Epidemiology of Superficial Fungal Infections in Asia
Abstract
Superficial fungal infections (SFIs) affect millions of people worldwide. The major causes of these infections include dermatophytes, non-dermatophyte molds (NDM), and yeasts. The etiological agents are restricted to stratum corneum. SFIs of importance include dermatophytosis, Malassezia associated infection, keratitis, and rare superficial fungal infection (tinea nigra and piedra). All the etiological agents have varied geographical distribution occurring in tropics where high humidity and hot climatic condition predominate. SFIs are also reported as epidemic infections in area of overcrowding and poor hygienic conditions. From the past two decades, the cases are increasingly being reported in patients undergoing transplants, chemotherapy and in immunocompromised patients. The epidemiology of SFIs in Asia is interesting as most of these regions have the climatic condition that supports the fungi to survive and proliferate.
References
- 1.Weitzman I, Summerbell RC. The dermatophytes. Clin Microbiol Rev. 1995;8:240–59.PubMedPubMedCentralCrossRefGoogle Scholar
- 2.Havlickova B, Czaika VA, Friedrich M. Epidemiological trends in skin mycoses worldwide. Mycoses. 2008;51:2–15.PubMedCrossRefPubMedCentralGoogle Scholar
- 3.Ajello L. Natural history of the dermatophytes and related fungi. Mycopathol Mycol Appl. 1974;53:93–110.PubMedCrossRefPubMedCentralGoogle Scholar
- 4.Ganeshkumar P, Sr M, Hemamalini M, Madhavan R, Lakshmanan A. Epidemiological and clinical pattern of dermatomycoses in rural India. Indian J Med Microbiol. 2015;33:134–6.PubMedCrossRefPubMedCentralGoogle Scholar
- 5.Khadka S, Sherchand JB, Pokharel DB, Pokhrel BM, Mishra SK, Dhital S, Rijal B. Clinicomycological characterization of superficial mycoses from a tertiary care hospital in Nepal. Dermatol Res Pract. 2016;2016:1–7.CrossRefGoogle Scholar
- 6.Hayette M-PP, Sacheli R. Dermatophytosis, trends in epidemiology and diagnostic approach. Curr Fungal Infect Rep. 2015;9:164–79.CrossRefGoogle Scholar
- 7.Majid I, Sheikh G, Kanth F, Hakak R. Relapse after oral terbinafine therapy in dermatophytosis: a clinical and mycological study. Indian J Dermatol. 2016;61:529–33.PubMedPubMedCentralCrossRefGoogle Scholar
- 8.Ahmed S, Jeelani S, Lanker A, Qayoom S, Sameem F. Relapse of cutaneous fungal infection in healthy individuals—a rising concern. Br J Med Med Res. 2016;11:1–8.Google Scholar
- 9.Sahoo AK, Mahajan R. Management of tinea corporis, tinea cruris, and tinea pedis: a comprehensive review. Indian Dermatol Online J. 2016;7:77–86.PubMedPubMedCentralCrossRefGoogle Scholar
- 10.Dogra S, Uprety S. The menace of chronic and recurrent dermatophytosis in India: is the problem deeper than we perceive? Indian Dermatol Online J. 2016;7:73–6.PubMedPubMedCentralCrossRefGoogle Scholar
- 11.Venkatesan G, Singh AJAR, Murugesan AG, Janaki C, Shankar SG. Trichophyton rubrum – the predominant etiological agent in human dermatophytoses in Chennai. India African J Microbiol Res. 2007;52:9–12.Google Scholar
- 12.Chakrabarti A, Sharma SC, Talwar P. Isolation of dermatophytes from clinically normal sites in patients with tinea cruris. Mycopathologia. 1992;120:139–41.PubMedCrossRefPubMedCentralGoogle Scholar
- 13.Rezaei-Matehkolaei A, Rafiei A, Makimura K, Gräser Y, Gharghani M, Sadeghi-Nejad B. Epidemiological aspects of dermatophytosis in Khuzestan, southwestern Iran, an update. Mycopathologia. 2016;181:547–53.PubMedCrossRefPubMedCentralGoogle Scholar
- 14.Balakumar S, Rajan S, Thirunalasundari T, Jeeva S. Epidemiology of dermatophytosis in and around Tiruchirapalli, Tamilnadu, India. Asian Pacific J Trop Dis. 2012;2:286–9.CrossRefGoogle Scholar
- 15.Garg A, Venkatesh V, Singh M, Pathak KP, Kaushal GP, Agrawal SK. Onychomycosis in central India: a clinicoetiologic correlation. Int J Dermatol. 2004;43:498–502.PubMedCrossRefPubMedCentralGoogle Scholar
- 16.Zhan P, Liu W. The changing face of dermatophytic infections worldwide. Mycopathologia. 2017;182:77–86.PubMedCrossRefPubMedCentralGoogle Scholar
- 17.Philpot CM. Geographical distribution of the dermatophytes: a review. J Hyg (Lond). 1978;80:301–13.CrossRefGoogle Scholar
- 18.Desai SC. Epidemic and clinical features of T. rubrum infections in the tropics. Int J Dermatol. 1966;5:222–4.CrossRefGoogle Scholar
- 19.Khan KA, Anwar AA. Study of 73 cases of tinea capitis and tinea favosa in adults and adolescents. J Invest Dermatol. 1968;51:474–7.PubMedCrossRefPubMedCentralGoogle Scholar
