Design Study and Feasibility of Hyperthermia Technique

  • Jaswantsing RajputEmail author
  • Anil Nandgaonkar
  • Sanjay Nalbalwar
  • Abhay Wagh
Conference paper
Part of the Advances in Intelligent Systems and Computing book series (AISC, volume 1025)


This paper briefly discusses the hyperthermia technique, useful for cancer treatment. This novel approach needs to be implemented over the existing cancer treatment such as radio therapy. This paper highlights the design study and feasibility of hyperthermia technique. The bio-heat equation is used to analyze the thermal effects on the human tissue by considering the variation in the body temperature. This novel modified equation is modeled and simulated using MATLAB software. Also this paper highlights the existing work from various laboratory and deep understanding of literatures. The bio-heat equation is modified for its usefulness in achieving higher accuracy in the operating temperature and stability in the design of hyperthermia machine.


Hyperthermia Tumor Tissue Cancer Hyperthermia treatment (HT) Magnetic nanoparticles (MNPs) 


  1. 1.
    Nguyen, P.T., Abbosh, A.M., Crozier, S.: 3-D focused microwave hyperthermia for breast cancer treatment with experimental validation. IEEE Tran. Ant. Prop. 65(7), 3489–3499 (2017)Google Scholar
  2. 2.
    Nguyen, P.T., Crozier, S., Abbosh, A.: Realistic simulation environment to test microwave to test microwave hyperthermia treatment of breast cancer. In. Proceedings of IEEE International Symposium on Antennas and Propagation, pp. 1188–1189 (2014)Google Scholar
  3. 3.
    Nguyen, P.T., Crozier, S., Abbosh, A.: Microwave hyperthermia tested on realistic breast models and antenna arrays. IEEE Trans. Ant. Prop. 99, 1 (2015)zbMATHGoogle Scholar
  4. 4.
    Nguyen, P.T., Abbosh, A.: Focusing techniques in breast cancer treatment using non-invasive microwave hyperthermia. In. Proceedings of IEEE International symposium of antennas and Propagation, pp. 1–3 (2015)Google Scholar
  5. 5.
    Nguyen, P.T., Crozier, S., Abbosh, A.: Thermo-dielectric breast phantom for experimental studies of microwave hyperthermia. IEEE Antennas Wirel. Propag. Lett. 476–479 (2015)Google Scholar
  6. 6.
    Nguyen, P.T., Crozier, S., Abbosh, A.: Three-dimensional microwave hyperthermia for breast cancer in a realistic environment using particle swarm optimization. IEEE Trans. Biomed. Eng. 64(6), 1335–1344 (2017)CrossRefGoogle Scholar
  7. 7.
    Kampinga, H.H.: Cell biological effects of hyperthermia alone or combined with radiation or drugs: A short introduction to newcomers in the field. Int. J. Hyperthermia 22, 191–196 (2006)CrossRefGoogle Scholar
  8. 8.
    Martin, G.T., et al.: Thermal model for the local microwave hyperthermia treatment of benign prostatic hyperplasia. IEEE Trans. Biomed. Eng. 39(8), 836–844 (1992)CrossRefGoogle Scholar
  9. 9.
    Lyons, B.E., et al.: Localized hyperthermia in the treatment of malignant brain tumors using an interstitial microwave antenna array. IEEE Trans. Biomed. Eng. BME-31(1), 53–62 (1984)Google Scholar
  10. 10.
    Cavagnaro, M., et al.: A minimally invasive antenna for microwave ablation therapies: Design, performances, and experimental assessment. IEEE Trans. Biomed. Eng. 58(4), 949–959 (2011)CrossRefGoogle Scholar
  11. 11.
    Kok, H., et al.: Current state of the art of regional hyperthermia treatment planning: A review. Radiat. Oncol.10 (2015)Google Scholar
  12. 12.
    Tang, Y.-D., Flesch, R.C., Jin, T.: Injection strategy for the optimization of therapeutic profile considering irregular tumors in magnetic hyperthermia. IEEE Trans. Magnetics 54(6) (2018)Google Scholar
  13. 13.
    Salloum, M., Ma, R.H., Weeks, D., Zhu, L.: Controlling nanoparticle delivery in magnetic nanoparticle hyperthermia for cancer treatment: Experimental study in agarose gel. Int. J. Hyperthermia 24(4), 337–345 (2008)CrossRefGoogle Scholar
  14. 14.
    Patankar, S.: Numerical heat transfer and fluid flow. vol. 1, pp. 137–139. CRC Press (1980).
  15. 15.
    Parker, K.J.: Effects of heat conduction and sample size on ultrasonic absorption measurements. J. Acoust. Soc. Am. 77, 719 (1985)

Copyright information

© Springer Nature Singapore Pte Ltd. 2020

Authors and Affiliations

  • Jaswantsing Rajput
    • 1
    Email author
  • Anil Nandgaonkar
    • 2
  • Sanjay Nalbalwar
    • 2
  • Abhay Wagh
    • 3
  1. 1.Ramrao Adik Institute of TechnologyNavi MumbaiIndia
  2. 2.Dr. Babasaheb, Ambedkar Technolgical UniversityLonereIndia
  3. 3.DTEMumbaiIndia

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