The Indoor Environment in Schools, Kindergartens and Day Care Centres

  • Motoko TakaokaEmail author
  • Dan Norbäck
Part of the Current Topics in Environmental Health and Preventive Medicine book series (CTEHPM)


Schools and day care centres (also called kindergartens) are important indoor environments for children. There is evidence that the indoor environment in day care centres and schools can increase asthma, asthmatic symptoms, rhinitis and other medical symptoms (e.g. eye irritation, dermal symptoms, headache and fatigue) among children. The indoor environment may also affect teachers and other staff. Moreover, impaired indoor environment in schools may impair learning and mental ability among school children. Ventilation flow should fulfil current general ventilation standards for indoor environments. Installation of a mechanical ventilation system is the safest way to ensure sufficient ventilation flow. Control of room temperature and effective cleaning routines are other important measures to improve the indoor environment. Exposure to building dampness and indoor microbial growth should be avoided and occurrence of indoor mould and bacteria should be minimized. Chemical emissions from building materials should be reduced by selecting low emitting materials and consumer products. Wall-to-wall carpets should not be used in schools and day care centres since they are difficult to clean and can accumulate allergens and microbial compounds. Schools and day care centres buildings should be located away from heavy trafficked roads to reduce exposure to traffic air pollution. Since children are a sensitive subgroup of the population, schools and day care centres should meet high standards for indoor environment and indoor air quality.


Dampness School environment Day care centres Asthma Allergy 


  1. 1.
    Bröms K, Svardsudd K, Sundelin C, Norback D. A nationwide study of indoor and outdoor environments in allergen avoidance and conventional day care centers in Sweden. Indoor Air. 2006;16:227–35.PubMedCrossRefGoogle Scholar
  2. 2.
    Salo PM, Sever ML, Zeldin DC. Indoor allergens in school and day care environments. J Allergy Clin Immunol. 2009;124:185–92.PubMedPubMedCentralCrossRefGoogle Scholar
  3. 3.
    Zahradnik E, Raulf M. Animal allergens and their presence in the environment. Front Immunol. 2014;5:76.PubMedPubMedCentralCrossRefGoogle Scholar
  4. 4.
    Zhukovsky M, Vasilyev A, Onishchenko A, Yarmoshenko I. Review of indoor radon concentrations in schools and kindergartens. Radiat Prot Dosim. 2018;181:6–10.CrossRefGoogle Scholar
  5. 5.
    Malliari E, Kalantzki OI. Children’s exposure to brominated flame retardants in indoor environments- a review. Environ Int. 2017;108:146–69.PubMedCrossRefGoogle Scholar
  6. 6.
    Morawska L, Ayoko GA, Bae GN, Buonanno G, Chao CYH, Clifford S, Fu SC, Hänninen O, He C, Isaxon C, Mazaheri M, Salthammer T, Waring MS, Wierzbicka A. Airborne particles in indoor environments of homes, schools, offices and aged care facilities. The main routes of exposure. Environ Int. 2017;108:75–83.PubMedCrossRefGoogle Scholar
  7. 7.
    Daisey JM, Angell WJ, Apte MG. Indoor air quality, ventilation and health symptoms in schools: an analysis of existing information. Indoor Air. 2003;13:53–64.PubMedCrossRefGoogle Scholar
  8. 8.
    Mendell MJ, Heath GA. Do indoor pollutants and thermal conditions in schools influence student performance? A critical review of the literature. Indoor Air. 2005;15:27–52.PubMedCrossRefGoogle Scholar
  9. 9.
    Wargocki P, Wyon DP. Providing better thermal and air quality conditions in school classrooms would be cost-effective. Build Environ. 2013;59:581–9.CrossRefGoogle Scholar
  10. 10.
    Annesi-Maesano I, Baiz N, Banerjee S, Rudnai P, Rive S, SINPHIONIE Group. Indoor air quality and sources in schools and related health effects. J Toxicol Environ Health B Crit Rev. 2013;16:491–550.PubMedCrossRefGoogle Scholar
  11. 11.