- 20.Bishnoi A, Vinay K, Dogra S. Emergence of recalcitrant dermatophytosis in India. Lancet Infect Dis. 2018;18:250–1.PubMedCrossRefPubMedCentralGoogle Scholar
- 21.Rudramurthy SM, Shankarnarayan SA, Dogra S, Shaw D, Mushtaq K, Paul RA, Narang T, Chakrabarti A. Mutation in the Squalene Epoxidase Gene of Trichophyton interdigitale and Trichophyton rubrum Associated with Allylamine Resistance. Antimicrob Agents Chemother. 2018;62:1–9.CrossRefGoogle Scholar
- 22.Martinez-Rossi NM, Peres NTA, Rossi A. Antifungal resistance mechanisms in dermatophytes. Mycopathologia. 2008;166:369–83.PubMedCrossRefPubMedCentralGoogle Scholar
- 23.Dogra S, Narang T. Emerging atypical and unusual presentations of dermatophytosis in India. Clin Dermatology Rev. 2017;1:12–8.CrossRefGoogle Scholar
- 24.Nenoff P, Verma SB, Vasani R, Burmester A, Hipler U-C, Wittig F, Krüger C, Nenoff K, Wiegand C, Saraswat A, Madhu R, Panda S, Das A, Kura M, Jain A, Koch D, Gräser Y, Uhrlaß S. The current Indian epidemic of superficial dermatophytosis due to Trichophyton mentagrophytes-A molecular study. Mycoses. 2019;62:336–56.PubMedCrossRefPubMedCentralGoogle Scholar
- 25.Verma S. Steroid modified tinea. BMJ. 2017;356:j973.PubMedCrossRefPubMedCentralGoogle Scholar
- 26.Verma S, Madhu R. The Great Indian epidemic of superficial dermatophytosis: an appraisal. Indian J Dermatol. 2017;62:227–36.PubMedPubMedCentralGoogle Scholar
- 27.Naglot A, Shrimali DD, Nath BK, Gogoi HK, Veer V, Chander J, Tewari R, Centre C. Recent trends of dermatophytosis in northeast india ( assam ) and interpretation with published studies. IntJCurrMicrobiolAppSci. 2015;4:111–20.Google Scholar
- 28.Kashyap B, Bhalla P, Kaur R. A five-year survey of onychomycosis in New Delhi, India: Epidemiological and laboratory aspects. Indian J Dermatol. 2009;52:39–42.CrossRefGoogle Scholar
- 29.Lavanya V, Solabannavar SS. Prevalence and socio-economic correlation of dermatophytes isolated from clinical samples in a tertiary care centre in South India. Asian J AdvBasicSci. 2015;4:1–4.Google Scholar
- 30.Singal A, Rawat S, Bhattacharya SN, Mohanty S, Baruah MC. Clinico-myocological profile of tinea capitis in North India and response to griseofulvin. J Dermatol. 2001;28:22–6.PubMedCrossRefPubMedCentralGoogle Scholar
- 31.Sachin K, Seema B. Clinico-mycological profiles of dermatophytosis in Jaipur, India. African J Microbiol Res. 2016;10:1477–82.CrossRefGoogle Scholar
- 32.Bhatia VK, Sharma PC. Epidemiological studies on Dermatophytosis in human patients in Himachal Pradesh, India. Springerplus. 2014;3:134–40.PubMedPubMedCentralCrossRefGoogle Scholar
- 33.Mattei AS, Beber MA, Madrid IM, Souza Mattei A. Dermatophytosis in small animals. SOJ Microbiol Infect Dis. 2014;2:1–6.CrossRefGoogle Scholar
- 34.Upendra Y, Sendur S, Keswani N, Pallava A. Prevalence of dermatoses among the tribal children studying in residential schools of South Chhattisgarh, India. Indian J Paediatr Dermatology. 2018;19:15–20.CrossRefGoogle Scholar
- 35.Singh A, Masih A, Khurana A, Singh P, Kumar GM, Hagen F, Jacques FM, Chowdhary A. High terbinafine resistance in Trichophyton interdigitale isolates in Delhi, India harbouring mutations in the squalene epoxidase gene. Mycoses. 2018;61:477–84.PubMedCrossRefPubMedCentralGoogle Scholar
- 36.Kannan P, Janaki C, Selvi GS. Prevalence of dermatophytes and other fungal agents isolated from clinical samples. Indian J Med Microbiol. 2006;24:212–5.PubMedPubMedCentralGoogle Scholar
- 37.Peerapur BV, Inamdar AC, Pushpa PV, Srikant B. Clinicomycological study of dermatophytosis in Bijapur. Indian J Med Microbiol. 2004;22:273–4.PubMedPubMedCentralGoogle Scholar
- 38.Kaur I, Thakur K, Sood A, Mahajan VK, Gupta PK. Clinico-mycological profile of clinically diagnosed cases of dertmatophytosis in North India- a prospective cross sectional study. IJHSR. 2016;6:54–60.Google Scholar
- 39.Pathania S, Rudramurthy SM, Narang T, Saikia UN, Dogra S. A prospective study of the epidemiological and clinical patterns of recurrent dermatophytosis at a tertiary care hospital in India. Indian J Dermatol Venereol Leprol. 2018;84:678–84.PubMedCrossRefPubMedCentralGoogle Scholar
- 40.Pathan N, Sharma R, Vyas L, Vyas A. A clinicomycological study of cutaneous mycoses in Sawai Man Singh Hospital of Jaipur, North India. Ann Med Health Sci Res. 2013;3:593–7.PubMedPubMedCentralCrossRefGoogle Scholar
- 41.Kaur I, Chaudhary A, Singh H. Clinico-microbiological aspects of tinea corporis in North India: emergence of Trichophyton tonsurans. Int J Res Dermatology. 2019;5:144–9.CrossRefGoogle Scholar
