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Strengthen Alzheimer’s Awareness Through Biomusic

  • Panagiota Simou
  • Pavlos Vakalos
  • Athanasios AlexiouEmail author
  • Stylianos Chatzichronis
  • Mahmoud A. Ali
  • Ioannis Haranas
  • Ioannis Gkigkitzis
  • Abdul Hafeez
  • Asma Perveen
  • Ghulam Md Ashraf
Chapter

Abstract

A large number of neurodegenerative diseases, the age-related dementia, and the human frailty are caused, among others, from non-folding proteins and the aggregation of them leading to neuronal death. In the case of Alzheimer’s disease, a significant number of proteins like amyloid beta and tau seem to form unordered and problematic structures, leading through unknown mechanisms to pathological conditions and implications. Additionally, few studies have already shown the possibility of composing music sculptures retrieved from biological data, either for music audience or for cases of art therapy. In this study, we use a novel algorithm in order to present complex sound sculptures based on a hypothetical computerized interaction of amyloid beta and tau. The designed algorithm is completely adjustable, regarding several sound parameters, recognizing and emphasizing common patterns between the tested proteins for the generation of acoustic stimulus to the audience, and revealing Alzheimer’s complexity and tragedy.

Keywords

Alzheimer’s disease Amino acids Amyloid beta protein Art therapy Musical instrument digital interface Music neuroscience Neuroscience education Tau protein 

Notes

Conflict of Interest

The authors declare no conflict of interest.

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Copyright information

© Springer Nature Singapore Pte Ltd. 2019

Authors and Affiliations

  • Panagiota Simou
    • 1
  • Pavlos Vakalos
    • 2
  • Athanasios Alexiou
    • 1
    • 3
    Email author
  • Stylianos Chatzichronis
    • 4
    • 1
  • Mahmoud A. Ali
    • 5
  • Ioannis Haranas
    • 6
  • Ioannis Gkigkitzis
    • 7
  • Abdul Hafeez
    • 8
  • Asma Perveen
    • 9
  • Ghulam Md Ashraf
    • 10
    • 11
  1. 1.Novel Global Community Educational FoundationHebershamAustralia
  2. 2.Independent Musician-ResearcherThessalonikiGreece
  3. 3.AFNP MedWienAustria
  4. 4.Department of Informatics and Telecommunications, Bioinformatics ProgramNational and Kapodistrian University of AthensAthensGreece
  5. 5.Biotechnology Program, Faculty of AgricultureCairo UniversityGizaEgypt
  6. 6.Dept. of Physics and Computer ScienceWilfrid Laurier UniversityWaterlooCanada
  7. 7.NOVA, Department of MathematicsAnnandaleUSA
  8. 8.Glocal School of PharmacyGlocal UniversitySaharanpurIndia
  9. 9.Glocal School of Life SciencesGlocal UniversitySaharanpurIndia
  10. 10.King Fahd Medical Research CenterKing Abdulaziz UniversityJeddahSaudi Arabia
  11. 11.Department of Medical Laboratory Technology, Faculty of Applied Medical SciencesKing Abdulaziz UniversityJeddahSaudi Arabia

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