    Salthammer T, Uhde E, Schripp T, Schieweck A, Morawska L, Mazaheri M, Clifford S, He C, Buonanno G, Querol X, Viana M, Kumar P. Children’s well-being at schools: impact of climatic conditions and air pollution. Environ Int. 2016;94:196–210.PubMedCrossRefGoogle Scholar
  12. 12.
    Esty B, Phipatanakul W. School exposure and asthma. Ann Allergy Asthma Immunol. 2018;120:482–7.PubMedPubMedCentralCrossRefGoogle Scholar
  13. 13.
    Salonen H, Salthammer T, Morawska L. Human exposure to ozone in school and office indoor environments. Environ Int. 2018;119:503–14.PubMedCrossRefGoogle Scholar
  14. 14.
    Herrick RF, Stewart JH, Allen JG. Review on PCBs in US schools: a brief history, an estimate of the number of impacted schools, and an approach for evaluating indoor air samples. Environ Sci Pollut Res Int. 2016;23:1975–85.PubMedCrossRefGoogle Scholar
  15. 15.
    Brown KW, Minegishi T, Cummiskey CC, Fragala MA, Hartman R, MacIntosh DL. PCB remediation in schools: a review. Environ Sci Pollut Res Int. 2016;23:1986–97.PubMedCrossRefGoogle Scholar
  16. 16.
    Fisk WJ. The ventilation problem in schools: literature review. Indoor Air. 2017;27:1039–51.PubMedCrossRefGoogle Scholar
  17. 17.
    Nafstad P, Jaakkola JJ, Skrondal A, Magnus P. Day care center characteristics and children’s respiratory health. Indoor Air. 2005;15:69–75.PubMedCrossRefGoogle Scholar
  18. 18.
    Ruotsalainen R, Jaakkola N, Jaakkola JJ. Dampness and molds in day-care centers as an occupational health problem. Int Arch Occup Environ Health. 1995;66:369–74.PubMedCrossRefGoogle Scholar
  19. 19.
    Li CS, Hsu CW, Lu CH. Dampness and respiratory symptoms among workers in day care centers in a subtropical climate. Arch Environ Health. 1997;52:68–71.PubMedCrossRefGoogle Scholar
  20. 20.
    Koskinen O, Husman T, Hyvärinen A, Reponen T, Nevalainen A. Respiratory symptoms and infections among children in a day-care center with mould problems. Indoor Air. 1995;5:3–9.CrossRefGoogle Scholar
  21. 21.
    Smedje G, Norbäck D, Edling C. Asthma among secondary school pupils in relation to the school environment. Clin Exp Allergy. 1997;27:1270–8.PubMedCrossRefGoogle Scholar
  22. 22.
    Cai GH, Jamal HH, Hashim Z, Ali F, Bloom E, Larsson L, Lampa E, Norbäck D. Fungal DNA, allergens, mycotoxins and associations with asthmatic symptoms among pupils in schools in Johor Bahru, Malaysia. Pediatr Allergy Immunol. 2011;22:290–7.PubMedCrossRefGoogle Scholar
  23. 23.
    Norbäck D, Hashim JH, Hashim Z, Cai G-H, Sooria V, Ismail SA, Wieslander G. Respiratory symptoms and fractional exhaled nitric oxide (FeNO) among students in Penang, Malaysia in relation to signs of dampness at school and fungal DNA in school dust. Sci Total Environ. 2017;577:148–54.PubMedCrossRefGoogle Scholar
  24. 24.
    Mi YH, Norbäck D, Tao J, Mi YL, Ferm M. Current asthma and respiratory symptoms among pupils in Shanghai, China: influence of building ventilation, nitrogen dioxide, ozone, and formaldehyde in classrooms. Indoor Air. 2006;16:454–64.PubMedCrossRefGoogle Scholar
  25. 25.
    Simoni M, Cai GH, Norback D, Annesi-Maesano I, Lavaud F, Sigsgaard T, Wieslander G, Nystad W, Canciani M, Viegi G, Sestini P. Total viable moulds and fungal DNA in classrooms and associations with respiratory health and pulmonary function of European schoolchildren. Pediatr Allergy Immunol. 2011;22:843–52.PubMedCrossRefGoogle Scholar
  26. 26.
