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Protecting the Children of HIV-Infected Mothers

  • Xi JinEmail author
  • Ailing Wang
  • Fang Wang
  • Yaping Qiao
  • Jessica Nan
Chapter

Abstract

Prevention of mother-to-child transmission (PMTCT) of HIV infection has been recognized as a high-priority component of China’s national HIV/AIDS response since it launched its National HIV PMTCT Program in 2005. However, the growing realization of the high rate of mother-to-child transmission of other serious infectious diseases, particularly syphilis and hepatitis B virus (HBV), led the Chinese Central Government to design a more comprehensive program and to integrate that program into the existing maternal and child health (MCH) system. Thus, the National PMTCT Program for HIV, Syphilis, and HBV was launched in 2010. Three years later coverage had already increased to 40% and today is universal. As a result, HIV testing rates among pregnant women have increased from 58% in 2005 to over 99% in 2017, the proportion of HIV-infected pregnant women receiving treatment increased from 65% in 2005 to 90% in 2017, and the rate of HIV MTCT fell from 13% in 2005 to 5% in 2017. Similarly, improved outcomes were also observed for syphilis- and HBV-infected mothers and their infants.

Notes

Acknowledgments

The authors would like to thank Jennifer M. McGoogan for editorial assistance.

References

  1. Chen KT, Qian HZ. Mother to child transmission of HIV in China. BMJ. 2005;330(7503):1282–3.  https://doi.org/10.1136/bmj.330.7503.1282.CrossRefPubMedPubMedCentralGoogle Scholar
  2. Du Y, Wang Y. The development and prospect of China maternal and child health services. Chin J Prev Med. 2008;42:104–6.Google Scholar
  3. Gong X, Yue XL, Teng F, Jiang N, Men PX. Syphilis in China from 2000 to 2013: epidemical trends and characteristics. Chin J Dermatol. 2014;5(47):310–5.Google Scholar
  4. Gui X, Luo J, Zhuang K. The survey on intrafamilial transmission of HIV. Chin J Epidemiol. 2003;24(5):396.  https://doi.org/10.3760/j.issn:0254-6450.2003.05.030.CrossRefGoogle Scholar
  5. Li GH, Cheng HH, He Y, Sun F, Zhou ZQ, Duan S, et al. An investigation on HIV-1 transmission from mother to children in selected areas of China. Chin J STD AIDS Prev Cont. 2002;8(4):204–7.  https://doi.org/10.3969/j.issn.1672-5662.2002.04.004.CrossRefGoogle Scholar
  6. Liang X, Bi SL, Yang WZ, Wang LD, Cui G, Cui FQ, et al. Epidemiological serosurvey of hepatitis B in China—declining HBV prevalence due to hepatitis B vaccination. Vaccine. 2009;27(47):6550–7.CrossRefGoogle Scholar
  7. Luo Z, Li L, Ruan B. Impact of the implementation of a vaccination strategy on hepatitis B virus infections in China over a 20-year period. Int J Infect Dis. 2012;16(2):e82–8.  https://doi.org/10.1016/j.ijid.2011.10.009.CrossRefPubMedGoogle Scholar
  8. Ma Y, Dou Z, Guo W, Mao Y, Zhang F, McGoogan JM, et al. The human immunodeficiency virus care continuum in China: 1985–2015. Clin Infect Dis. 2018;66(6):833–9.  https://doi.org/10.1093/cid/cix911.CrossRefGoogle Scholar
  9. Ministry of Health. Implementation plan for prevention of mother-to-child transmission of HIV (trial). Beijing: Ministry of Health of the People’s Republic of China; 2004.Google Scholar
  10. National Bureau of Statistics of China. China statistical yearbook 2017. National Bureau of Statistics of China Beijing . http://www.stats.gov.cn/tjsj/ndsj/2017/indexeh.htm. Accessed 22 Aug 2018.
  11. Wang AL, Qiao YP, Wang LH, Fang LW, Wang F, Jin X, et al. Integrated prevention of mother-to-child transmission for human immunodeficiency virus, syphilis and hepatitis B virus in China. Bull World Health Organ. 2015;93(1):52–6.  https://doi.org/10.2471/BLT.14.139626.CrossRefPubMedGoogle Scholar
  12. Wang L, Fang L, Wang Q, Jiang Y, Gong SY, Zhang Q, et al. The rate and stages of HIV mother to child transmission in some areas of China with relatively high HIV/AIDS prevalence and evaluation of the effectiveness of relevant interventions. Chin J AIDS STD. 2008;14(5):435–8.  https://doi.org/10.3969/j.issn.1672-5662.2008.05.001.CrossRefGoogle Scholar
  13. Wu Z, Tang Z, Mao Y, Van Veldhuisen P, Ling W, Liu D, et al. Testing and linkage to HIV care in China: a cluster-randomised trial. Lancet HIV. 2017;4(12):e555–65.  https://doi.org/10.1016/S2352-3018(17)30131-5.CrossRefPubMedPubMedCentralGoogle Scholar
  14. Xia GL, Liu CB, Cao HL, Bi SL, Zhan MY, Su CA, et al. Prevalence of hepatitis B and C virus infections in the general Chinese population. Results from a nationwide cross-sectional seroepidemiologic study of hepatitis A, B, C, D and E virus infections in China, 1992. Int Hepatol Commun. 1996;5(1):62–73.  https://doi.org/10.1016/S0928-4346(96)82012-3.CrossRefGoogle Scholar
  15. Zhang XY, Huang T, Feng YB, Li M Chen FF, Li YG, et al. Characteristics of the HIV/AIDS epidemic among women aged 15–49 years from 2005 to 2012 in China. Biomed Environ Sci. 2015;28(10):701–8.  https://doi.org/10.3967/bes2015.100.CrossRefPubMedGoogle Scholar

Copyright information

© Springer Nature Singapore Pte Ltd. 2020

Authors and Affiliations

  • Xi Jin
    • 1
    Email author
  • Ailing Wang
    • 1
  • Fang Wang
    • 1
  • Yaping Qiao
    • 1
  • Jessica Nan
    • 2
  1. 1.National Center for Women and Children’s HealthChina CDCBeijingChina
  2. 2.US CDC GAP, China OfficeBeijingChina

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