- 42.Maulingkar SV, Pinto MJW, Rodrigues S. A clinico-mycological study of dermatophytoses in Goa, India. Mycopathologia. 2014;178:297–301.PubMedCrossRefPubMedCentralGoogle Scholar
- 43.Sharma M, Sharma R. Profile of dermatophytic and other fungal infections in Jaipur. Indian J Microbiol. 2012;52:270–4.PubMedCrossRefPubMedCentralGoogle Scholar
- 44.Grover C, Arora P, Manchanda V. Tinea capitis in the pediatric population: A study from North India. Indian J Dermatol Venereol Leprol. 2010;76:527–32.PubMedCrossRefPubMedCentralGoogle Scholar
- 45.Cai W, Lu C, Li X, Zhang J, Zhan P, Xi L, Sun J, Yu X. Epidemiology of superficial fungal infections in Guangdong, Southern China: a retrospective study from 2004 to 2014. Mycopathologia. 2016;181:387–95.PubMedCrossRefPubMedCentralGoogle Scholar
- 46.Zhan P, Li D, Wang C, Sun J, Geng C, Xiong Z, Seyedmousavi S, Liu W, de Hoog GS. Epidemiological changes in tinea capitis over the sixty years of economic growth in China. Med Mycol. 2015;53:691–8.PubMedCrossRefPubMedCentralGoogle Scholar
- 47.Tao-Xiang N, Zhi-Cheng L, Sao-Mao W, Wen-Zhu L. Analysis of dermatomycoses in Lanzhou District of Northwestern China. Mycopathologia. 2005;160:281–4.PubMedCrossRefPubMedCentralGoogle Scholar
- 48.Ming PX, Ti YLX, Bulmer GS. Outbreak of Trichophyton verrucosum in China transmitted from cows to humans. Mycopathologia. 2006;161:225–8.PubMedCrossRefPubMedCentralGoogle Scholar
- 49.Deng S, Bulmer GS, Summerbell RC, De Hoog GS, Hui Y, Gräser Y. Changes in frequency of agents of tinea capitis in school children fromWestern China suggest slow migration rates in dermatophytes. Med Mycol. 2008;46:421–7.PubMedCrossRefPubMedCentralGoogle Scholar
- 50.Bassiri-Jahromi S, Khaksar A. Outbreak of tinea gladiatorum in wrestlers in Tehran (Iran). Indian J Dermatol. 2008;53:132–6.PubMedPubMedCentralCrossRefGoogle Scholar
- 51.Saham A, Mohammad H, Zomorodian K, Pakshir K, Badali H, Abdollah R, Ravandeh Mostafa SS. Molecular characterization and in vitro antifungal susceptibility of 316 clinical isolates of dermatophytes in Iran. Mycopathologia. 2016;181:89–95.CrossRefGoogle Scholar
- 52.Afshar P, Khodavaisy S, Kalhori S, Ghasemi M, Razavyoon T. Onychomycosis in North-East of Iran. Iran J Microbiol. 2014;6:98–103.PubMedPubMedCentralGoogle Scholar
- 53.Aghamirian MR, Ghiasian SA. A clinico-epidemiological study on tinea gladiatorum in Iranian wrestlers and mat contamination by dermatophytes. Mycoses. 2011;54:248–53.PubMedCrossRefPubMedCentralGoogle Scholar
- 54.Banik A, Durairaj E, Lyngdoh W, Khyriem AB, Sabhapandit D. Clinico-aetiologic profile of Onychomycoses in a tertiary care centre in northeast India. Trop Dr. 2018;48:136–42.CrossRefGoogle Scholar
- 55.Noguchi H, Hiruma M, Kawada A, Ishibashi A, Kono S. Tinea pedis in members of the Japanese Self-defence Forces: relationships of its prevalence and its severity with length of military service and width of interdigital spaces. Mycoses. 1995;38:494–9.PubMedCrossRefPubMedCentralGoogle Scholar
- 56.Noguchi H, Jinnin M, Miyata K, Hiruma M, Ihn H. Clinical features of 80 cases of tinea faciei treated at a rural clinic in Japan. Drug Discov Ther. 2014;8:245–8.PubMedCrossRefPubMedCentralGoogle Scholar
- 57.Bhat YJ, Zeerak S, Kanth F, Yaseen A, Hassan I, Hakak R. Clinicoepidemiological and mycological study of tinea capitis in the pediatric population of Kashmir valley: a study from a tertiary care centre. Indian Dermatol Online J. 2017;8:100–3.PubMedPubMedCentralCrossRefGoogle Scholar
- 58.Yehia MA, El-Ammawi TS, Al-Mazidi KM, El-Ela MAA, Al-Ajmi HS. The spectrum of fungal infections with a special reference to dermatophytoses in the Capital area of Kuwait during 2000-2005: A retrospective analysis. Mycopathologia. 2010;169:241–6.PubMedCrossRefPubMedCentralGoogle Scholar
- 59.Gupta AK, Mays RR, Versteeg SG, Piraccini BM, Takwale A, Shemer A, Babaev M, Grover C, Di Chiacchio NG, Taborda PRO, Taborda VBA, Shear NH, Piguet V, Tosti A. Global perspectives for the management of onychomycosis. Int J Dermatol. 2018:1–12.Google Scholar
- 60.Shahzad M, Alzolibani AA, Al Robaee AA, Bin Saif GA, Babikir IHK, Abdel-Magied EM, Elsayed AE. Onychomycosis in Qassim region of Saudi Arabia: A clinicoaetiologic correlation. J Clin Diagnostic Res. 2014;8:1–4.CrossRefGoogle Scholar
- 61.Gupta AK, Konnikov N, MacDonald P, Rich P, Rodger NW, Edmonds MW, McManus R, Summerbell RC. Prevalence and epidemiology of toenail onychomycosis in diabetic subjects: a multicentre survey. Br J Dermatol. 1998;139:665–71.PubMedCrossRefPubMedCentralGoogle Scholar