    Haverinen-Shaughnessy U, Borras-Santos A, Turunen M, Zock JP, Jacobs J, Krop EJ, Casas L, Shaughnessy R, Täubel M, Heederik D, Hyvärinen A, Pekkanen J, Nevalainen A, HITEA Study Group. Occurrence of moisture problems in schools in three countries from different climatic regions in Europe based on questionnaires and building inspections - the HITEA study. Indoor Air. 2012;22:457–66.PubMedCrossRefGoogle Scholar
  27. 27.
    Jacobs J, Borras-Santos A, Krop E, Täubel M, Leppänen H, Haverinen-Shaugnessy U, Pekkanen J, Hyvärinen A, Doekes G, Zock JP, Heederik D. Dampness, bacterial and fungal component in dust in primary schools and respiratory health in school children across Europe. Occup Environ Med. 2014;71:704–12.PubMedCrossRefGoogle Scholar
  28. 28.
    Claudio L, Rivera GA, Ramirez OF. Association between markers of classroom environmental conditions and teachers’ respiratory health. J Sch Health. 2016;86:444–51.PubMedCrossRefGoogle Scholar
  29. 29.
    Dangman KH, Bracer AL, Storey E. Work-related asthma in teachers in Connecticut: association with chronic water damage and fungal growth in schools. Conn Med. 2005;69:9–17.PubMedGoogle Scholar
  30. 30.
    Ebbehøj M, Meyer HW, Würtz H, Suadicani P, Valbjørn O, Sigsgaard T, Gyntelberg E, Member of the Working group under the Danish Mold in Buildings Program (DAMIB). Mould in floor dust, building-related symptoms, and lung function among male and female schoolteachers. Indoor Air. 2005;15(Suppl 10):7–16.PubMedCrossRefPubMedCentralGoogle Scholar
  31. 31.
    Wålinder R, Norbäck DF, Wieslander G, Smedje G, Erwall C, Venge P. Acoustic rhinometry and lavage biomarkers in relation to some building characteristics in Swedish schools. Indoor Air. 2001;11:2–9.PubMedCrossRefPubMedCentralGoogle Scholar
  32. 32.
    Ahman M, Lundin A, Musabasic V, Söderman E. Improved health after intervention in a school with moisture problems. Indoor Air. 2000;10:57–62.PubMedCrossRefPubMedCentralGoogle Scholar
  33. 33.
    Sauni R, Verbeek JH, Uitti J, Jauhiainen M, Kreiss K, Sigsgaard T. Remediating buildings damaged by dampness and mould for preventing or reducing respiratory tract symptoms, infections and asthma. Cochrane Database Syst Rev. 2015;8(3):CD007897.Google Scholar
  34. 34.
    Roda C, Barral S, Ravelomanantsoa H, Dusseaux NM, Tribout M, Le Moullec Y, Momas I. Assessment of indoor environments in Paris child day centers. Environ Res. 2011;111:1010–7.PubMedCrossRefPubMedCentralGoogle Scholar
  35. 35.
    Aydogdu H, Asan A. Airborne fungi in child day care centers in Edirne City, Turkey. Environ Monit Assess. 2008;147:423–44.PubMedCrossRefGoogle Scholar
  36. 36.
    Aydogdu H, Asan A, Otkun MT. Indoor and outdoor airborne bacteria in child day-care centers in Edirne City (Turkey), seasonal distribution and influence of meteorological factors. Environ Monit Assess. 2010;164:53–66.PubMedCrossRefGoogle Scholar
  37. 37.
    Luksamijarulkul P, Ratthanakhot Y, Vatanasomboon P. Microbial counts and particulate matter levels in indoor air samples collected from a child home care center in Bangkok, Thailand. J Med Assoc Thail. 2012;95(Suppl 6):S161–8.Google Scholar
  38. 38.
    Mendes A, Aelenei D, Papoila AL, Carrerio-Martins P, Aguilar L, Pereira C, Neves P, Azevedo S, Cano M, Proenca C, Viegas J, Silva S, Mendes D, Neuparth N, Teixerira JP. Environmental and ventilation assessment in child day care centers in Porto: the ENVIRH project. J Toxicol Environ Health A. 2014;77:931–43.PubMedCrossRefGoogle Scholar
  39. 39.
