Sickle Cell Retinopathy
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Sickle cell disease refers to a group of inherited hemoglobinopathies characterized by abnormal hemoglobin genes. The resulting abnormal hemoglobin protein results in sickling of erythrocytes, intravascular hemolysis, defective oxygen transport, and tissue damage due to ischemia and necrosis. Sickle cell disease manifests systemically in many organs such as the brain, lungs, heart, liver, spleen, kidneys, joints, bones, and skin (Yawn et al. 2014).
The authors would like to thank Mark Janowicz, Principal Ophthalmic Photographer at Illinois Eye and Ear Infirmary, University of Illinois at Chicago, for his expertise with the acquisition of images in this chapter.
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