Microbial Products and Biotechnological Applications Thereof: Proteins, Enzymes, Secondary Metabolites, and Valuable Chemicals

  • Fatemeh Dabbagh
  • Zahra Moradpour
  • Abdollah GhasemianEmail author


Microbial species are among prominent producers of useful natural products, which are a very diverse collection of molecules. These natural products or better defined as specialized metabolites occur in various structural and functional classes and have been used by humans historically for different purposes: pharmaceuticals, chemical industry, agriculture, food and feed sector, etc. To the best of our knowledge, only a small fraction of microbial products is exploited and yet remains a larger chest to be reached. The most advantageous microbial products not only are restricted to useful proteins and enzymes, antibiotics, antitumor agents, immunosuppressants but also include antivirals, anthelmintics, nutraceuticals, polymers, enzyme inhibitors, surfactants, bioherbicides, biopesticides, and many more agricultural and industrial products.

In this regard, the objective of this chapter is to focus attention on the world of microbial natural products and their application from a biotechnological point of view. Microbial sources, biological activities, structures, biodiscovery, and, to some extent, biosynthesis and genetic engineering of natural products obtained from microorganisms are reviewed.


Natural products Microbial diversity Proteins Enzymes Metabolites Bioactivity 


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Copyright information

© Springer Nature Singapore Pte Ltd. 2019

Authors and Affiliations

  • Fatemeh Dabbagh
    • 1
  • Zahra Moradpour
    • 2
  • Abdollah Ghasemian
    • 2
    Email author
  1. 1.Department of Pharmacognosy and Pharmaceutical Biotechnology, Faculty of PharmacyHormozgan University of Medical SciencesBandar AbbasIran
  2. 2.Department of Pharmaceutical Biotechnology, Faculty of PharmacyUrmia University of Medical ScienceUrmiaIran

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