    Lis DO, Gorny RL. Haemophilus influenzae as an airborne contamination in child day care centers. Am J Infect Control. 2013;41:438–42.PubMedCrossRefPubMedCentralGoogle Scholar
  40. 40.
    Pijnacker R, Mughini-Gras L, Vennema H, Enserink R, Van den Wijngaard CC, Kortbeek T, van Pelt W. Characteristics of child daycare centres associated with clustering of major enteropathogens. Epidemiol Infect. 2016;144:2527–39.PubMedCrossRefGoogle Scholar
  41. 41.
    Oldfield K, Siebers R, Crane J. Endotoxin and indoor allergen levels in kindergarten and day care centers in Wellington, New Zealand. N Z Med J. 2007;129:U2400.Google Scholar
  42. 42.
    Instanes C, Hetland G, Berntsen S, Løvik M, Nafstad P. Allergens and endotoxin in settled dust from day-care centers and schools in Oslo, Norway. Indoor Air. 2005;15:356–62.PubMedCrossRefGoogle Scholar
  43. 43.
    Cai GH, Bröms K, Mälarstig B, Zhao ZH, Kim JL, Svärdsudd K, Janson C, Norbäck D. Quantitative PCR analysis of fungal DNA in Swedish day care centers and comparison with building characteristics and allergen levels. Indoor Air. 2009;19:392–400.PubMedCrossRefGoogle Scholar
  44. 44.
    Cai GH, Mälarstig B, Kumlin A, Johansson I, Norbäck D. Fungal DNA and pet allergen levels in Swedish day care centres and associations with building characteristics. J Environ Monit. 2011;13:2018–24.PubMedCrossRefGoogle Scholar
  45. 45.
    Shin SK, Kim J, Ha SM, Oh HS, Chun J, Sohn J, Yi H. Metagenomic insights into the bioaerosols in the indoor and outdoor environments of childcare facilities. PLoS One. 2015;10:e0126960.PubMedPubMedCentralCrossRefGoogle Scholar
  46. 46.
    Godwin C, Batterman S. Indoor air quality in Michigan schools. Indoor Air. 2007;17:109–21.PubMedCrossRefPubMedCentralGoogle Scholar
  47. 47.
    Kim JL, Elfman L, Wieslander G, Smedje G, Norbäck D. Indoor moulds, bacteria, microbial volatile organic compounds (MVOC) and plasticizers in school: associations with asthma and respiratory symptoms in pupils. Indoor Air. 2007;17:153–63.PubMedCrossRefPubMedCentralGoogle Scholar
  48. 48.
    Norbäck D, Markowicz P, Cai GH, Hashim Z, Ali F, Zheng YW, Lai XX, Spangfort MD, Larsson L, Hashim JH. Endotoxin, ergosterol, fungal DNA and allergens in dust from schools in Johor Bahru, Malaysia-associations with asthma and respiratory infections in pupils. PLoS One. 2014;9:e883303.Google Scholar
  49. 49.
    Norbäck D, Hashim JH, Markowicz P, Cai GH, Hashim Z, Ali F, Larsson L. Endotoxin, ergosterol, muramic acid and fungal DNA in dust from schools in Johor Bahru, Malaysia – associations with rhinitis and sick building syndrome (SBS) in junior high school students. Sci Total Environ. 2016;545-546:95–103.PubMedCrossRefPubMedCentralGoogle Scholar
  50. 50.
    Zhao Z, Sebastian A, Larsson L, Wang Z, Zhang Z, Norbäck D. Asthmatic symptoms among pupils in relation to microbial dust exposure in schools in Taiyuan, China. Pediatr Allergy Immunol. 2008;19:455–65.PubMedCrossRefGoogle Scholar
  51. 51.
    Zhang X, Zhao Z, Nordqvist T, Larsson L, Sebastian A, Norbäck D. A longitudinal study of sick building syndrome among pupils in relation to microbial components in dust in schools in China. Sci Total Environ. 2011;409:5253–9.PubMedCrossRefGoogle Scholar
  52. 52.
