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Fabrication of Stimuli-Responsive Polymers and their Composites: Candidates for Resorbable Sutures

  • Deepshikha Das
  • Neha Mulchandani
  • Amit Kumar
  • Vimal KatiyarEmail author
Chapter
  • 38 Downloads
Part of the Materials Horizons: From Nature to Nanomaterials book series (MHFNN)

Abstract

Sutures are known to facilitate wound healing and recently, a significant attention has been laid on the development of different classes of materials, their properties to enhance tissue approximation and wound closure. The advancements in the suture technology have introduced different types of sutures such as barbed sutures, antimicrobial sutures, drug-eluting sutures. The biostable and bioresorbable materials have received importance in augmentation and proper growth of the tissues due to their extraordinary characteristics. Furthermore, the biodegradable polymeric sutures have been explored for suture applications due to their efficiency, both in terms of property and application. In this regard, the current chapter highlights the various biodegradable polymers as possible candidates for sutures along with their essential properties and applications. Moreover, the utilization of different biofillers for fabricating sutures along with various fabrication techniques is discussed. Additionally, an impact is laid on the development of ‘stimuli-responsive sutures’ in order to tailor the behavior of the suture for subjected applications by using external agents or stimulus. These materials respond to small changes that can be both physical and chemical environment. Electric field, magnetic field, radiation are some of the stimulants that can be used based on the polymer used and nature of the application (cell adhesion, nerve regeneration, drug delivery, degradation control, antimicrobial, etc.) of suture. Magnetic responsive composite materials possess fine tuning properties which find their potential in biomedical, cell guidance and controlled drug release study (hyperthermia effect). A good understanding in terms of application and physical phenomena is portrayed which would help in developing the stimuli-responsive materials and devices in the biomedical field.

Keywords

Biodegradable polymers Composites Bioresorbable Stimuli-responsive sutures 

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© Springer Nature Singapore Pte Ltd. 2020

Authors and Affiliations

  • Deepshikha Das
    • 1
  • Neha Mulchandani
    • 1
  • Amit Kumar
    • 1
  • Vimal Katiyar
    • 1
    Email author
  1. 1.Department of Chemical EngineeringIndian Institute of Technology GuwahatiGuwahati, KamrupIndia

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