. S. Hoffman, and B. D. Ratner, eds.), Advances in Chemistry Series No. 199, American Chemical Society, Washington, D.C., pp. 233–244.
Hsieh, D. S. T., Rhine, W. D., and Langer, R., 1983, Zero-order controlled release polymer matrices for micro-and macromolecules, J. Pharm. Sci.. 72(1):17–22.
Jabbari, E., Wisniewski, N., and Peppas, N. A., 1993, Evidence of mucoadhesion by chain interpenetration at a poly(acrylic acid)/mucin interface using ATR-FTIR spectroscopy, J. ControlledRelease 26:99–108.
Jeffery, H., Davis, S. S., and O’Hagen, D. T., 1993, The preparation and characterization of poly(lactide-co-glycolide) microparticles. II. The entrapment of a model protein using a (water-in-oil)-in-water emulsion solvent evaporation technique, Pharm. Res. 10:362–368.
Kim, C. J., and Lee, P. I., 1991, Swelling-controlled drug release from anionic polyelectrolyte gel beads, Proc. Int. Symp. Control. Rel. Bioact. Mater. 18:451–452.
Kopecek, J., Kopeckova, P., Brondsted, H., Rathi, R., Rihova, B., Yen, P.-Y., and Ikesue, K., 1992, Polymers for colon-specific drug delivery, J. Controlled Release 19:121–130.
Korsmeyer, R. W., 1991, Diffusion controlled systems: Hydrogels, in: Polymers for Controlled Drug Delivery (P. J. Tarcha, ed.), CRC Press, Boca Raton, Florida, pp. 15–37.
Langer, R., 1990, New methods of drug delivery, Science 249:1527–1533.
Langer, R., and Folkman, J., 1976, Polymers for the sustained release of proteins and other macromolecules, Nature 263:797–800.
Langer, R., and Peppas, N., 1983, Chemical and physical structure of polymers as carriers for controlled release of bioactive agents: A review, J. Mater. Sci.: Rev. Macromol. Chem. Phys. C23(1):61–126.
Lee, P. I., 1988, Synthetic hydrogels for drug delivery: Preparation, characterization, and release kinetics, in: Controlled Release Systems: Fabrication Technology, Vol. II (D. S. T. Hsieh, ed.), CRC Press, Boca Raton, Florida, pp. 61–82.
Lee, V. H. L., 1992, Peptide and Protein Drug Delivery, Marcel Dekker, New York.
McGee, J. P., Davis, S. S., and O’Hagan, D. T., 1995, Zero order release of protein from poly(D,L-lactide-co-glycolide) microparticles prepared using a modified phase separation technique, J. Controlled Release 34:17–86.
McNeill, M. E., and Graham, N. B., 1993, Properties controlling the diffusion and release of water-soluble solutes from poly(ethylene oxide) hydrogels 1. Polymer composition, J. Biomater. Sci Polym. Ed. 4:305–322.
Munch, J. P., Candau, S., Duplexxis, R., Picot, C., Herz, J., and Benoit, H., 1976, Spectrum of light scattered from viscoelastic gels, J. Polym. Sci.: Polym. Phys. Ed. 14:1097–1109.
Park, K., 1988, Enzyme-digestible swelling hydrogels as platforms for long-term oral drug delivery: Synthesis and characterization, Biomaterials 9:435–441.
Patterson, G. D., 1981, Light scattering from concentrated polymer solutions and gels, Polym. Prepr. Am. Chem. Soc., Div. Polym. Chem. 22:709–713.
Peppas, N. A., and Lustig, S. R., 1985, The role of cross-links, entanglements, and relaxations of macromolecular carriers in the diffusional release of biologically active materials: Conceptual and scaling relationships, Ann. N. Y. Acad Sci. 446:26–41.
Peppas, N. A., and Meadows, D. L., 1983, Macromolecular structure and solute diffusion in membranes: An overview of recent theories, J. Membr. Sci. 16361–377.
Peschier, L. J. C., Bouwstra, J. A., de Bleyser, J., Junginger, H. E., and Leyte, J. C., 1993, Water mobility and structure in poly[2-hydroxyethylmethacrylate] hydrogels by means of the pulsed field gradient NMR technique, Biomaterials 14:945–952.
Price, F. P., Gilmore, P. T., Thomas, E. L., and Laurence, R. L., 1978, Polymer/polymer diffusion, J. Polym. Sci.: Polym. Symp. 63:33–44.