    Jacobs JH, Krop EJ, Borras-Santos A, Zock JP, Taubel M, Hyvarinnen A, Pekkanen J, Doekes G, Heederik DJ, HITEA school study consortium. Endotoxin levels in settled airborne dust in European schools: the HITEA school study. Indoor Air. 2014;24:148–57.PubMedCrossRefGoogle Scholar
  53. 53.
    Norbäck D, Hashim JH, Cai GH, Hashim Z, Ali F, Bloom E, Larsson L. Rhinitis, throat and dermal symptoms, headache and tiredness among students in schools from Johor Bahru, Malaysia: associations with fungal DNA and mycotoxins in classroom dust. PLoS One. 2016;11:e01479976.CrossRefGoogle Scholar
  54. 54.
    Norbäck D, Hashim JH, Hashim Z, Sooria V, Ismail MS, Wieslander G. Ocular symptoms and tear film break up time (BUT) among junior high school students in Penang, Malaysia- associations with fungal DNA in school dust. Int J Hyg Environ Health. 2017;220:697–703.PubMedCrossRefGoogle Scholar
  55. 55.
    Peitzsch M, Sulyok M, Täubel M, Vishwanath V, Krop E, Borras-Santos A, Hyvärinen A, Nevalainen A, Krska R, Larsson L. Microbial secondary metabolites in school buildings inspected for moisture damage in Finland, The Netherlands and Spain. J Environ Monit. 2012;14:2044–53.PubMedCrossRefGoogle Scholar
  56. 56.
    Norback D, Cai GH, Kreft I, Lampa E, Wieslander G. Fungal DNA in dust in Swedish day care centres: associations with respiratory symptoms, fractional exhaled nitric oxide (FeNO) and C-reactive protein (CRP) in serum among day care Centre staff. Int Arch Occup Environ Health. 2016;89:331–40.PubMedCrossRefGoogle Scholar
  57. 57.
    Meyer HW, Würtz H, Suadicani P, Valbjørn O, Sigsgaard T, Gyntelberg F, Members of a Working Group under the Danish Mould in Buildings program (DAMIB). Molds in floor dust and building-related symptoms in adolescent school children. Indoor Air. 2004;14:65–72.PubMedCrossRefGoogle Scholar
  58. 58.
    Smedje G, Norbäck D. Incidence of asthma diagnosis and self-reported allergy in relation to the school environment- a four-year follow-up study in schoolchildren. Int J Tuberc Lung Dis. 2001;5:1059–66.PubMedGoogle Scholar
  59. 59.
    Norbäck D, Wålinder R, Wieslander G, Smedje G, Erwall C, Venge P. Indoor air pollutants in schools: nasal patency and biomarkers in nasal lavage. Allergy. 2000;55:163–70.PubMedCrossRefGoogle Scholar
  60. 60.
    Jacobs JH, Krop EJ, de Wind S, Spithoven J, Heederik DJ. Endotoxin levels in homes and classrooms of Dutch school children and respiratory health. Europ Repir J. 2013;42:314–22.CrossRefGoogle Scholar
  61. 61.
    ASHRAE. ASHRAE standard 62–1999. Ventilation for acceptable indoor air quality. Atlanta: American Society of Heating, Refrigeration and Air conditioning Engineers Incorporation; 1999.Google Scholar
  62. 62.
    Kim JL, Elfman L, Wieslander G, Ferm M, Toren K, Norbäck D. Respiratory health among Korean pupils in relation to home, school and outdoor environment. J Korean Med Sci. 2011;26:166–73.PubMedPubMedCentralCrossRefGoogle Scholar
  63. 63.
    Zhang X, Zhao Z, Nordqvist T, Norback D. The prevalence and incidence of sick building syndrome in Chinese pupils in relation to the school environment: a two-year follow up study. Indoor Air. 2011;21:462–71.PubMedCrossRefGoogle Scholar
  64. 64.
    Zhang X, Li F, Zhang L, Zhao Z, Norback D. A longitudinal study of sick building syndrome (SBS) among pupils in relation to SO2, NO2, O3 and PM10 in schools in China. PLoS One. 2014;9:e112933.PubMedPubMedCentralCrossRefGoogle Scholar
  65. 65.
