Ischemic Preconditioning

  • Shinya Minatoguchi


Brief episodes of ischemia and reperfusion precondition the myocardium and reduce the infarct size and following sustained ischemia. This phenomenon is termed as ischemic preconditioning (PC). PC is a powerful endogenous protection and has been demonstrated in dogs, pigs, rabbits and rats and humans. This protection is characterized as a reduction of infarct size and an improvement of postischemic cardiac dysfunction.


Brief episodes of ischemia and reperfusion Ischemic preconditioning Infarct size 


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Copyright information

© Springer Nature Singapore Pte Ltd. 2019

Authors and Affiliations

  • Shinya Minatoguchi
    • 1
  1. 1.Head of Heart Failure Center, Gifu Municipal HospitalEmeritus Professor, Gifu University Graduate School of MedicineGifuJapan

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