- 62.Aghamirian MR, Ghiasian SA. Onychomycosis in Iran: epidemiology, causative agents and clinical features. Japanese J Med Mycol. 2010;51:23–9.CrossRefGoogle Scholar
- 63.Borda LJ, Wikramanayake TC. Seborrheic dermatitis and dandruff: a comprehensive review. J Clin Investig dermatology. 2015;3Google Scholar
- 64.Otomi Cho AT. Molecular characterization of the skin fungal microbiota in patients with seborrheic dermatitis. J Clin Exp Dermatol Res. 2015;05:5–8.Google Scholar
- 65.Nakabayashi A, Sei Y, Guillot J. Identification of Malassezia species isolated from patients with seborrhoeic dermatitis, atopic dermatitis, pityriasis versicolor and normal subjects. Med Mycol. 2000;38:337–41.PubMedCrossRefPubMedCentralGoogle Scholar
- 66.Tajima M, Sugita T, Nishikawa A, Tsuboi R. Molecular analysis of Malassezia microflora in seborrheic dermatitis patients: comparison with other diseases and healthy subjects. J Invest Dermatol. 2008;128:345–51.PubMedCrossRefPubMedCentralGoogle Scholar
- 67.Jing W. A retrospective survey of mucocutaneous manifestations of HIV infection in Malaysia: analysis of 182 cases. J Dermatol. 2000;27:225–32.PubMedCrossRefPubMedCentralGoogle Scholar
- 68.Kim TG, Lee KH, Oh SH. Skin disorders in Korean patients infected with human immunodeficiency virus and their association with a CD4 lymphocyte count: a preliminary study. J Eur Acad Dermatology Venereol. 2010;24:1476–80.CrossRefGoogle Scholar
- 69.Wiwanitkit V. Prevalence of dermatological disorders in Thai HIV-infected patients correlated with different CD4 lymphocyte count statuses: a note on 120 cases. Int J Dermatol. 2004;43:265–8.PubMedCrossRefPubMedCentralGoogle Scholar
- 70.Rudramurthy SM, Honnavar P, Dogra S, Yegneswaran PP, Handa S, Chakrabarti A. Association of Malassezia species with dandruff. Indian J Med Res. 2014;139:431–7.PubMedPubMedCentralGoogle Scholar
- 71.Honnavar P, Prasad GS, Ghosh A, Dogra S, Handa S, Rudramurthy SM. Malassezia arunalokei sp. nov., a novel yeast species isolated from seborrheic dermatitis patients and healthy individuals from India. J Clin Microbiol. 2016;54:1826–34.PubMedPubMedCentralCrossRefGoogle Scholar
- 72.Sunenshine PJ, Schwartz RA, Janniger CK. Tinea versicolor. Int J Dermatol. 1998;37:648–55.PubMedCrossRefPubMedCentralGoogle Scholar
- 73.Schwartz RA. Superficial fungal infections. Lancet. 2004;364:1173–82.PubMedCrossRefPubMedCentralGoogle Scholar
- 74.Gupta AK, Bluhm R, Summerbell R. Pityriasis versicolor. J Eur Acad Dermatol Venereol. 2002;16:19–33.PubMedCrossRefPubMedCentralGoogle Scholar
- 75.Karray M, Mckinney WP. Tinea, versicolor pathophysiology treatment/management. StatPearls Publ. 2019:1–5.Google Scholar
- 76.Zeinali E, Sadeghi G, Yazdinia F, Shams-Ghahfarokhi M, Razzaghi-Abyaneh M. Clinical and epidemiological features of the genus malassezia in iran. Iran J Microbiol. 2014;6:354–60.PubMedPubMedCentralGoogle Scholar
- 77.Moallaei H, Namazi MJ, Bouchara JP, Pourhammed S. Malassezia species in students from universities of Sabzevar, Northeastern Iran. J Mycol Med. 2018;28:70–5.PubMedCrossRefPubMedCentralGoogle Scholar
- 78.He S, Du W, Yang S, Zhou S, Li W, Wang J, Xiao F, Xu S, Zhang X. The genetic epidemiology of tinea versicolor in China. Mycoses. 2008;51:55–62.PubMedPubMedCentralGoogle Scholar
- 79.Krisanty RIA, Bramono K, Made Wisnu I. Identification of Malassezia species from pityriasis versicolor in Indonesia and its relationship with clinical characteristics. Mycoses. 2009;52:257–62.PubMedCrossRefPubMedCentralGoogle Scholar
- 80.Vijayanand S. Characterization of Malassezia species isolated from Pityriasis versicolor patients and healthy subjects of North-east India by PCR-RFLP. Int J Recent Sci Res. 2017;8:16624–31.Google Scholar
- 81.Biswas Pramanik S, Chakraborty A, Nandi A, Banerjee M, Ghosh R, Bandopadhyay M, Banerjee D. A Study of Prevalence of Different Species of Malassezia Causing Pityriasis Versicolor and Sites of Distribution of Lesion in a Tertiary Care Hospital in Kolkata, India. IntJCurrMicrobiolAppSci. 2015;4:471–8.Google Scholar
- 82.Sharma A, Rabha D, Choraria S, Hazarika D, Ahmed G, Hazarika NK. Clinicomycological profile of pityriasis versicolor in Assam. Indian J Pathol Microbiol. 2016;59:159–65.PubMedCrossRefPubMedCentralGoogle Scholar
- 83.Chaudhary R, Singh S, Banerjee T, Tilak R. Prevalence of different Malassezia species in pityriasis versicolor in central India. Indian J Dermatol Venereol Leprol. 2010;76:159–64.PubMedCrossRefPubMedCentralGoogle Scholar
