Uveitis and Autoimmune Diseases

  • Meifen Zhang
  • Bo Wan
Part of the Advances in Visual Science and Eye Diseases book series (AVSED, volume 3)


The uvea is the predilection site of ocular immune diseases, due to its features like peripheral immune organ, with abundant vessels and some other ocular antigenic substances such as lens and retinal antigens, which could easily induce the immune-related ocular diseases. Uveitis has many complex symptoms, signs, and causes. Additionally, limitations of understanding of immune diseases could lead to the difficulty of diagnosing. This part introduces the involvement and manifestations of autoimmune diseases on uvea, and correlation between the immune-related manifestations of uveitis and systemic immune diseases. “Get the big picture from small details” to reveal the relationship between eye diseases and immune diseases, as from the perspective of integrative medicine, it would be examined and identified for that whether the uveitis is caused by immune diseases, whether the systemic immune disease affects the eye, what is the relevant diagnostic criteria for immune-related eye diseases, what are the examinations to do, and how to treat. By the establishment of integrative medical thought, broadening minds, understanding the performance of systemic immune diseases, asking history, and checking physical signs, early diagnosis and early treatment could be made, and thus the possibility of misdiagnosis and missed diagnosis of immune-associated uveitis would be decreased.


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Copyright information

© Springer Nature Singapore Pte Ltd. and People's Medical Publishing House, PR of China 2020

Authors and Affiliations

  • Meifen Zhang
    • 1
  • Bo Wan
    • 1
  1. 1.Department of OphthalmologyPeking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina

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