Methods for the Detection and Quantification of Quorum-Sensing Signals in Food Spoilage

  • A. M. V. N. Prathyusha
  • Harish Annavarapu
  • Pallaval Veera BramhachariEmail author


Food spoilage is a complex process occurs due to microbial activities. Microorganisms synthesize several proteolytic, pectinolytic, lipolytic and saccharolytic enzymes whose activity is associated with deterioration of foods. The synthesis of these enzymes is controlled by quorum sensing (QS) signifying a possible role of cell-to-cell communication in spoilage of foods. A diverse variety of Gram-negative and Gram-positive bacterial species coordinate communal behaviour based on population density. Microbes communicate among them by producing the signalling molecules, Quorum-sensing molecules (QSM). This review focuses on QS molecules and techniques for their detection and quantification.


Quorum-sensing molecules Food spoilage Quantitative analysis 



Dr. Bramhachari and colleagues are grateful to Krishna University, Machilipatnam, for the extended support.

Conflict of Interest

The authors declare that they have no competing interests.


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© Springer Nature Singapore Pte Ltd. 2019

Authors and Affiliations

  • A. M. V. N. Prathyusha
    • 1
  • Harish Annavarapu
    • 2
  • Pallaval Veera Bramhachari
    • 1
    Email author
  1. 1.Department of BiotechnologyKrishna UniversityMachilipatnamIndia
  2. 2.Department of Food and Nutritional SciencesAcharya Nagarjuna UniversityGunturIndia

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