- 84.Kindo AJ, Sophia SKC, Kalyani J, Anandan S. Identification of Malassezia species. Indian J Med Microbiol. 2004;22:179–81.PubMedPubMedCentralGoogle Scholar
- 85.Prieto-Granada CN, Lobo AZC, Mihm MC. Skin infections. In: Diagnostic pathology of infectious disease. 1st ed. New York: Elsevier; 2010. p. 519–616.CrossRefGoogle Scholar
- 86.Akaza N, Akamatsu H, Sasaki Y, Kishi M, Mizutani H, Sano A, Hirokawa K, Nakata S, Nishijima S, Matsunaga K. Malassezia folliculitis is caused by cutaneous resident Malassezia species. Med Mycol. 2009;47:618–24.PubMedCrossRefPubMedCentralGoogle Scholar
- 87.Durdu M, Güran M, Ilkit M. Epidemiological characteristics of Malassezia folliculitis and use of the May-Grünwald-Giemsa stain to diagnose the infection. Diagn Microbiol Infect Dis. 2013;76:450–7.PubMedCrossRefPubMedCentralGoogle Scholar
- 88.Sutton DA, Rinaldi MG, Sanche SE. Dematiaceous fungi. Elsevier, 329–54; 2009.Google Scholar
- 89.Sarangi G, Dash D, Chayani N, Patjoshi S, Jena S. Bilateral tinea nigra of palm: a rare case report from Eastern India. Indian J Med Microbiol. 2014;32:86–8.PubMedCrossRefPubMedCentralGoogle Scholar
- 90.Tilak R, Singh S, Prakash P, Singh D, Gulati A. A case report of tinea nigra from North India. Indian J Dermatol Venereol Leprol. 2009;75:538.PubMedCrossRefPubMedCentralGoogle Scholar
- 91.Noguchi H, Hiruma M, Inoue Y, Miyata K, Tanaka M, Ihn H. Tinea nigra showing a parallel ridge pattern on dermoscopy. J Dermatol. 2015;42:518–20.PubMedCrossRefPubMedCentralGoogle Scholar
- 92.Chen GY, Cheng YW, Wang CY, Hsu TJ, Hsu ML, Yang PT, Chen WC. Prevalence of skin diseases among schoolchildren in Magong, Penghu, Taiwan: A community-based clinical survey. J Formos Med Assoc. 2008;107:21–9.PubMedCrossRefPubMedCentralGoogle Scholar
- 93.Shivaprakash MR, Singh G, Gupta P, Dhaliwal M, Kanwar AJ, Chakrabarti A. Extensive white piedra of the scalp caused by Trichosporon inkin: a case report and review of literature. Mycopathologia. 2011;172:481–6.PubMedCrossRefPubMedCentralGoogle Scholar
- 94.Khandpur S, Reddy BS. Itraconazole therapy for white piedra affecting scalp hair. J Am Acad Dermatol. 2002;47:415–8.PubMedCrossRefPubMedCentralGoogle Scholar
- 95.Al-Sogair SM, Moawad MK, Al-Humaidan YM. Fungal infection as a cause of skin disease in the Eastern Province of Saudi Arabia: prevailing fungi and pattern of infection. Mycoses. 2010;34:333–7.CrossRefGoogle Scholar
- 96.Kubec K, Dvorak R, Alsaleh QA. Trichosporosis (white piedra) in Kuwait. Int J Dermatol. 1998;37:186–7.PubMedCrossRefPubMedCentralGoogle Scholar
- 97.Adam BA, Soo-Hoo TS, Chong KC. Black piedra in west Malaysia. Australas J Dermatol. 1977;18:45–7.PubMedCrossRefPubMedCentralGoogle Scholar
- 98.Desai DH, Nadkarni NJ. Piedra: an ethnicity-related trichosis? Int J Dermatol. 2014;53:1008–11.PubMedCrossRefPubMedCentralGoogle Scholar
- 99.Venugopal PV, Venugopal TV. Superficial Mycoses in Saudi Arabia. Australas J Dermatol. 1992;33:45–8.PubMedCrossRefPubMedCentralGoogle Scholar
- 100.Thomas PA, Kaliamurthy J. Mycotic keratitis: epidemiology, diagnosis and management. Clin Microbiol Infect. 2013;19:210–20.PubMedCrossRefPubMedCentralGoogle Scholar
- 101.Radhakrishnan A (2011) Fungal Keratitis. 20–24.Google Scholar
- 102.Deorukhkar S, Katiyar R, Saini S. Epidemiological features and laboratory results of bacterial and fungal keratitis: A five-year study at a rural tertiary-care hospital in western Maharashtra, India. Singap Med J. 2012;53:264–7.Google Scholar
- 103.Bharathi MJ, Ramakrishnan R, Vasu S, Meenakshi R, Palaniappan R. Epidemiological characteristics and laboratory diagnosis of fungal keratitis. A three-year study. Indian J Ophthalmol. 2003;51:315–21.PubMedPubMedCentralGoogle Scholar
- 104.Wang L, Sun S, Jing Y, Han L, Zhang H, Yue J. Spectrum of fungal keratitis in central China. Clin Exp Ophthalmol. 2009;37:763–71.PubMedCrossRefPubMedCentralGoogle Scholar
- 105.Thomas PA. Fungal infections of the cornea. Eye. 2003;17:852–62.PubMedCrossRefPubMedCentralGoogle Scholar
- 106.Ghosh AK, Gupta A, Rudramurthy SM, Paul S, Hallur VK, Chakrabarti A. Fungal keratitis in North India: spectrum of agents, risk factors and treatment. Mycopathologia. 2016;181:843–50.PubMedCrossRefPubMedCentralGoogle Scholar
- 107.Manikandan P, Abdel-hadi A, Randhir Babu Singh Y, Revathi R, Anita R, Banawas S, Bin Dukhyil AA, Alshehri B, Shobana CS, Panneer Selvam K, Narendran V. Fungal keratitis: epidemiology, rapid detection, and antifungal susceptibilities of fusarium and aspergillus isolates from corneal scrapings. Biomed Res Int. 2019;2019:1–9.CrossRefGoogle Scholar
