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Taurine 11 pp 197-203 | Cite as

Taurine Promotes In-vitro Follicle Development, Oocyte Maturation, Fertilization and Cleavage of rats

  • Teng Mu
  • Ying Feng
  • Yuchen Che
  • Qiufeng Lv
  • Jianmin Hu
  • Qunhui Yang
  • Jiancheng Yang
Conference paper
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 1155)

Abstract

It is well known that a large quantity of taurine is present in mammalian ovaries. Taurine reportedly promotes the secretion of female reproductive hormones by stimulating hypothalamus-pituitary-gonadal axis function. Therefore, we speculated that taurine may have beneficial effects on follicle growth, oocyte maturation, fertilization and cleavage. Here, we cultured rat follicles, immature oocytes and sperms in vitro and treated with taurine to observe the changes in follicle diameter, estradiol concentration as well as the rate of oocytes maturation, fertilization and cleavage using an inverted microscope. The results showed that taurine can elevate ovarian follicles growth and oocyte maturation, fertilization, and cleavage rates in vitro, which may be attributed to its osmoregulation and stimulation on the estradiol secretion. Our results provide important insights into taurine application in female production, although the underlying mechanism need to be further addressed.

Keywords

Taurine Follicle development Oocytes maturation Fertilization Cleavage Rat 

Notes

Acknowledgements

This work was supported by the National Natural Science Foundation of China (31302051) and Cultivation Plan for Youth Agricultural Science and Technology Innovative Talents of Liaoning Province (No. 2014049).

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Copyright information

© Springer Nature Singapore Pte Ltd. 2019

Authors and Affiliations

  • Teng Mu
    • 1
    • 2
  • Ying Feng
    • 3
  • Yuchen Che
    • 4
  • Qiufeng Lv
    • 3
  • Jianmin Hu
    • 3
  • Qunhui Yang
    • 3
  • Jiancheng Yang
    • 3
  1. 1.Liaoning Provincial Key Laboratory of Zoonoses, College of Animal Science & Veterinary MedicineShenyang Agricultural UniversityShenyangPeople’s Republic of China
  2. 2.Academy of Life SciencesLiaoning UniversityShenyangPeople’s Republic of China
  3. 3.Liaoning Provincial Key Laboratory of Zoonosis, College of Animal Science & Veterinary MedicineShenyang Agricultural UniversityShenyangPeople’s Republic of China
  4. 4.School of Basic Medical ScienceShenyang Medical CollegeShenyangPeople’s Republic of China

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