    Simoni M, Annesi-Maesano I, Sigsgaard T, Norbäck D, Wieslander G, Nystad W, Canciani M, Sestini P, Viegi G. School air quality related to dry cough, rhinitis, and nasal patency in children. Eur Respir J. 2010;35:742–9.PubMedCrossRefGoogle Scholar
  66. 66.
    Carreiro-Martins P, Viegas J, Papoila AL, et al. CO(2) concentration in day care centres is related to wheezing in attending children. Eur J Pediatr. 2014;173:1041–9.PubMedCrossRefGoogle Scholar
  67. 67.
    Zuraimi MS, Tham KW, Chew FT, Ooi PL. The effect of ventilation strategies of child care centres of indoor air quality and respiratory health of children in Singapore. Indoor Air. 2007;17:317–27.PubMedCrossRefGoogle Scholar
  68. 68.
    Zuraimi MS, Ong TC, Tham KW, Chew FT. Determinants of indoor allergens in tropical child care centers. Pediatr Allergy Immunol. 2008;19:746–55.PubMedCrossRefGoogle Scholar
  69. 69.
    Norbäck D, Cai GH, Kreft I, Wieslander G. Cat, dog and horse allergens in Swedish day care centres-associations with fractional exhaled nitric oxide (FeNO) among day care centre staff. Glob J Health Sci. 2016;8:55725.CrossRefGoogle Scholar
  70. 70.
    Kim JL, Elfman L, Mi Y, Johansson M, Smedje G, Norbäck D. Current asthma and respiratory symptoms among pupils in relation to dietary factors and allergens in the school environment. Indoor Air. 2005;15:170–82.PubMedCrossRefGoogle Scholar
  71. 71.
    Kim JL, Elfman L, Norbäck D. Asthma and respiratory symptoms, and allergen levels in schools -comparison between Korea and Sweden. Indoor Air. 2007;17:122–9.PubMedCrossRefGoogle Scholar
  72. 72.
    Almqvist C, Wickman M, Perfetti L, Berglind N, Renström A, Hedrén M, Larsson K, Hedlin G, Malmberg P. Worsening of asthma in children allergic to cats, after indirect exposure to cat at school. Am J Respir Crit Care Med. 2001;163:694–8.PubMedCrossRefGoogle Scholar
  73. 73.
    Takaoka M, Suzuki K, Norbäck D. Current asthma, respiratory symptoms and airway infection among students in relation to the school and home environment in Japan. J Asthma. 2017;54:652–61.PubMedCrossRefGoogle Scholar
  74. 74.
    Quiros-Alcala L, Wilson S, Witherspoon N, Murray R, Perodin J, Trousdale K, Raspanti G, Sapkota A. Volatile organic compounds and particulate matter in child care facilities in the district of Columbia: results from a pilot study. Environ Res. 2016;146:116–24.PubMedCrossRefGoogle Scholar
  75. 75.
    Bradman A, Gaspar F, Castorina R, Williams J, Hoang T, Jenkins PL, McKione TE, Maddalena R. Formaldehyde and acetaldehyde exposure and risk characterization in California early childhood education environments. Indoor Air. 2017;27:104–13.PubMedCrossRefGoogle Scholar
  76. 76.
    Shendell DG, Prill R, Fisk WJ, Apte MG, Blake D, Faulkner D. Associations between classroom CO2 concentrations and student attendance in Washington and Idaho. Indoor Air. 2004;14:333–41.PubMedCrossRefGoogle Scholar
  77. 77.
    Fromme H, Heitmann D, Dietrich S, Schierl R, Körner W, Kiranoglu M, Zapf A, Twardella D. Air quality in schools - classroom levels of carbon dioxide (CO2), volatile organic compounds (VOC), aldehydes, endotoxins and cat allergen. Gesundheitswesen. 2008;70:88–97.PubMedCrossRefGoogle Scholar
  78. 78.
    Ichiba M, Takahashi T, Yamashita Z, Takaishi K, Nishimura K, Kamachi M, Kondoh T, Matsumoto A, Ueno D, Miyajima T. Approach to sick building problem in schools: a workshop “Saga Forum on Environment” project. Nippon Eiseigaku Zasshi. 2009;64:26–31.PubMedCrossRefGoogle Scholar
  79. 79.