- 108.Khanal B, Kaini KR, Deb M, Badhu B, Thakur SK. Microbial keratitis in eastern Nepal. Trop Dr. 2001;31:168–9.CrossRefGoogle Scholar
- 109.Dunlop AA, Wright ED, Howlader SA, Nazrul I, Husain R, McClellan K, Billson FA. Suppurative corneal ulceration in Bangladesh. A study of 142 cases examining the microbiological diagnosis, clinical and epidemiological features of bacterial and fungal keratitis. Aust N Z J Ophthalmol. 1994;22:105–10.PubMedCrossRefPubMedCentralGoogle Scholar
- 110.Xie L, Zhong W, Shi W, Sun S. Spectrum of Fungal Keratitis in North China. Ophthalmology. 2006;113:1943–8.PubMedCrossRefPubMedCentralGoogle Scholar
- 111.Hasika R, Lalitha P, Radhakrishnan N, Rameshkumar G, Prajna NV, Srinivasan M. Pythium keratitis in South India: Incidence, clinical profile, management, and treatment recommendation. Indian J Ophthalmol. 2019;67:42–7.PubMedPubMedCentralCrossRefGoogle Scholar
- 112.Thanathanee O, Enkvetchakul O, Rangsin R, Waraasawapati S, Samerpitak K, Suwan-apichon O. Outbreak of Pythium keratitis during rainy season: a case series. Cornea. 2013;32:199–204.PubMedCrossRefPubMedCentralGoogle Scholar
- 113.Lekhanont K, Chuckpaiwong V, Chongtrakool P, Aroonroch R, Vongthongsri A. Pythium insidiosum keratitis in contact lens wear: a case report. Cornea. 2009;28:1173–7.PubMedCrossRefPubMedCentralGoogle Scholar
- 114.Joseph J, Sridhar MS, Murthy S, Sharma S. Clinical and Microbiological Profile of Microsporidial Keratoconjunctivitis in Southern India. Ophthalmology. 2006;113:531–7.PubMedCrossRefPubMedCentralGoogle Scholar
- 115.Joseph J, Vemuganti GK, Sharma S. Microsporidia: emerging ocular pathogens. Indian J Med Microbiol. 2005;23:80–91.PubMedCrossRefPubMedCentralGoogle Scholar
- 116.Reddy AK, Balne PK, Garg P, Krishnaiah S. Is microsporidial keratitis a seasonal infection in India? Clin Microbiol Infect. 2011;17:1114–6.PubMedCrossRefPubMedCentralGoogle Scholar
- 117.Shivaprakash MR, Appannanavar SB, Dhaliwal M, Gupta A, Gupta S, Gupta A, Chakrabarti A. Colletotrichum truncatum: an unusual pathogen causing mycotic keratitis and endophthalmitis. J Clin Microbiol. 2011;49:2894–8.PubMedPubMedCentralCrossRefGoogle Scholar
- 118.Joseph J, Fernandes M, Sharma S. Colletotrichum dematium keratitis. J Postgrad Med. 2004;50:309–10.PubMedPubMedCentralGoogle Scholar
- 119.Mendiratta D, Thamke D, Shukla A, Narang P. Keratitis due to Colletotrichum dematium - a case report. Indian J Med Microbiol. 2005;23:56.PubMedCrossRefPubMedCentralGoogle Scholar
- 120.Ali SY, Gajjala SR, Raj A. Study of prevalence of dermatophytes among human immunodeficiency virus/AIDS patients in Shadan Institute of Medical Sciences and Teaching Hospital and Research Centre, Hyderabad, Telangana, India. Indian J Sex Transm Dis AIDS. 2018;39:98–101.PubMedPubMedCentralCrossRefGoogle Scholar
- 121.Sen A, Bhunia D, Datta PK, Ray A, Banerjee P. A study of onychomycosis at a tertiary care hospital in Eastern Bihar. Indian J Dermatol. 2018;63:141–6.PubMedPubMedCentralGoogle Scholar
- 122.Asifa N, Farhath K. Current mycological profile of onychomycosis in Kashmir valley: A hospital-based study. J Lab Physicians. 2017;9:190.PubMedPubMedCentralCrossRefGoogle Scholar
- 123.Dabas Y, Xess I, Singh G, Pandey M, Meena S. Molecular identification and antifungal susceptibility patterns of clinical dermatophytes following CLSI and EUCAST guidelines. J Fungi (Basel, Switzerland). 2017:3, 17–27.PubMedCentralCrossRefGoogle Scholar
- 124.Sharma R, Adhikari L, Sharma RL. Recurrent dermatophytosis: A rising problem in Sikkim, a Himalayan state of India. Indian J Pathol Microbiol. 2017;60:541–5.PubMedCrossRefPubMedCentralGoogle Scholar
- 125.Manjunath M. Clinicomycological study of Dermatomycosis in a tertiary care hospital. Indian J Microbiol Res. 2016;3:190–3.CrossRefGoogle Scholar
- 126.Kaur R, Panda PS, Sardana K, Khan S. Mycological pattern of dermatomycoses in a tertiary care hospital. J Trop Med. 2015;2015:1–5.CrossRefGoogle Scholar
- 127.Poluri LV, Indugula JP, Kondapaneni SL. Clinicomycological study of dermatophytosis in South India. J Lab Physicians. 2015;7:84–9.PubMedPubMedCentralCrossRefGoogle Scholar
- 128.Agarwal US, Saran J, Agarwal P. Clinico-mycological study of dermatophytes in a tertiary care centre in Northwest India. Indian J Dermatol Venereol Leprol. 2014;80:194–5.PubMedCrossRefPubMedCentralGoogle Scholar
- 129.Bhagra S, Ganju SA, Kanga A, Sharma NL, Guleria RC. Mycological pattern of dermatophytosis in and around shimla hills. Indian J Dermatol. 2014;59:268–70.PubMedPubMedCentralCrossRefGoogle Scholar
