Chitosan-Based Systems in Tissue Engineering

  • M. Azeera
  • S. Vaidevi
  • J. Kumar
  • A. Shanmugarathinam
  • K. Ruckmani


Chitosan is a unique, naturally obtained polysaccharide derived from chitin. As a biomaterial, it attains immense interest for tissue engineering due to its biocompatibility and biodegradation which also exhibits desired properties such as bactericidal, fungicidal, and enhanced immune activity. Chitosan-based materials are mainly focused on fabricating scaffolds for tissue engineering. The ideal features of scaffolds are three-dimensional, highly porous, biocompatible, and bioresorbable, with cell attachment, proliferation, and implantation. Especially, these scaffolds have distinctive advantages, such as preservation of cellular binding and bioactive factor enrichment. This chapter highlights chitosan-based scaffolds and its composites having higher potential to be employed in bone, cartilage, liver, nerve, and musculoskeletal tissue engineering.


Chitosan Tissue engineering Biomaterials and scaffolds 



The authors wish to acknowledge the DST-sponsored National Facility for Drug Development (VI-D&P/349/10-11/TDT/1), Nanomission program of the Department of Science and Technology (DST), Ministry of Science and Technology of India (DST/SR/NM/NS-19/2009), and Technical Education Quality Improvement Programme (TEQIP-PHASE II) for their support in this work.


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© Springer Nature Singapore Pte Ltd. 2019

Authors and Affiliations

  • M. Azeera
    • 1
  • S. Vaidevi
    • 1
    • 2
  • J. Kumar
    • 1
  • A. Shanmugarathinam
    • 1
  • K. Ruckmani
    • 1
    • 2
  1. 1.Department of Pharmaceutical Technology, Centre for Excellence in Nanobio Translational Research (CENTRE)Anna UniversityTiruchirappalliIndia
  2. 2.National Facility for Drug Development for Academia, Pharmaceutical and Allied Industries (NFDD)Anna UniversityTiruchirappalliIndia

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