Hypertrophic Scars and Keloids
Overexpression of fibrous tissue results in formation of hypertrophic scars and keloids. Normal apoptosis of fibroblasts is lacking in such abnormal scars. Chest wall scars and scars crossing the joints have more chances to be hypertrophic. This also leads to joint contractures.
These scars can be managed by pressure garments, pressure bandages, local application of silicone gel material and certain local creams. Steroid injections, 5-fluorouracil injection help in regression of keloids.