    Hwang SH, Lee GB, Kim IS, Park WM. Formaldehyde and carbon dioxide air concentrations and their relationship with indoor environmental factors in daycare centers. J Air Waste Manag Assoc. 2017;67:306–12.PubMedCrossRefGoogle Scholar
  80. 80.
    Viet SM, Rogers J, Marker D, Fraser A, Friedman W, Jacobs D, Zhou Jm Tulve N. Lead, allergens, and pesticide levels in licensed child care centers in the United States. J Environ Health. 2013;76:8–14.PubMedGoogle Scholar
  81. 81.
    Raffy G, Mercier F, Blanchard O, Derbez M, Dassonville C, Bonvallot N, Glorennec P, Le Bot B. Semi-volatile organic compounds in the air and dust of 30 French schools: a pilot study. Indoor Air. 2017;27:114–27.PubMedCrossRefGoogle Scholar
  82. 82.
    Subedi B, Sullivan KD, Dhungana B. Phthalate and non-phthalate plasticizers in indoor dust from childcare facilities, salons, and homes across the USA. Environ Pollut. 2017;230:791–8.CrossRefGoogle Scholar
  83. 83.
    Olsen JH, Døssing M. Formaldehyde induced symptoms in day care centers. Am Ind Hyg Assoc J. 1982;43:366–370-384.PubMedCrossRefGoogle Scholar
  84. 84.
    Zhao Z, Zhang Z, Wang Z, Ferm M, Liang Y, Norbäck D. Asthmatic symptoms among pupils in relation to winter indoor and outdoor air pollution in schools in Taiyuan, China. Environ Health Perspect. 2008;116:90–7.PubMedCrossRefGoogle Scholar
  85. 85.
    Annesi-Maesano I, Hulin M, Lavaud F, Raherison C, Kopferschmitt C, de Blay C, Charpin DA, Denis C. Poor indoor air quality in classrooms related to asthma and rhinitis in primary school children of the French 6 cities study. Thorax. 2012;67:682–6.PubMedPubMedCentralCrossRefGoogle Scholar
  86. 86.
    Norbäck D, Hashim JH, Hashim Z, Ali F. Volatile organic compounds (VOC), formaldehyde and nitrogen dioxide (NO2) in schools in Johor Bahru, Malaysia: associations with rhinitis, ocular, throat and dermal symptom, headache and fatigue. Sci Total Environ. 2017;592:153–60.PubMedCrossRefGoogle Scholar
  87. 87.
    Wallner P, Kundi M, Moshammer H, Piegler K, Hohenblum P, Scharf S, Fröhlich M, Damberger B, Tappler P, Hutter HP. Indoor air in schools and lung function of Austrian school children. J Environ Monit. 2012;14:1976–82.PubMedCrossRefGoogle Scholar
  88. 88.
    Madureira J, Paciencia I, Rufo J, Ramos E, Barros H, Teixeira JP, Olivia FE. Indoor air quality in schools and its relationship with children’s respiratory symptoms. Atmos Environ. 2015;118:145–56.CrossRefGoogle Scholar
  89. 89.
    Siwarom S, Puranitee P, Plitponkarnpim A, Manuyakorn W, Sinitkul R, Arj-Ong VS. Association of indoor air quality and preschool children’s respiratory symptoms. Asian Pac J Allergy Immunol. 2017;35:119–26.PubMedGoogle Scholar
  90. 90.
    Carreiro-Martins P, Papoila AL, Caires I, Azevedo S, Cano MM, Virella D, Leiria-Pinto P, Teixeira JP, Rosado-Pinto J, Annesi-Maesano I, Neuparth N. Effect of indoor air quality of day care centers in children with different predisposition for asthma. Pediatr Allergy Immunol. 2016;27:299–306.PubMedCrossRefGoogle Scholar
  91. 91.
    Norbäck D, Torgen M, Edling C. Volatile organic compounds, respirable dust and personal factors related to prevalence and incidence of sick building syndrome in primary schools. Br J Ind Med. 1990;47:733–41.PubMedPubMedCentralGoogle Scholar
  92. 92.
