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Mycoses in Neonates and Children

  • Tanu SinghalEmail author
Chapter

Abstract

Children at risk for invasive fungal infections (IFI) include neonates, critically sick children, children on cancer chemotherapy/stem cell transplant and those with primary or acquired immunodeficiency (Table 7.1). Like adults, the incidence of IFI in children is also increasing due to increase in the ‘at-risk group’. But limited trial data and non-availability of many paediatric antifungal formulations complicate treatment of IFI in children even more than adults. The burden and outcome of paediatric IFI in Asian countries are likely to be worse than resource-rich settings due to poor infection control practices in neonatal and paediatric intensive care units, overuse of antibiotics, increased mold spore counts in the hospital environment and residential dwellings, tropical climate, malnutrition, advanced disease at diagnosis, reduced awareness, lack of appropriate diagnostic facilities and cost/availability of antifungal drugs. This write-up gives a bird’s eye view of IFI in children from an Asian perspective. While knowledge and attention to guidelines is essential, what is more important is to formulate diagnostic and treatment algorithms based on local epidemiology, resources and availability.

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Copyright information

© Springer Nature Singapore Pte Ltd. 2020

Authors and Affiliations

  1. 1.Kokilaben Dhirubhai Ambani Hospital and Medical Research InstituteMumbaiIndia
  2. 2.Department of PaediatricsKokilaben HospitalMumbaiIndia

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