Laboratory Monitoring of Anticoagulant therapy
Worldwide, millions of patients are put on short-term and long-term anticoagulant therapy for several thrombotic indications. The critical balance of the inherent risk of bleeding and the anticoagulant effect of these drugs needs to be maintained. There is an increasing use of new oral anticoagulants apart from the conventional agents such as heparin and vitamin K antagonists, and it is imperative to know the appropriate assay(s) that are used for each drug monitoring. Hence, both clinical and laboratory personnel should be aware of assays to monitor different anticoagulant therapy and various physiological as well as laboratory variables affecting these results.
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