- 130.Surendran K, Bhat RM, Boloor R, Nandakishore B, Sukumar D. A clinical and mycological study of dermatophytic infections. Indian J Dermatol. 2014;59:262–7.PubMedPubMedCentralCrossRefGoogle Scholar
- 131.Yadav P, Singal A, Pandhi D, Das S. Clinicomycological study of dermatophyte toenail onychomycosis in New Delhi, India. Indian J Dermatol. 2015;60:153–8.PubMedPubMedCentralCrossRefGoogle Scholar
- 132.Kumari B, Randi K, Sharma R. The major etiological cause in human dermatophytoses in Chennai. Int J Mycol Plant Pathog. 2014;1:42–4.Google Scholar
- 133.Lone R, Bashir D, Ahmad S, Syed A, Khurshid S. A study on clinico-mycological profile, aetiological agents and diagnosis of onychomycosis at a government medical college hospital in kashmir. J Clin Diagn Res. 2013;7:1983–5.PubMedPubMedCentralGoogle Scholar
- 134.Pandey A, Pandey M. Isolation and characterization of dermatophytes with tinea infections at Gwalior (MP), India. Int J Pharm Sci Inven. 2013;2:5–8.Google Scholar
- 135.Niranjan HP, Padmaja PB. Study of onychomycosis at a tertiary care hospital in South India. J Evol Med Dent Sci. 2012;1:823–9.CrossRefGoogle Scholar
- 136.Sahai S, Mishra D. Change in spectrum of dermatophytes isolated from superficial mycoses cases: first report from Central India. Indian J Dermatol Venereol Leprol. 2011;77:335–6.PubMedCrossRefPubMedCentralGoogle Scholar
- 137.Patel P, Mulla S, Disha Patel GS. A Study of superficial mycosis in South Gujarat region. Natl J Community Med. 2010;1:85–8.CrossRefGoogle Scholar
- 138.Adhikari L, Das Gupta A, Pal R, Singh TSK, Das GA, Pal R, TSK S. Clinico-etiologic correlates of onychomycosis in Sikkim. Indian J Pathol Microbiol. 2009;52:194–7.PubMedCrossRefPubMedCentralGoogle Scholar
- 139.Wu SX, Guo NR, Li XF, Liao WQ, Chen M, Zhang QQ, Li CY, Li RY, Bulmer GS, Li DM, Xi LY, Lu S, Liu B, Zheng YC, Ran YP, Kuan YZ. Human pathogenic fungi in China-emerging trends from ongoing National Survey for 1986, 1996, and 2006. Mycopathologia. 2011;171:387–93.PubMedCrossRefPubMedCentralGoogle Scholar
- 140.Zhu M, Li L, Wang J, Zhang C, Kang K, Zhang Q. Tinea capitis in Southeastern China: A 16-year survey. Mycopathologia. 2010;169:235–9.PubMedCrossRefPubMedCentralGoogle Scholar
- 141.Abastabar M, Haghani I, Shokohi T, Hedayati MT, Aghili SR, Jedi A, Dadashi S, Shabanzadeh S, Hosseini T, Aslani N, Meis JF, Badali H. Low in vitro antifungal activity of tavaborole against yeasts and molds from onychomycosis. Antimicrob Agents Chemother. 2018;62:e01632–18.PubMedPubMedCentralGoogle Scholar
- 142.Farokhipor S, Ghiasian SA, Nazeri H, Kord M, Didehdar M. Characterizing the clinical isolates of dermatophytes in Hamadan city, Central west of Iran, using PCR-RLFP method. J Mycol Med. 2018;28:101–5.PubMedCrossRefPubMedCentralGoogle Scholar
- 143.Haghani I, Shams-Ghahfarokhi M, Dalimi Asl A, Shokohi T, Hedayati MT. Molecular identification and antifungal susceptibility of clinical fungal isolates from onychomycosis (uncommon and emerging species). Mycoses. 2019;62:128–43.PubMedCrossRefPubMedCentralGoogle Scholar
- 144.Babayani M, Salari S, Hashemi SJ, Ghasemi Nejad Almani P, Fattahi A. Onychomycosis due to dermatophytes species in Iran: Prevalence rates, causative agents, predisposing factors and diagnosis based on microscopic morphometric findings. J Mycol Med. 2018;28:45–50.PubMedCrossRefPubMedCentralGoogle Scholar
- 145.Khosravi AR, Shokri H, Vahedi G. Factors in etiology and predisposition of adult tinea capitis and review of published literature. Mycopathologia. 2016;181:371–8.PubMedCrossRefPubMedCentralGoogle Scholar
- 146.Chadeganipour M, Mohammadi R, Shadzi S. A 10-year study of dermatophytoses in Isfahan, Iran. J Clin Lab Anal. 2016;30:103–7.PubMedCrossRefPubMedCentralGoogle Scholar
- 147.Rashidian S, Falahati M, Kordbacheh P, Mahmoudi M, Safara M, Sadeghi Tafti H, Mahmoudi S, Zaini F. A study on etiologic agents and clinical manifestations of dermatophytosis in Yazd, Iran. Curr Med Mycol. 2015;1:20–5.PubMedPubMedCentralCrossRefGoogle Scholar
- 148.Naseri A, Fata A, Najafzadeh MJ, Shokri H. Surveillance of dermatophytosis in Northeast of Iran (Mashhad) and review of published studies. Mycopathologia. 2013;176:247–53.PubMedCrossRefPubMedCentralGoogle Scholar
- 149.Bassiri-Jahromi S. Epidemiological trends in zoophilic and geophilic fungi in Iran. Clin Exp Dermatol. 2013;38:13–9.PubMedCrossRefPubMedCentralGoogle Scholar
- 150.Ansar A, Farshchian M, Nazeri H, Ghiasian SA. Clinico-epidemiological and mycological aspects of tinea incognito in Iran: A 16-year study. Japanese J Med Mycol. 2011;52:25–32.CrossRefGoogle Scholar