    World Health Organisation (WHO). Health effects of air pollution: an overview. In: Air quality guidelines global update 2005: particulate matter, ozone, nitrogen dioxide and sulfur dioxide. Copenhagen: WHO Regional Office for Europe; 2006.Google Scholar
  93. 93.
    Gaspar FW, Maddalena R, Williams J, Castorina R, Wang ZM, Kumagai K, McKone TE, Bradman A. Ultrafine, fine, and black carbon particle concentration in California child-care facilities. Indoor Air. 2018;28:102–11.PubMedCrossRefGoogle Scholar
  94. 94.
    Zhang X, Fan Q, Bai X, Li T, Zhao Z, Fan X, Norbäck D. Levels of fractional exhaled nitric oxide in children in relation to air pollution in Chinese day care centers. Int J Tubercl Lung Dis. 2018;22:813–9.CrossRefGoogle Scholar
  95. 95.
    Lee SC, Chang M. Indoor and outdoor air quality investigation at schools in Hong Kong. Chemosphere. 2000;41:109–13.PubMedCrossRefGoogle Scholar
  96. 96.
    Fan XJ, Yang C, Zhang L, Fan Q, Li T, Bai X, Zhao ZH, Zhang X, Norback D. Asthma symptoms among Chinese children: the role of ventilation and PM10 exposure at school and home. Int J Tuberl Lung Dis. 2017;21:1187–93.CrossRefGoogle Scholar
  97. 97.
    Stranger M, Potgieter-Vermaak SS, Van Grieken R. Characterization of indoor air quality in primary schools in Antwerp, Belgium. Indoor Air. 2008;18:454–63.PubMedCrossRefGoogle Scholar
  98. 98.
    Oeder S, Jörres RA, Weichenmeier I, Pusch G, Schober F, Behrendt H, Schierl R, Kronseder A, Nowak D, Dietrich S, Fernadez-Caldas E, Lintelmann J, Zimmermann R, Lang G, Mages J, Fromme H, Butlers JT. Airborne indoor particles from schools are more toxic than outdoor particles. Am J Respr Cell Mol Biol. 2012;47:575–682.CrossRefGoogle Scholar
  99. 99.
    Takaoka M, Suzuki K, Norbäck D. Sick building syndrome among junior high school students in Japan in relation to the home and school environment. Global J Health Sci. 2015;8:46131.CrossRefGoogle Scholar
  100. 100.
    Wålinder R, Norbäck D, Wieslander G, Smedje G, Erwall C, Venge P. Nasal patency and lavage biomarkers in relation to settled dust and cleaning routines in schools. Scand J Work Environ Health. 1999;25:137–43.PubMedCrossRefGoogle Scholar
  101. 101.
    Norbäck D, Torgen M. A longitudinal study relating carpeting with sick building syndrome. Environ Int. 1989;15:129–35.CrossRefGoogle Scholar
  102. 102.
    Becher R, Øvrevik J, Schwarze PE, Nilsen S, Hongslo JK, Bakke JV. Do carpets impair indoor air quality and cause adverse health outcomes: a review. Int J Environ Res Public Health. 2018;23:E184.CrossRefGoogle Scholar
  103. 103.
    Wålinder R, Gunnarsson K, Runeson R, Smedje G. Physiological and psychological stress reactions in relation to classroom noise. Scand J Work Environ Health. 2007;33:260–6.PubMedCrossRefGoogle Scholar
  104. 104.
    Kuller R, Lindsten C. Health and behaviour of children in classrooms with and without windows. J Environ Psychol. 1992;12:305–17.CrossRefGoogle Scholar
  105. 105.
    ASHRAE. Ventilation for acceptable indoor air quality. Atlanta: American Society of Heating, Refrigerating and Air-Conditioning Engineers, Inc.; 1989. (Standard 62-1989).Google Scholar

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© Springer Nature Singapore Pte Ltd. 2020

Authors and Affiliations

  1. 1.Department of Biosphere Sciences, School of Human SciencesKobe CollegeNishinomiyaJapan
  2. 2.Department of Medical SciencesUppsala UniversityUppsalaSweden

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