Exhaled Breath: Another Biomarker Source That Is Complementary to Urine
Biomarkers are measurable changes associated with disease. Exhaled breath provides many signs of bodily changes and has been proposed to be a good early biomarker source because it lacks homeostatic mechanisms and the information contained in the breath complements to other similar body fluids, such as urine and tears. Earlier biomarker detection can provide earlier diagnosis, which can bring about more choices and more time for treatment. The benefit of studying exhaled breath in animal models is that most interfering factors can be avoided and earlier changes in disease may be found.
KeywordsExhaled breath Animal model Biomarkers VOCs Device
- Gao Y. Taking a deep breath. MOJ Proteomics Bioinformatics. 2015a;2Google Scholar
- Gao Y. Roadmap to the urine biomarker era. MOJ Proteomics Bioinformatics. 2015b;2Google Scholar
- Kang S, Paul Thomas CL. How long may a breath sample be stored for at −80 degrees C? A study of the stability of volatile organic compounds trapped onto a mixed Tenax: carbograph trap adsorbent bed from exhaled breath. J Breath Res. 2016;10:026011. https://doi.org/10.1088/1752-7155/10/2/026011.CrossRefPubMedGoogle Scholar