Rabek, J. F., 1980, Experimental Methods in Polymer Chemistry: Physical Principles and Applications, John Wiley & Sons, New York.
Ritger, P. L., and Peppas, N. A., 1987, A simple equation for description of solute release I. Fickian and non-Fickian release from non-swellable devices in the form of slabs, spheres, cylinders, or discs, J. Controlled Release 5:23–36.
Roorda, W., 1994, Do hydrogels contain different classes of water?, J. Biomater. Sci. Polym. Ed. 5:383–395.
Sahlin, J. J., 1992, Polymer Chain Interdiffusion in Gel/Gel Adhesion, Ph.D. thesis, Purdue University.
Sato, S., and Kim, S. W., 1984, Macromolecular diffusion through polymer membranes, Int. J. Pharm.22:229–255.
Satterfield, C. N., Colton, C. K., and Pitcher, W. H., Jr., 1973, Restricted diffusion of liquids within fine pores, AIChE J. 19:628–635
Sawhney, A. S., Pathak, C. P., and Hubbell, J. A., 1993, Bioerodible hydrogels based on photopolymerized poly(ethylene glycol)-co-(a-hydroxy acid) diacrylate macromers, Macromolecules 26:581–587.
Shah, S. S., Cha, Y., and Pitt, C. G., 1992, Poly(glycolic acid-co-DL-lactic acid): Diffusion or degradation controlled drug delivery?, J. Controlled Release 18:261–270.
Shalaby, W. S., and Park, K., 1990, Biochemical and mechanical characterization of enzyme-digestible hydrogels, Pharm. Res. 7:816–823.
Shalaby, W. S. W., Abdallah, A. A., Park, H., and Park, K., 1993, Loading of bovine serum albumin into hydrogels by an electrophoretic process and its potential application to protein drugs, Pharm. Res. 10(3):457–460.
Siegel, R. A., and Langer, R., 1984, Controlled release of polypeptides and other macromolecules, Pharm. Res. 1:2–10.
Smith, B. A., and Sefton, M. V., 1992, Thrombin and albumin adsorption to PVA and heparin-PVA hydrogels. I. Single protein isotherms, J. Biomed. Mater. Res. 26:947–958.
Smith, K. L., Baker, R. W., and Ninomiya, Y., 1983, Development of BioLure controlled release pheromone products, in: Controlled Release Delivery Systems (T. J. Roseman and S. Z. Mansdorf, eds.), Marcel Dekker, New York, pp. 325–335.
Stock, R. S., and Ray, W. H., 1985, Interpretation of photon correlation spectroscopy data: A comparison of analysis methods, J. Polym. Sci.: Polym. Phys. Ed 23:1393–1447.
Strzinar, I., and Sefton, M. V., 1992, Preparation and thrombogenicity of alkylated polyvinyl alcohol coated tubing, J. Biomed Mater. Res. 26:577–592.
Suzawa, T., and Murakami, T., 1980, Adsorption of bovine serum albumin on synthetic polymer latices, J. Colloid Interface Sci. 78(1):267–268.
Theeuwes, F., 1975, Elementary osmotic pump, J. Pharm. Sci. 64:1987–1991.
Thissen, J. P., Underwood, L. E., Maiter, D., Maes, M., Clemmons, D. R., and Ketelslegers, J.M., 1991, Failure of insulin-like growth factor-I (IGF-I) infusion to promote growth in protein-restricted rats despite normalization of serum IGF-I concentrations, Endocrinology 128:885–890.
Zentner, G. M., Cardinal, J. R., and Gregonis, D. E., 1979, Progestin permeation through polymer membranes III: Polymerization solvent effect on progesterone permeation through hydrogel membranes, J. Pharm. Sci. 68(6):794–797.
Zhu, K. J., Xiangzhou, L., and Shih, Y., 1990, Preparation, characterization, and properties of polylactide (PLA)-poly(ethylene glycol) (PEG) copolymers: A potential drug carrier, J. Appl. Polym. Sci. 39:1–9.
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am Ende, M.T., Mikos, A.G. (2002). Diffusion-Controlled Delivery of Proteins from Hydrogels and Other Hydrophilic Systems. In: Sanders, L.M., Hendren, R.W. (eds) Protein Delivery. Pharmaceutical Biotechnology, vol 10. Springer, Boston, MA. https://doi.org/10.1007/0-306-46803-4_5
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