- 151.Pang SM, Pang JYY, Fook-Chong S, Tan AL. Tinea unguium onychomycosis caused by dermatophytes: a ten-year (2005-2014) retrospective study in a tertiary hospital in Singapore. Singap Med J. 2018;59:524–7.CrossRefGoogle Scholar
- 152.Do NA, Nguyen TD, Nguyen KL, Le TA. Distribution of species of dermatophyte among patients at a dermatology Centre of Nghean Province, Vietnam, 2015–2016. Mycopathologia. 2017;182:1061–7.PubMedCrossRefPubMedCentralGoogle Scholar
- 153.Ramalingam R, Kunalan S, Tang MM. Mycology of onychomycosis: A 5-year retrospective review (2011 – 2015) in hospital Kuala Lumpur. Med J Malaysia. 2017;72:190–2.PubMedPubMedCentralGoogle Scholar
- 154.Nussipov Y, Markabayeva A, Gianfaldoni S, Tchernev G, Wollina U, Lotti J, Roccia MG, Fioranelli M, Lotti T. Clinical and epidemiological features of dermatophyte infections in Almaty, Kazakhstan. Open Access Maced J Med Sci. 2017;5:409.PubMedPubMedCentralCrossRefGoogle Scholar
- 155.Khaled JM, Golah HA, Khalel AS, Alharbi NS, Mothana RA. Dermatophyte and non dermatophyte fungi in Riyadh City, Saudi Arabia. Saudi J Biol Sci. 2015;22:604–9.PubMedPubMedCentralCrossRefGoogle Scholar
- 156.Elmegeed A, Al Shimaa M, Ouf S, Moussa A, Tarek AA, Eltahlawi SMR. Dermatophytes and other associated fungi in patients attending to some hospitals in Egypt. Braz J Microbiol. 1973;46:799–805.CrossRefGoogle Scholar
- 157.Abu Shaqra QM, Al Momani W. Cases of tinea capitis as encountered in a private practice laboratory from Jordan. J Mycol Med. 2011;21:24–7.PubMedCrossRefPubMedCentralGoogle Scholar
- 158.Akcaglar S, Ener B, Toker SC, Ediz B, Tunali S, Tore O. A comparative study of dermatophyte infections in Bursa, Turkey. Med Mycol. 2011;49:602–7.PubMedPubMedCentralGoogle Scholar
- 159.Koksal F, Er E, Samasti M. Causative agents of superficial mycoses in Istanbul, Turkey: retrospective study. Mycopathologia. 2009;168:117–23.PubMedCrossRefPubMedCentralGoogle Scholar
- 160.Narang T, Manhas A, Aggarwal P, Bala M, Kaur M, Gupte S. Study of the distribution of Malassezia species in patients with pityriasis versicolor and healthy individuals in Tertiary Care Hospital, Punjab. Indian J Med Microbiol. 2013;31:270.PubMedCrossRefPubMedCentralGoogle Scholar
- 161.Jena DK, Sengupta S, Dwari BC, Ram MK. Pityriasis versicolor in the pediatric age group. Indian J Dermatol Venereol Leprol. 2005;71:259–61.PubMedCrossRefPubMedCentralGoogle Scholar
- 162.Dutta S, Bajaj AK, Basu S, Dikshit A. Pityriasis versicolor: socioeconomic and clinico-mycologic study in India. Int J Dermatol. 2002;41:823–4.PubMedCrossRefPubMedCentralGoogle Scholar
- 163.Zhang H, Ran Y, Xie Z, Zhang R. Identification of malassezia species in patients with seborrheic dermatitis in China. Mycopathologia. 2013;175:83–9.PubMedCrossRefPubMedCentralGoogle Scholar
- 164.Mansouri P, Farshi S, Hashemi J, Khosravi AR, Saghazadeh M. Identification of Malassezia species isolated from patients with seborrheic dermatitis, atopic dermatitis, and normal subjects. J Mycol Med. 2010;20:279–82.CrossRefGoogle Scholar
- 165.Rasi A, Naderi R, Behzadi AH, Falahati M, Farehyar S, Honarbakhsh Y, Akasheh AP. Malassezia yeast species isolated from Iranian patients with pityriasis versicolor in a prospective study. Mycoses. 2010;53:350–5.PubMedPubMedCentralGoogle Scholar
- 166.Tarazooie B, Kordbacheh P, Zaini F, Zomorodian K, Saadat F, Zeraati H, Hallaji Z, Rezaie S. Study of the distribution of Malassezia species in patients with pityriasis versicolor and healthy individuals in Tehran, Iran. BMC Dermatol. 2004;4:5.PubMedPubMedCentralCrossRefGoogle Scholar
- 167.Lyakhovitsky A, Shemer A, Amichai B. Molecular analysis of Malassezia species isolated from Israeli patients with pityriasis versicolor. Int J Dermatol. 2013;52:231–3.PubMedCrossRefPubMedCentralGoogle Scholar
- 168.Rodoplu G, Saracli MA, Gümral R, Taner Yildiran S. Distribution of Malassezia species in patients with pityriasis versicolor in Turkey. J Mycol Med. 2014;24:117–23.PubMedCrossRefPubMedCentralGoogle Scholar
- 169.Karakaş M, Turaç-Biçer A, Ilkit M, Durdu M, Seydaǒlu G. Epidemiology of pityriasis versicolor in adana, Turkey. J Dermatol. 2009;36:377–82.PubMedCrossRefPubMedCentralGoogle Scholar
- 170.Kamalam A, Thambiah AS. A study of 3891 cases of mycoses in the tropics. Sabouraudia. 1976;14:129–48.PubMedCrossRefPubMedCentralGoogle Scholar
- 171.Kiken DA, Sekaran A, Antaya RJ, Davis A, Imaeda S, Silverberg NB. White piedra in children. J Am Acad Dermatol. 2006;55:956–61.PubMedCrossRefPubMedCentralGoogle Scholar