A Review of the Relationship Between Gut Microbiota and Memory

  • Amira Benmelouka
  • Ahmed M. Sherif
  • Mahmoud Ahmed EbadaEmail author


Alzheimer’s disease (AD) became a public health problem due to its increasing incidence and the dangerous sequences that affect society. Like many other neurodegenerative disorders, the complete mechanism of AD is not known yet. Scientists think that AD is caused by the combination of various factors related to the environment and the genetic basis. Many studies have demonstrated the role of human gut microbiota in different physiological and pathological pathways affecting many distant organs particularly the nervous system. Researchers observed a variety of disturbances of the intestinal microbiota homeostasis in many conditions such as diet changes, aging, probiotic and antibiotic administration. The study of this homeostasis and its different characteristics can help us understand the various mechanisms by which it influences the gut-brain axis. It also helps to find solutions to many health problems including neurodegenerative diseases.


Alzheimer’s disease Cognition Dementia Gut microbiota Memory Neurodegeneration Neuroinflammation 


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Copyright information

© Springer Nature Singapore Pte Ltd. 2019

Authors and Affiliations

  • Amira Benmelouka
    • 1
  • Ahmed M. Sherif
    • 2
  • Mahmoud Ahmed Ebada
    • 2
    Email author
  1. 1.University of AlgiersSidi M’HamedAlgeria
  2. 2.Faculty of MedicineZagazig UniversityZagazigEgypt

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